Ontological foundations for structural conceptual models

In this thesis, we aim at contributing to the theory of conceptual modeling and ontology representation. Our main objective here is to provide ontological foundations for the most fundamental concepts in conceptual modeling. These foundations comprise a number of ontological theories, which are built on established work on philosophical ontology, cognitive psychology, philosophy of language and linguistics. Together these theories amount to a system of categories and formal relations known as a foundational ontolog

Computerization of workflows, guidelines and care pathways: a review of implementation challenges for process-oriented health information systems

There is a need to integrate the various theoretical frameworks and formalisms for modeling clinical guidelines, workflows, and pathways, in order to move beyond providing support for individual clinical decisions and toward the provision of process-oriented, patient-centered, health information systems (HIS). In this review, we analyze the challenges in developing process-oriented HIS that formally model guidelines, workflows, and care pathways. A qualitative meta-synthesis was performed on studies published in English between 1995 and 2010 that addressed the modeling process and reported the exposition of a new methodology, model, system implementation, or system architecture. Thematic analysis, principal component analysis (PCA) and data visualisation techniques were used to identify and cluster the underlying implementation ‘challenge’ themes. One hundred and eight relevant studies were selected for review. Twenty-five underlying ‘challenge’ themes were identified. These were clustered into 10 distinct groups, from which a conceptual model of the implementation process was developed. We found that the development of systems supporting individual clinical decisions is evolving toward the implementation of adaptable care pathways on the semantic web, incorporating formal, clinical, and organizational ontologies, and the use of workflow management systems. These architectures now need to be implemented and evaluated on a wider scale within clinical settings

Clinical decision support system for point of care use--ontology-driven design and software implementation

OBJECTIVES: The objective of this research was to design a clinical decision support system (CDSS) that supports heterogeneous clinical decision problems and runs on multiple computing platforms. Meeting this objective required a novel design to create an extendable and easy to maintain clinical CDSS for point of care support. The proposed solution was evaluated in a proof of concept implementation. METHODS: Based on our earlier research with the design of a mobile CDSS for emergency triage we used ontology-driven design to represent essential components of a CDSS. Models of clinical decision problems were derived from the ontology and they were processed into executable applications during runtime. This allowed scaling applications' functionality to the capabilities of computing platforms. A prototype of the system was implemented using the extended client-server architecture and Web services to distribute the functions of the system and to make it operational in limited connectivity conditions. RESULTS: The proposed design provided a common framework that facilitated development of diversified clinical applications running seamlessly on a variety of computing platforms. It was prototyped for two clinical decision problems and settings (triage of acute pain in the emergency department and postoperative management of radical prostatectomy on the hospital ward) and implemented on two computing platforms--desktop and handheld computers. CONCLUSIONS: The requirement of the CDSS heterogeneity was satisfied with ontology-driven design. Processing of application models described with the help of ontological models allowed having a complex system running on multiple computing platforms with different capabilities. Finally, separation of models and runtime components contributed to improved extensibility and maintainability of the system

The Landscape of Ontology Reuse Approaches

Ontology reuse aims to foster interoperability and facilitate knowledge reuse. Several approaches are typically evaluated by ontology engineers when bootstrapping a new project. However, current practices are often motivated by subjective, case-by-case decisions, which hamper the definition of a recommended behaviour. In this chapter we argue that to date there are no effective solutions for supporting developers' decision-making process when deciding on an ontology reuse strategy. The objective is twofold: (i) to survey current approaches to ontology reuse, presenting motivations, strategies, benefits and limits, and (ii) to analyse two representative approaches and discuss their merits

Ontology Building: An Integrative View of Methodologies

Ontologies are being developed and used in many disciplines now a day and they have become a key tool of data integration and knowledge representation in different domains of interest. The ontology building process identifies the stages through which the ontology should go through during its development. There is a certain set of activities to be performed in each stage of the ontology development process and different methodologies have been proposed by researchers for formalizing the different stages. The present paper investigates the most representative methodologies used in the ontology development to look at the different activities that are performed during the process of ontology development. The paper further attempts to provide an integrative view of the most representative methodologies used in the ontology development to look at the set of different activities that can be performed during the process of the ontology development. DOI: 10.17762/ijritcc2321-8169.15076