7,914 research outputs found

    An adaptive stereo basis method for convolutive blind audio source separation

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    NOTICE: this is the author’s version of a work that was accepted for publication in Neurocomputing. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in PUBLICATION, [71, 10-12, June 2008] DOI:neucom.2007.08.02

    Dynamic Decomposition of Spatiotemporal Neural Signals

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    Neural signals are characterized by rich temporal and spatiotemporal dynamics that reflect the organization of cortical networks. Theoretical research has shown how neural networks can operate at different dynamic ranges that correspond to specific types of information processing. Here we present a data analysis framework that uses a linearized model of these dynamic states in order to decompose the measured neural signal into a series of components that capture both rhythmic and non-rhythmic neural activity. The method is based on stochastic differential equations and Gaussian process regression. Through computer simulations and analysis of magnetoencephalographic data, we demonstrate the efficacy of the method in identifying meaningful modulations of oscillatory signals corrupted by structured temporal and spatiotemporal noise. These results suggest that the method is particularly suitable for the analysis and interpretation of complex temporal and spatiotemporal neural signals

    Block-Online Multi-Channel Speech Enhancement Using DNN-Supported Relative Transfer Function Estimates

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    This work addresses the problem of block-online processing for multi-channel speech enhancement. Such processing is vital in scenarios with moving speakers and/or when very short utterances are processed, e.g., in voice assistant scenarios. We consider several variants of a system that performs beamforming supported by DNN-based voice activity detection (VAD) followed by post-filtering. The speaker is targeted through estimating relative transfer functions between microphones. Each block of the input signals is processed independently in order to make the method applicable in highly dynamic environments. Owing to the short length of the processed block, the statistics required by the beamformer are estimated less precisely. The influence of this inaccuracy is studied and compared to the processing regime when recordings are treated as one block (batch processing). The experimental evaluation of the proposed method is performed on large datasets of CHiME-4 and on another dataset featuring moving target speaker. The experiments are evaluated in terms of objective and perceptual criteria (such as signal-to-interference ratio (SIR) or perceptual evaluation of speech quality (PESQ), respectively). Moreover, word error rate (WER) achieved by a baseline automatic speech recognition system is evaluated, for which the enhancement method serves as a front-end solution. The results indicate that the proposed method is robust with respect to short length of the processed block. Significant improvements in terms of the criteria and WER are observed even for the block length of 250 ms.Comment: 10 pages, 8 figures, 4 tables. Modified version of the article accepted for publication in IET Signal Processing journal. Original results unchanged, additional experiments presented, refined discussion and conclusion

    Resistojet systems studies directed to the space station/space base. Volume 2 - Biowaste resistojet system development program Final report

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    Space station/base biowaste resistojet system for orbit keeping and control moment gyro desaturation - systems developmen

    ERPs and their brain sources in perceptual and conceptual prospective memory tasks: commonalities and differences between the two tasks

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    The present study examined whether Event-Related Potential (ERP) components and their neural generators are common to perceptual and conceptual prospective memory (PM) tasks or specific to the form of PM cue involved. We used Independent Component Analysis (ICA) to study the contributions of brain source activities to scalp ERPs across the different phases of two event-based PM-tasks: (1) holding intentions during a delay (monitoring) (2) detecting the correct context to perform the delayed intention (cue detection) and (3) carrying out the action (realisation of delayed intentions). Results showed that monitoring for both perceptual and conceptual PM-tasks was characterised by an enhanced early occipital negativity (N200). In addition the conceptual PM-task showed a long-lasting effect of monitoring significant around 700 ms. Perceptual PM-task cues elicited an N300 enhancement associated with cue detection, whereas a midline N400-like response was evoked by conceptual PM-task cues. The Prospective Positivity associated with realisation of delayed intentions was observed in both conceptual and perceptual tasks. A common frontal-midline brain source contributed to the Prospective Positivity in both tasks and a strong contribution from parieto-frontal brain sources was observed only for the perceptually cued PM-task. These findings support the idea that: (1) The enhanced N200 can be understood as a neural correlate of a ‘retrieval mode’ for perceptual and conceptual PM-tasks, and additional strategic monitoring is implemented according the nature of the PM task; (2) ERPs associated with cue detection are specific to the nature of the PM cues; (3) Prospective Positivity reflects a general PM process, but the specific brain sources contributing to it depend upon the nature of the PM task

    Characterization of Dynamic Structures Using Parametric and Non-parametric System Identification Methods

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    The effects of soil-foundation-structure (SFS) interaction and extreme loading on structural behaviors are important issues in structural dynamics. System identification is an important technique to characterize linear and nonlinear dynamic structures. The identification methods are usually classified into the parametric and non-parametric approaches based on how to model dynamic systems. The objective of this study is to characterize the dynamic behaviors of two realistic civil engineering structures in SFS configuration and subjected to impact loading by comparing different parametric and non-parametric identification results. First, SFS building models were studied to investigate the effects of the foundation types on the structural behaviors under seismic excitation. Three foundation types were tested including the fixed, pile and box foundations on a hydraulic shake table, and the dynamic responses of the SFS systems were measured with the instrumented sensing devices. Parametric modal analysis methods, including NExT-ERA, DSSI, and SSI, were studied as linear identification methods whose governing equations were modeled based on linear equations of motion. NExT-ERA, DSSI, and SSI were used to analyze earthquake-induced damage effects on the global behavior of the superstructures for different foundation types. MRFM was also studied to characterize the nonlinear behavior of the superstructure during the seismic events. MRFM is a nonlinear non-parametric identification method which has advantages to characterized local nonlinear behaviors using the interstory stiffness and damping phase diagrams. The major findings from the SFS study are: *The investigated modal analysis methods identified the linearized version of the model behavior. The change of global structural behavior induced by the seismic damage could be quantified through the modal parameter identification. The foundation types also affected the identification results due to different SFS interactions. The identification accuracy was reduced as the nonlinear effects due to damage increased. *MRFM could characterize the nonlinear behavior of the interstory restoring forces. The localized damage could be quantified by measuring dissipated energy of each floor. The most severe damage in the superstructure was observed with the fixed foundation. Second, the responses of a full-scale suspension bridge in a ship-bridge collision accident were analyzed to characterize the dynamic properties of the bridge. Three parametric and non-parametric identification methods, NExT-ERA, PCA and ICA were used to process the bridge response data to evaluate the performance of mode decomposition of these methods for traffic, no-traffic, and collision loading conditions. The PCA and ICA identification results were compared with those of NExT-ERA method for different excitation, response types, system damping and sensor spatial resolution. The major findings from the ship-bridge collision study include: *PCA was able to characterize the mode shapes and modal coordinates for velocity and displacement responses. The results using the acceleration were less accurate. The inter-channel correlation and sensor spatial resolution had significant effects on the mode decomposition accuracy. *ICA showed the lowest performance in this mode decomposition study. It was observed that the excitation type and system characteristics significantly affected the ICA accuracy

    Expression cartography of human tissues using self organizing maps

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    Background: The availability of parallel, high-throughput microarray and sequencing experiments poses a challenge how to best arrange and to analyze the obtained heap of multidimensional data in a concerted way. Self organizing maps (SOM), a machine learning method, enables the parallel sample- and gene-centered view on the data combined with strong visualization and second-level analysis capabilities. The paper addresses aspects of the method with practical impact in the context of expression analysis of complex data sets.
Results: The method was applied to generate a SOM characterizing the whole genome expression profiles of 67 healthy human tissues selected from ten tissue categories (adipose, endocrine, homeostasis, digestion, exocrine, epithelium, sexual reproduction, muscle, immune system and nervous tissues). SOM mapping reduces the dimension of expression data from ten thousands of genes to a few thousands of metagenes where each metagene acts as representative of a minicluster of co-regulated single genes. Tissue-specific and common properties shared between groups of tissues emerge as a handful of localized spots in the tissue maps collecting groups of co-regulated and co-expressed metagenes. The functional context of the spots was discovered using overrepresentation analysis with respect to pre-defined gene sets of known functional impact. We found that tissue related spots typically contain enriched populations of gene sets well corresponding to molecular processes in the respective tissues. Analysis techniques normally used at the gene-level such as two-way hierarchical clustering provide a better signal-to-noise ratio and a better representativeness of the method if applied to the metagenes. Metagene-based clustering analyses aggregate the tissues into essentially three clusters containing nervous, immune system and the remaining tissues. 
Conclusions: The global view on the behavior of a few well-defined modules of correlated and differentially expressed genes is more intuitive and more informative than the separate discovery of the expression levels of hundreds or thousands of individual genes. The metagene approach is less sensitive to a priori selection of genes. It can detect a coordinated expression pattern whose components would not pass single-gene significance thresholds and it is able to extract context-dependent patterns of gene expression in complex data sets.
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