Process Control Parameters Evaluation Using Discrete Event Simulation for Business Process Optimization

The quest for manufacturing process improvement and higher levels of customer satisfaction mandates that organizations must be equipped with advanced tools and techniques in order to respond towards ever changing internal and external customer demands by maintaining the optimal process performance, lower cost and higher profit levels. A manufacturing process can be defined as a collection of activities designed to produce a specific output for a particular customer or market. To achieve internal and external objectives, significant process parameters must be identified and evaluated to optimize the process performance. This even becomes more important to deal with fierce competition and ever changing customer demands. This paper illustrates an integrated approach using design of experiments techniques and discrete event simulation (Simul8) to understand and optimize the system dynamic based on operational control parameter evaluation and their boundary conditions. Further, the proposed model is validated using a real world manufacturing process case study to optimize the manufacturing process performance. Discrete event simulation tool is used to mimic the real world scenario, which provides a flexible and powerful way to comprehensively understand the manufacturing process variations and allows controlled 'What-If´ analysis based on design of experiments approach. Finally, this paper discusses the potential applications of the proposed methodology in the cable industry in order to optimize the cable manufacturing process by regulating the operational control parameters such as dealing with various product configurations with different equipment settings, different product flows and work in process (WIP) space limitations

Event-Based Implementation of Fractional Order IMC Controllers for Simple FOPDT Processes

Fractional order calculus has been used to generalize various types of controllers, including internal model controllers (IMC). The focus of this manuscript is towards fractional order IMCs for first order plus dead-time (FOPDT) processes, including delay and lag dominant ones. The design is novel at it is based on a new approximation approach, the non-rational transfer function method. This allows for a more accurate approximation of the process dead-time and ensures an improved closed loop response. The main problem with fractional order controllers is concerned with their implementation as higher order transfer functions. In cases where central processing unit CPU, bandwidth allocation, and energy usage are limited, resources need to be efficiently managed. This can be achieved using an event-based implementation. The novelty of this paper resides in such an event-based algorithm for fractional order IMC (FO-IMC) controllers. Numerical results are provided for lag and delay dominant FOPDT processes. For comparison purposes, an integer order PI controller, tuned according to the same performance specifications as the FO-IMC, is also implemented as an event-based control strategy. The numerical results show that the proposed event-based implementation for the FO-IMC controller is suitable and provides for a smaller computational effort, thus being more suitable in various industrial applications

Integration of a Flat Holonic Form in an HLA Environment

International audienceManagers need to create and sustain internal systems and controls to ensure that their customer focused strategies are being implemented. Companies are currently in a spiral of permanent optimization. Accordingly, many companies turn to their core activity. In this framework, one notices the development of the concept of “industrial partnership”. In this context and to control the customer–supplier relationships (CSR), we proposed a self-organized control model in which all partner entities (customers/suppliers) negotiate to guarantee good quality connections between customers and suppliers. This means meeting customer expectations as closely as possible and respecting supplier capacities. In this proposal, self-organized control is characterized more precisely by an organizational architecture of the flat holonic form type. This flat holonic form is based on the concept of autonomous control entity (ACE). The holonic architecture, the behaviour of an ACE, the interaction mechanisms between ACEs and the self-evaluation supplier process are presented, and then the modelling of ACEs using discrete event system specification (DEVS) is described. An implementation of the simulation of such a system was done via a distributed simulation environment high level architecture (HLA). A case study illustrating the proposed approach is presented

Statistical tools for transgene copy number estimation based on real-time PCR

Background As compared with traditional transgene copy number detection technologies such as Southern blot analysis, real-time PCR provides a fast, inexpensive and high-throughput alternative. However, the real-time PCR based transgene copy number estimation tends to be ambiguous and subjective stemming from the lack of proper statistical analysis and data quality control to render a reliable estimation of copy number with a prediction value. Despite the recent progresses in statistical analysis of real-time PCR, few publications have integrated these advancements in real-time PCR based transgene copy number determination. Results Three experimental designs and four data quality control integrated statistical models are presented. For the first method, external calibration curves are established for the transgene based on serially-diluted templates. The Ct number from a control transgenic event and putative transgenic event are compared to derive the transgene copy number or zygosity estimation. Simple linear regression and two group T-test procedures were combined to model the data from this design. For the second experimental design, standard curves were generated for both an internal reference gene and the transgene, and the copy number of transgene was compared with that of internal reference gene. Multiple regression models and ANOVA models can be employed to analyze the data and perform quality control for this approach. In the third experimental design, transgene copy number is compared with reference gene without a standard curve, but rather, is based directly on fluorescence data. Two different multiple regression models were proposed to analyze the data based on two different approaches of amplification efficiency integration. Our results highlight the importance of proper statistical treatment and quality control integration in real-time PCR-based transgene copy number determination. Conclusion These statistical methods allow the real-time PCR-based transgene copy number estimation to be more reliable and precise with a proper statistical estimation. Proper confidence intervals are necessary for unambiguous prediction of trangene copy number. The four different statistical methods are compared for their advantages and disadvantages. Moreover, the statistical methods can also be applied for other real-time PCR-based quantification assays including transfection efficiency analysis and pathogen quantification

Statistical tools for transgene copy number estimation based on real-time PCR

Background As compared with traditional transgene copy number detection technologies such as Southern blot analysis, real-time PCR provides a fast, inexpensive and high-throughput alternative. However, the real-time PCR based transgene copy number estimation tends to be ambiguous and subjective stemming from the lack of proper statistical analysis and data quality control to render a reliable estimation of copy number with a prediction value. Despite the recent progresses in statistical analysis of real-time PCR, few publications have integrated these advancements in real-time PCR based transgene copy number determination. Results Three experimental designs and four data quality control integrated statistical models are presented. For the first method, external calibration curves are established for the transgene based on serially-diluted templates. The Ct number from a control transgenic event and putative transgenic event are compared to derive the transgene copy number or zygosity estimation. Simple linear regression and two group T-test procedures were combined to model the data from this design. For the second experimental design, standard curves were generated for both an internal reference gene and the transgene, and the copy number of transgene was compared with that of internal reference gene. Multiple regression models and ANOVA models can be employed to analyze the data and perform quality control for this approach. In the third experimental design, transgene copy number is compared with reference gene without a standard curve, but rather, is based directly on fluorescence data. Two different multiple regression models were proposed to analyze the data based on two different approaches of amplification efficiency integration. Our results highlight the importance of proper statistical treatment and quality control integration in real-time PCR-based transgene copy number determination. Conclusion These statistical methods allow the real-time PCR-based transgene copy number estimation to be more reliable and precise with a proper statistical estimation. Proper confidence intervals are necessary for unambiguous prediction of trangene copy number. The four different statistical methods are compared for their advantages and disadvantages. Moreover, the statistical methods can also be applied for other real-time PCR-based quantification assays including transfection efficiency analysis and pathogen quantification

ADAPTIVE MODEL BASED COMBUSTION PHASING CONTROL FOR MULTI FUEL SPARK IGNITION ENGINES

This research describes a physics-based control-oriented feed-forward model, combined with cylinder pressure feedback, to regulate combustion phasing in a spark-ignition engine operating on an unknown mix of fuels. This research may help enable internal combustion engines that are capable of on-the-fly adaptation to a wide range of fuels. These engines could; (1) facilitate a reduction in bio-fuel processing, (2) encourage locally-appropriate bio-fuels to reduce transportation, (3) allow new fuel formulations to enter the market with minimal infrastructure, and (4) enable engine adaptation to pump-to-pump fuel variations. These outcomes will help make bio-fuels cost-competitive with other transportation fuels, lessen dependence on traditional sources of energy, and reduce greenhouse gas emissions from automobiles; all of which are pivotal societal issues. Spark-ignition engines are equipped with a large number of control actuators to satisfy fuel economy targets and maintain regulated emissions compliance. The increased control flexibility also allows for adaptability to a wide range of fuel compositions, while maintaining efficient operation when input fuel is altered. Ignition timing control is of particular interest because it is the last control parameter prior to the combustion event, and significantly influences engine efficiency and emissions. Although Map-based ignition timing control and calibration routines are state of art, they become cumbersome when the number of control degrees of freedom increases are used in the engine. The increased system complexity motivates the use of model-based methods to minimize product development time and ensure calibration flexibility when the engine is altered during the design process. A closed loop model based ignition timing control algorithm is formulated with: 1) a feed forward fuel type sensitive combustion model to predict combustion duration from spark to 50% mass burned; 2) two virtual fuel property observers for octane number and laminar flame speed feedback; 3) an adaptive combustion phasing target model that is able to self-calibrate for wide range of fuel sources input. The proposed closed loop algorithm is experimentally validated in real time on the dynamometer. Satisfactory results are observed and conclusions are made that the closed loop approach is able to regulate combustion phasing for multi fuel adaptive SI engines

Trajectory Prediction with Event-Based Cameras for Robotics Applications

This thesis presents the study, analysis, and implementation of a framework to perform trajectory prediction using an event-based camera for robotics applications. Event-based perception represents a novel computation paradigm based on unconventional sensing technology that holds promise for data acquisition, transmission, and processing at very low latency and power consumption, crucial in the future of robotics. An event-based camera, in particular, is a sensor that responds to light changes in the scene, producing an asynchronous and sparse output over a wide illumination dynamic range. They only capture relevant spatio-temporal information - mostly driven by motion - at high rate, avoiding the inherent redundancy in static areas of the field of view. For such reasons, this device represents a potential key tool for robots that must function in highly dynamic and/or rapidly changing scenarios, or where the optimisation of the resources is fundamental, like robots with on-board systems. Prediction skills are something humans rely on daily - even unconsciously - for instance when driving, playing sports, or collaborating with other people. In the same way, predicting the trajectory or the end-point of a moving target allows a robot to plan for appropriate actions and their timing in advance, interacting with it in many different manners. Moreover, prediction is also helpful for compensating robot internal delays in the perception-action chain, due for instance to limited sensors and/or actuators. The question I addressed in this work is whether event-based cameras are advantageous or not in trajectory prediction for robotics. In particular, if classical deep learning architecture used for this task can accommodate for event-based data, working asynchronously, and which benefit they can bring with respect to standard cameras. The a priori hypothesis is that being the sampling of the scene driven by motion, such a device would allow for more meaningful information acquisition, improving the prediction accuracy and processing data only when needed - without any information loss or redundant acquisition. To test the hypothesis, experiments are mostly carried out using the neuromorphic iCub, a custom version of the iCub humanoid platform that mounts two event-based cameras in the eyeballs, along with standard RGB cameras. To further motivate the work on iCub, a preliminary step is the evaluation of the robot's internal delays, a value that should be compensated by the prediction to interact in real-time with the object perceived. The first part of this thesis sees the implementation of the event-based framework for prediction, to answer the question if Long Short-Term Memory neural networks, the architecture used in this work, can be combined with event-based cameras. The task considered is the handover Human-Robot Interaction, during which the trajectory of the object in the human's hand must be inferred. Results show that the proposed pipeline can predict both spatial and temporal coordinates of the incoming trajectory with higher accuracy than model-based regression methods. Moreover, fast recovery from failure cases and adaptive prediction horizon behavior are exhibited. Successively, I questioned how much the event-based sampling approach can be convenient with respect to the classical fixed-rate approach. The test case used is the trajectory prediction of a bouncing ball, implemented with the pipeline previously introduced. A comparison between the two sampling methods is analysed in terms of error for different working rates, showing how the spatial sampling of the event-based approach allows to achieve lower error and also to adapt the computational load dynamically, depending on the motion in the scene. Results from both works prove that the merging of event-based data and Long Short-Term Memory networks looks promising for spatio-temporal features prediction in highly dynamic tasks, and paves the way to further studies about the temporal aspect and to a wide range of applications, not only robotics-related. Ongoing work is now focusing on the robot control side, finding the best way to exploit the spatio-temporal information provided by the predictor and defining the optimal robot behavior. Future work will see the shift of the full pipeline - prediction and robot control - to a spiking implementation. First steps in this direction have been already made thanks to a collaboration with a group from the University of Zurich, with which I propose a closed-loop motor controller implemented on a mixed-signal analog/digital neuromorphic processor, emulating a classical PID controller by means of spiking neural networks

Improved vector control methods for brushless double fed induction generator during inductive load and fault conditions

A Brushless Double-Fed Induction Generator (BDFIG) has shown tremendous success in wind turbines due to its robust brushless design, less maintenance, smooth operation, and variable speed characteristics. These generators are composed of two back-to-back voltage source converters, a Grid Side Converter (GSC) and a Rotor Side Converter (RSC). Existing control techniques use a “trial and error” method that results in a poor dynamic response in machine parameters during the absence of load. The RSC control is used for reactive current control during the inductive load insertion. However, it is more suitable for stabilizing steady-state behaviour, but it suffers from slow response and introduces a double fundamental frequency component to the Point of Common Coupling (PCC) voltage. In addition, generally, a Low Voltage Ride Through (LVRT) fault is detected using a hysteresis comparison of the power winding voltage. The LVRT capability is provided by using fixed reference values to control the winding current. This approach results in an erroneous response, sub-optimal control of voltage drops at PCC, and false alarms during transient conditions. This thesis aims to solve the mentioned issues by using an improved vector control method. Internal Model Control (IMC) based Proportional-Integral (PI) gains calculation is used for GSC and RSC. These are controlled to enhance the transient response and power quality during no-load, inductive load, and fault conditions. Firstly, a GSC-based vector control method is proposed to suppress the PCC voltage fluctuations when a large inductive load is suddenly connected. The proposed technique is based on an analytical model of the transient behaviour of the voltage drop at the PCC. To block a double fundamental frequency component as a result of reactive current compensation, a notch filter is designed. Secondly, an RSC-based vector control method is proposed using an analytical model of the voltage drop caused by a short circuit. Moreover, using a fuzzy logic controller, the proposed technique employs the voltage frequency in addition to the power winding voltage magnitude to detect LVRT conditions. The analytical model helps in reducing the power winding voltage drop while the fuzzy logic controller leads to better response and faster detection of faults. However, the reference value for reactive current compensation is analysed using an analytical model of the voltage drop at the PCC in the event of a short-circuit fault. The results obtained from MATLAB/Simulink show that the GSC-based vector control method technique can effectively reduce about 10% voltage drop at PCCs. Total Harmonics Distortion (THD) is improved to 22.3% by notch filter in comparison with an existing technique such as instantaneous reactive power theory. The RSC-based vector control method can achieve up to 11% voltage drop reduction and improve the THD by 12% compared to recent synchronous control and flux tracking methods