Whatever works: Uncertainty and technological hybrids in medical innovation

The persistent uncertainty that looms over the search for solutions to health problems offers important conceptual insights for the study of technological change. This paper explores the notion of hybridization, namely the embodiment of multiple competing operational principles within a single medical device, as strategy to deal with the practical shortcomings due to said uncertainty. The history of the development of the hybrid artificial disc affords the elaboration of an alternative view of hybridization and, at the same time, the articulation of a dualism between medical science as area of basic research (e.g. what disease is) and as practical knowledge (e.g. how disease can be tackled).Barberá Tomás, JD.; Consoli, D. (2012). Whatever works: Uncertainty and technological hybrids in medical innovation. Technological Forecasting and Social Change. 79(5):932-948. doi:10.1016/j.techfore.2011.12.009S93294879

Predicting Corrosion Damage in the Human Body Using Artificial Intelligence: In Vitro Progress and Future Applications Applications

Artificial intelligence (AI) is used in the clinic to improve patient care. While the successes illustrate the impact AI can have, few studies have led to improved clinical outcomes. A gap in translational studies, beginning at the basic science level, exists. In this review, we focus on how AI models implemented in non-orthopedic fields of corrosion science may apply to the study of orthopedic alloys. We first define and introduce fundamental AI concepts and models, as well as physiologically relevant corrosion damage modes. We then systematically review the corrosion/AI literature. Finally, we identify several AI models that may be Preprint implemented to study fretting, crevice, and pitting corrosion of titanium and cobalt chrome alloys

A Case Study on the Efficacy of STEM Pedagogy in Central New York State: Examining STEM Engagement Gaps Affecting Outcomes for High School Seniors and Post-2007 Educational Leadership Interventions to Reinforce STEM Persistence with Implications of STEM Theoretic Frameworks on Artificial Intelligence / Machine Learning

STEM (science, technology, engineering, and mathematics) has gained significant notoriety and momentum in recent years. STEM literacy highlights the vital connection between an educated STEM workforce and U.S. national prosperity and leadership. STEM educational and job placement goals have been a national priority for over the past 20 years. However, the STEM gap is widening—contributing to increasing STEM pipeline leakage and the social injustice milieu of a noncompetitive workforce— undermining efforts to create prosperity and sustain global leadership. The pace of STEM jobs filled lags the rate of technological advancement and the surges in skilled STEM labor demand. The aggregate disparity over time has troubling implications. The purpose of the study was to examine the STEM gap touchpoints for a Central New York high school during the transition period upon entering college or the workforce. A qualitative case study used Lesh’s translation model as a research framework. A semi-structured, focus group protocol was employed to gain a fresh perspective on the STEM gap problem and identify purposeful interventions. A major finding was the slow pace of adopting institutional reforms that replaces standardscompetency-based learning with progressive application- and outcome-based pedagogy. The study has implications for school districts, secondary schools, and higher education teacher preparedness programs in STEM pedagogy and curriculum development. A knowledge-based, progressive STEM theoretic framework with pedagogical scaffolding is conceptualized rooted in artificial intelligence and machine learning. The study presents recommendations for school districts, secondary education teachers, state education and legislative leaders, higher education institutions, and future research

Ti-6Al-4V β Phase Selective Dissolution: In Vitro Mechanism and Prediction

Retrieval studies document Ti-6Al-4V β phase dissolution within total hip replacement systems. A gap persists in our mechanistic understanding and existing standards fail to reproduce this damage. This thesis aims to (1) elucidate the Ti-6Al-4V selective dissolution mechanism as functions of solution chemistry, electrode potential and temperature; (2) investigate the effects of adverse electrochemical conditions on additively manufactured (AM) titanium alloys and (3) apply machine learning to predict the Ti-6Al-4V dissolution state. We hypothesized that (1) cathodic activation and inflammatory species (H2O2) would degrade the Ti-6Al-4V oxide, promoting dissolution; (2) AM Ti-6Al-4V selective dissolution would occur and (3) near field electrochemical impedance spectra (nEIS) would distinguish between dissolved and polished Ti-6Al-4V, allowing for deep neural network prediction. First, we show a combinatorial effect of cathodic activation and inflammatory species, degrading the oxide film’s polarization resistance (Rp) by a factor of 105 Ωcm2 (p = 0.000) and inducing selective dissolution. Next, we establish a potential range (-0.3 V to –1 V) where inflammatory species, cathodic activation and increasing solution temperatures (24 oC to 55 oC) synergistically affect the oxide film. Then, we evaluate the effect of solution temperature on the dissolution rate, documenting a logarithmic dependence. In our second aim, we show decreased AM Ti-6Al-4V Rp when compared with AM Ti-29Nb-21Zr in H2O2. AM Ti-6Al-4V oxide degradation preceded pit nucleation in the β phase. Finally, in our third aim, we identified gaps in the application of artificial intelligence to metallic biomaterial corrosion. With an input of nEIS spectra, a deep neural network predicted the surface dissolution state with 96% accuracy. In total, these results support the inclusion of inflammatory species and cathodic activation in pre-clinical titanium devices and biomaterial testing

DETECTION AND HANDLING EXCEPTIONS IN BUSINESS PROCESS MANAGEMENT SYSTEMS USING ACTIVE SEMANTIC MODEL

Although business process management systems (BPM) have been used over the years, their performance in unpredicted situations has not been adequately solved. In these cases, it is common to request user assistance or invoke predefined procedures. In this paper, we propose using the Active Semantic Model (ASM) to detect and handle exceptions. This is a specifically developed semantic network model for modeling of semantic features of the business processes. ASM is capable of classifying new situations based on their similarities with existing ones. Within BPM systems this is then used to classify new situations as exceptions and to handle the exceptions by changing the process based on ASM’s previous experience. This enables automatic detection and handling of exceptions which significantly improves the performance of bpm systems

Exploring the use of Artificial Intelligent Systems in STEM Classrooms

Human beings by nature have a predisposition towards learning and the exploration of the natural world. We are intrinsically intellectual and social beings knitted with adaptive cognitive architectures. As Foot (2014) succinctly sums it up: “humans act collectively, learn by doing, and communicate in and via their actions” and they “… make, employ, and adapt tools of all kinds to learn and communicate” and “community is central to the process of making and interpreting meaning—and thus to all forms of learning, communicating, and acting” (p.3). Education remains pivotal in the transmission of social values including language, knowledge, science, technology, and an avalanche of others. Indeed, Science, Technology, Engineering, and Mathematics (STEM) have been significant to the advancement of social cultures transcending every epoch to contemporary times. As Jasanoff (2004) poignantly observed, “the ways in which we know and represent the world (both nature and society) are inseparable from the ways in which we choose to live in it. […] Scientific knowledge [..] both embeds and is embedded in social practices, identities, norms, conventions, discourses, instruments, and institutions” (p.2-3). In essence, science remains both a tacit and an explicit cultural activity through which human beings explore their own world, discover nature, create knowledge and technology towards their progress and existence. This has been possible through the interaction and applications of artifacts, tools, and technologies within the purviews of their environments. The applications of technologies are found across almost every luster of organizational learning especially teacher education, STEM, architecture, manufacturing, and a flurry of others. Thus, human evolution and development are inexplicably linked with education either formally or informally. The 21st century has however seen a surge in the use of artificial intelligence (AI) and digital technologies in education. The proliferation of artificial intelligence and associated technologies are creating new overtures of digital multiculturalism with distinct worldviews of significance to education. For example, learners are demonstrating digital literacy skills and are knowledgeable about AI technologies across every specter of their lives (Bennett et al., 2008). It is also opening new artesian well-springs of educational opportunities and pedagogical applications. This includes mapping new methodological pathways, content creation and curriculum design, career preparations and indeed a seemingly new paradigm shift in teaching STEM. There is growing scholarly evidence about the use and diffusion of these technologies in K-12 and higher education (Bonk & Graham, 2012; Hew & Brush, 2007; Langer, 2018; Mishra & Koehler, 2006). Some of these include the Sphero robots, Micro Bit, Jill Watson, BrickPi3 Classroom kit, Engino STEM Mechanic, Lego Education WeDo Core Set and Spike. Both educators and learners are using these in STEM programs as well as other education related activities. Just as human activities and interactions with artifacts and tools shaped and redefined the scientific-technological feat of previous generations, so the contemporary digital technological era seems to be on a similar trajectory. However, there is sparsity of empirical scholarship on the pedagogical prospects and effectiveness of artificial intelligence in STEM classrooms. Also, it should be noted that scholarship on how AI impacts pedagogical content knowledge of STEM educators and how learners perceive these technologies are just emerging. In addition, the recent COVID-19 pandemic (Ghandhi et al., 2020; Rasmussen et al., 2020) has unexpectedly created a renewed synergy towards the applications of digital technologies in teaching STEM. In the context of this force majeure (COVID-19), the traditional brick and mortar educational spaces metamorphosed into digital spaces with the applications of many artificial intelligent technologies and resources in the arena of education. This doctoral dissertation study examined these enigmas including how educators use these technologies in STEM classrooms. The study is informed by activity theory or cultural-historical activity theory (Engeström et al., 2007; Hasan et al., 2014; Krinski & Barker, 2009; Oers, 2010; Vygotsky,1987). The study participants will be selected from educators currently integrating artificial intelligent systems and digital technologies in their respective STEM classrooms. Pre-data survey inquiry has shown that many educators were incorporating some forms of AIS into their STEM classrooms. In view of these, I have explored Sphero educational robots to interrogate the research topic. The Sphero Edu described as a “…STEAM-based toolset that weaves hardware, software, and community engagement to promote 21st century skills. While these skills are absolutely crucial, our edu program goes beyond code by nurturing students’ creativity and ingenuity like no other education program can” (Sphero, April 2020). The Sphero robots also have features and applications for designing and teaching STEM topics such as nature, space science, geometry, and other activities of pedagogical significance. Users could also design and write advanced engineering programs in JavaScript during STEM educational activities formally and outside of the classrooms. In essence, educators and students can learn designing, programming, engineering, mathematics, computational thinking, and hands-on skills reflective of the 21st century. In brief, the dissertation study research has explored artificial intelligence and emerging technologies and how these could transform and advance teaching and learning of STEM hence the research topic: Exploring the use of Artificial Intelligent Systems in STEM Classrooms. Methodologically, this is a qualitative study through the theoretical frameworks of activity theory as applicable to STEM education. The main research questions are: 1) Given that artificial intelligent systems and digital technologies have been applied in STEM educational domains (content, pedagogy, student learning, assessment). How does the application of AIS and digital technologies impact pedagogy in STEM educational activities? 2) Given that digital technology is transforming contemporary society in every facet. How/What does AIS tell us about how digital technology impacts STEM pedagogy? Data was collected from the study participants, archival sources, and others for analyses. It is hoped that the findings will inform and address theories of learning and teaching, policy and praxis in science education, teacher preparatory and professional development programs as it relates to STEM classroom

Life Expansion: Toward an Artistic, Design-Based Theory of the Transhuman / Posthuman

The thesis’ study of life expansion proposes a framework for artistic, design-based approaches concerned with prolonging human life and sustaining personal identity. To delineate the topic: life expansion means increasing the length of time a person is alive and diversifying the matter in which a person exists. For human life, the length of time is bounded by a single century and its matter is tied to biology. Life expansion is located in the domain of human enhancement, distinctly linked to technological interfaces with biology. The thesis identifies human-computer interaction and the potential of emerging and speculative technologies as seeding the promulgation of human enhancement that approach life expansion. In doing so, the thesis constructs an inquiry into historical and current attempts to append human physiology and intervene with its mortality. By encountering emerging and speculative technologies for prolonging life and sustaining personal identity as possible media for artistic, design-based approaches to human enhancement, a new axis is sought that identifies the transhuman and posthuman as conceptual paradigms for life expansion. The thesis asks: What are the required conditions that enable artistic, design-based approaches to human enhancement that explicitly pursue extending human life? This question centers on the potential of the study’s proposed enhancement technologies in their relationship to life, death, and the human condition. Notably, the thesis investigates artistic approaches, as distinct from those of the natural sciences, and the borders that need to be mediated between them. The study navigates between the domains of life extension, art and design, technology, and philosophy in forming the framework for a theory of life expansion. The critical approach seeks to uncover invisible borders between these interconnecting forces by bringing to light issues of sustaining life and personal identity, ethical concerns, including morphological freedom and extinction risk. Such issues relate to the thesis’ interest in life expansion and the use emerging and speculative technologies. 4 The study takes on a triad approach in its investigation: qualitative interviews with experts of the emerging and speculative technologies; field studies encountering research centers of such technologies; and an artistic, autopoietic process that explores the heuristics of life expansion. This investigation forms an integrative view of the human use of technology and its melioristic aim. The outcome of the research is a theoretical framework for further research in artistic approaches to life expansion

Design and testing of additively manufactured lattice structures for musculoskeletal applications

Additive manufacturing (AM) methods present a new frontier in engineering, allowing the fabrication of porous lattice structures with tailored mechanical properties. AM structures can be made using bio-inert metals, creating controlled stiffness biomaterials. As bone formation is strain dependent, these AM biomaterials can be used in implants to optimise the strain in surrounding trabecular bone for peak bone formation. However, the behaviour of AM lattices varies and is subject to manufacturing constraints. The aim of this PhD was to investigate the mechanical behaviour of AM lattices, and maximise the clinical benefits of AM for musculoskeletal applications. Lattice architecture was shown to affect the anisotropy of an AM lattice biomaterial, increasing the stiffness in directions not often tested in the literature. The mechanical and morphological properties of individual struts within powder bed fusion (PBF) lattices were also shown to vary depending on the orientation of the struts to the build direction. The ultimate tensile strength of titanium alloy (Ti6Al4V) struts more than doubled when built at a low angle versus perpendicular to the build platform, and other properties were substantially lower than for the bulk material. Geometric imperfections were found for struts built at low angles. As such, a low stiffness modified stochastic lattice was designed and tested which avoided the problems found with struts built at low angles. The resulting lattice had improved stiffness isotropy and could be used for musculoskeletal applications, tuned to match the mechanical properties in local trabecular bone and enhancing bone formation.Open Acces

Analysis and enhancement of interpersonal coordination using inertial measurement unit solutions

Die heutigen mobilen Kommunikationstechnologien haben den Umfang der verbalen und textbasierten Kommunikation mit anderen Menschen, sozialen Robotern und künstlicher Intelligenz erhöht. Auf der anderen Seite reduzieren diese Technologien die nonverbale und die direkte persönliche Kommunikation, was zu einer gesellschaftlichen Thematik geworden ist, weil die Verringerung der direkten persönlichen Interaktionen eine angemessene Wahrnehmung sozialer und umgebungsbedingter Reizmuster erschweren und die Entwicklung allgemeiner sozialer Fähigkeiten bremsen könnte. Wissenschaftler haben aktuell die Bedeutung nonverbaler zwischenmenschlicher Aktivitäten als soziale Fähigkeiten untersucht, indem sie menschliche Verhaltensmuster in Zusammenhang mit den jeweilgen neurophysiologischen Aktivierungsmustern analzsiert haben. Solche Querschnittsansätze werden auch im Forschungsprojekt der Europäischen Union "Socializing sensori-motor contingencies" (socSMCs) verfolgt, das darauf abzielt, die Leistungsfähigkeit sozialer Roboter zu verbessern und Autismus-Spektrumsstörungen (ASD) adäquat zu behandeln. In diesem Zusammenhang ist die Modellierung und das Benchmarking des Sozialverhaltens gesunder Menschen eine Grundlage für theorieorientierte und experimentelle Studien zum weiterführenden Verständnis und zur Unterstützung interpersoneller Koordination. In diesem Zusammenhang wurden zwei verschiedene empirische Kategorien in Abhängigkeit von der Entfernung der Interagierenden zueinander vorgeschlagen: distale vs. proximale Interaktionssettings, da sich die Struktur der beteiligten kognitiven Systeme zwischen den Kategorien ändert und sich die Ebene der erwachsenden socSMCs verschiebt. Da diese Dissertation im Rahmen des socSMCs-Projekts entstanden ist, wurden Interaktionssettings für beide Kategorien (distal und proximal) entwickelt. Zudem wurden Ein-Sensor-Lösungen zur Reduzierung des Messaufwands (und auch der Kosten) entwickelt, um eine Messung ausgesuchter Verhaltensparameter bei einer Vielzahl von Menschen und sozialen Interaktionen zu ermöglichen. Zunächst wurden Algorithmen für eine kopfgetragene Trägheitsmesseinheit (H-IMU) zur Messung der menschlichen Kinematik als eine Ein-Sensor-Lösung entwickelt. Die Ergebnisse bestätigten, dass die H-IMU die eigenen Gangparameter unabhängig voneinander allein auf Basis der Kopfkinematik messen kann. Zweitens wurden—als ein distales socSMC-Setting—die interpersonellen Kopplungen mit einem Bezug auf drei interagierende Merkmale von „Übereinstimmung“ (engl.: rapport) behandelt: Positivität, gegenseitige Aufmerksamkeit und Koordination. Die H-IMUs überwachten bestimmte soziale Verhaltensereignisse, die sich auf die Kinematik der Kopforientierung und Oszillation während des Gehens und Sprechens stützen, so dass der Grad der Übereinstimmung geschätzt werden konnte. Schließlich belegten die Ergebnisse einer experimentellen Studie, die zu einer kollaborativen Aufgabe mit der entwickelten IMU-basierten Tablet-Anwendung durchgeführt wurde, unterschiedliche Wirkungen verschiedener audio-motorischer Feedbackformen für eine Unterstützung der interpersonellen Koordination in der Kategorie proximaler sensomotorischer Kontingenzen. Diese Dissertation hat einen intensiven interdisziplinären Charakter: Technologische Anforderungen in den Bereichen der Sensortechnologie und der Softwareentwicklung mussten in direktem Bezug auf vordefinierte verhaltenswissenschaftliche Fragestellungen entwickelt und angewendet bzw. gelöst werden—und dies in zwei unterschiedlichen Domänen (distal, proximal). Der gegebene Bezugsrahmen wurde als eine große Herausforderung bei der Entwicklung der beschriebenen Methoden und Settings wahrgenommen. Die vorgeschlagenen IMU-basierten Lösungen könnten dank der weit verbreiteten IMU-basierten mobilen Geräte zukünftig in verschiedene Anwendungen perspektiv reich integriert werden.Today’s mobile communication technologies have increased verbal and text-based communication with other humans, social robots and intelligent virtual assistants. On the other hand, the technologies reduce face-to-face communication. This social issue is critical because decreasing direct interactions may cause difficulty in reading social and environmental cues, thereby impeding the development of overall social skills. Recently, scientists have studied the importance of nonverbal interpersonal activities to social skills, by measuring human behavioral and neurophysiological patterns. These interdisciplinary approaches are in line with the European Union research project, “Socializing sensorimotor contingencies” (socSMCs), which aims to improve the capability of social robots and properly deal with autism spectrum disorder (ASD). Therefore, modelling and benchmarking healthy humans’ social behavior are fundamental to establish a foundation for research on emergence and enhancement of interpersonal coordination. In this research project, two different experimental settings were categorized depending on interactants’ distance: distal and proximal settings, where the structure of engaged cognitive systems changes, and the level of socSMCs differs. As a part of the project, this dissertation work referred to this spatial framework. Additionally, single-sensor solutions were developed to reduce costs and efforts in measuring human behaviors, recognizing the social behaviors, and enhancing interpersonal coordination. First of all, algorithms using a head worn inertial measurement unit (H-IMU) were developed to measure human kinematics, as a baseline for social behaviors. The results confirmed that the H-IMU can measure individual gait parameters by analyzing only head kinematics. Secondly, as a distal sensorimotor contingency, interpersonal relationship was considered with respect to a dynamic structure of three interacting components: positivity, mutual attentiveness, and coordination. The H-IMUs monitored the social behavioral events relying on kinematics of the head orientation and oscillation during walk and talk, which can contribute to estimate the level of rapport. Finally, in a new collaborative task with the proposed IMU-based tablet application, results verified effects of different auditory-motor feedbacks on the enhancement of interpersonal coordination in a proximal setting. This dissertation has an intensive interdisciplinary character: Technological development, in the areas of sensor and software engineering, was required to apply to or solve issues in direct relation to predefined behavioral scientific questions in two different settings (distal and proximal). The given frame served as a reference in the development of the methods and settings in this dissertation. The proposed IMU-based solutions are also promising for various future applications due to widespread wearable devices with IMUs.European Commission/HORIZON2020-FETPROACT-2014/641321/E