New Research in Children with Neurodevelopmental Disorders

This book collects recent research in the field of care for neurodevelopmental disorders, emphasizing transdisciplinary work in clinical, educational and family contexts. It presents an opportunity to learn about the impact of participation on children and adolescents with neurodevelopmental disorders. Mainly, new therapeutic approaches are presented in children and adolescents with autism spectrum disorder, attention-deficit/hyperactivity disorder, or motor coordination disorders

Psychometric evaluation of the quick screening procedure for referral to occupational therapy (QSPOT) for five year olds with and without barries to learning

A research report submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in partial fulfilment of the requirements for the degree of Master of Science in Occupational Therapy. Johannesburg, 2016Designed by a group of South African Occupational Therapists, the Quick Screening Procedure for Referral to Occupational Therapy (QSPOT) screens motor, praxis and sensory-perceptual performance skills related to intrinsic barriers to learning in children aged between 4 and 6 years. The aim of this study was to determine the sensitivity and specificity of the QSPOT in identifying intrinsic barriers to learning in 5 year olds, as well as the concurrent criterion validity of the QSPOT compared to the Movement ABC-2, and the Developmental Test of Visual-Motor Integration, 6th Edition (VMI and Visual Perception subtests). Eighty-three learners in mainstream schools and Learners with Special Education Needs schools were assessed with all three tests. Acceptable specificity was found for the QSPOT; however, sensitivity was unacceptably low. Adequate concurrent criterion validity was found between the QSPOT Total Score and the Movement ABC-2 Total Score, as well as between the QSPOT and DTVMI-VMI for Age-band 1 (5 years 0 months to 5 years 5 months). However, inadequate concurrent criterion validity was found for the QSPOT for Age-band 2 (5 years 6 months to 5 years 11 months). Key words: Intrinsic barriers to learning, motor and praxis performance skills, sensory-perceptual performance skills, screening, screening procedures, sensitivity, specificity, concurrent criterion validityMT201

BRB Newsletter, Fall 2013

This issue features: Updates - Featured Story: Our New Home, American Society of Biomechanics Meting, Nonlinear Workshop 2013, European Nonlinear Workshop, and Staff Updates; Projects - VA Peripheral Arterial Disease, Motor Development, Optical Topography System, Effects of Virtual Reality, Virtual Reality, Robotic Surgery, Sports Medicine, Amputee, Proof of Concept Grant, Lateral Stepping, The Marriage of Music and Math, Chronic Obstructive Pulmonary Disease, Balance, NASA Grant, Back Pain Research, and Faculty Research International Grants. Other Content - Other Visitors/Tours, Student Awards, Travels, and Campaign for Nebraska.https://digitalcommons.unomaha.edu/nbcfnewsletter/1010/thumbnail.jp

A standard of care for individuals with PIK3CA ‐related disorders: an international expert consensus statement

Growth promoting variants in PIK3CA cause a spectrum of developmental disorders, depending on the developmental timing of the mutation and tissues involved. These phenotypically heterogeneous entities have been grouped as PIK3CA-Related Overgrowth Spectrum disorders (PROS). Deep sequencing technologies have facilitated detection of low-level mosaic, often necessitating testing of tissues other than blood. Since clinical management practices vary considerably among healthcare professionals and services across different countries, a consensus on management guidelines is needed. Clinical heterogeneity within this spectrum leads to challenges in establishing management recommendations, which must be based on patient-specific considerations. Moreover, as most of these conditions are rare, affected families may lack access to the medical expertise that is needed to help address the multi-system and often complex medical issues seen with PROS. In March 2019, macrocephaly-capillary malformation (M-CM) patient organizations hosted an expert meeting in Manchester, United Kingdom, to help address these challenges with regards to M-CM syndrome. We have expanded the scope of this project to cover PROS and developed this consensus statement on the preferred approach for managing affected individuals based on our current knowledge