Seizure detection using EEG and ECG signals for computer-based monitoring, analysis and management of epileptic patients

This is the accepted manuscript version of the following article: Iosif Mporas, “Seizure detection using EEG and ECG signals for computer-based monitoring, analysis and management of epileptic patients”, Expert Systems with Applications, Vol. 42(6), December 2014. The final published version is available at: http://www.sciencedirect.com/science/article/pii/S0957417414007763?via%3Dihub © 2014 Elsevier Ltd. All rights reserved.In this paper a seizure detector using EEG and ECG signals, as a module of a healthcare system, is presented. Specifically, the module is based on short-time analysis with time-domain and frequency-domain features and classification using support vector machines. The seizure detection module was evaluated on three subjects with diagnosed idiopathic generalized epilepsy manifested with absences. The achieved seizure detection accuracy was approximately 90% for all evaluated subjects. Feature ranking investigation and evaluation of the seizure detection module using subsets of features showed that the feature vector composed of approximately the 65%-best ranked parameters provides a good trade-off between computational demands and accuracy. This configurable architecture allows the seizure detection module to operate as part of a healthcare system in offline mode as well as in online mode, where real-time performance is needed.Peer reviewe

EEG signal classification using wavelet feature extraction and neural networks

Decision support systems have been utilised since 1960, providing physicians with fast and accurate means towards more accurate diagnoses and increased tolerance when handling missing or incomplete data. This paper describes the application of neural network models for classification of electroencephalogram (EEG) signals. Decision making was performed in two stages: initially, a feature extraction scheme using the wavelet transform (WT) has been applied and then a learning-based algorithm classifier performed the classification. The performance of the neural model was evaluated in terms of training performance and classification accuracies and the results confirmed that the proposed scheme has potential in classifying the EEG signals

A hybrid unsupervised approach toward EEG epileptic spikes detection

Epileptic spikes are complementary sources of information in EEG to diagnose and localize the origin of epilepsy. However, not only is visual inspection of EEG labor intensive, time consuming, and prone to human error, but it also needs long-term training to acquire the level of skill required for identifying epileptic discharges. Therefore, computer-aided approaches were employed for the purpose of saving time and increasing the detection and source localization accuracy. One of the most important artifacts that may be confused as an epileptic spike, due to morphological resemblance, is eye blink. Only a few studies consider removal of this artifact prior to detection, and most of them used either visual inspection or computer-aided approaches, which need expert supervision. Consequently, in this paper, an unsupervised and EEG-based system with embedded eye blink artifact remover is developed to detect epileptic spikes. The proposed system includes three stages: eye blink artifact removal, feature extraction, and classification. Wavelet transform was employed for both artifact removal and feature extraction steps, and adaptive neuro-fuzzy inference system for classification purpose. The proposed method is verified using a publicly available EEG dataset. The results show the efficiency of this algorithm in detecting epileptic spikes using low-resolution EEG with least computational complexity, highest sensitivity, and lesser human interaction compared to similar studies. Moreover, since epileptic spike detection is a vital component of epilepsy source localization, therefore this algorithm can be utilized for EEG-based pre-surgical evaluation of epilepsy

Data mining an EEG dataset with an emphasis on dimensionality reduction

The human brain is obviously a complex system, and exhibits rich spatiotemporal dynamics. Among the non-invasive techniques for probing human brain dynamics, electroencephalography (EEG) provides a direct measure of cortical activity with millisecond temporal resolution. Early attempts to analyse EEG data relied on visual inspection of EEG records. Since the introduction of EEG recordings, the volume of data generated from a study involving a single patient has increased exponentially. Therefore, automation based on pattern classification techniques have been applied with considerable success. In this study, a multi-step approach for the classification of EEG signal has been adopted. We have analysed sets of EEG time series recording from healthy volunteers with open eyes and intracranial EEG recordings from patients with epilepsy during ictal (seizure) periods. In the present work, we have employed a discrete wavelet transform to the EEG data in order to extract temporal information in the form of changes in the frequency domain over time - that is they are able to extract non-stationary signals embedded in the noisy background of the human brain. Principal components analysis (PCA) and rough sets have been used to reduce the data dimensionality. A multi-classifier scheme consists of LVQ2.1 neural networks have been developed for the classification task. The experimental results validated the proposed methodology

Forecasting Spanish economic activity in times of COVID-19 by means of the RT-LEI and machine learning techniques.

The main aim of this paper is to analyse and estimate the behaviour of the Spanish economic activity in the next 12 months, by means of a Real-Time Leading Economic Indicator (RT-LEI), based on Google Trends, and the real GDP. We apply methodologies based on fractional integration and cointegration to measure the degree of persistence and to examine the long-term relationship. Finally, we carry out a forecast using a Machine Learning model based on an Artificial Neural Network. Our results indicate that the Spanish economy will experience a contraction in 1Q-21 and will require strong measures to reverse the situation and recover the original trend.pre-print334 K

Terrorism Event Classification Using Fuzzy Inference Systems

Terrorism has led to many problems in Thai societies, not only property damage but also civilian casualties. Predicting terrorism activities in advance can help prepare and manage risk from sabotage by these activities. This paper proposes a framework focusing on event classification in terrorism domain using fuzzy inference systems (FISs). Each FIS is a decision-making model combining fuzzy logic and approximate reasoning. It is generated in five main parts: the input interface, the fuzzification interface, knowledge base unit, decision making unit and output defuzzification interface. Adaptive neuro-fuzzy inference system (ANFIS) is a FIS model adapted by combining the fuzzy logic and neural network. The ANFIS utilizes automatic identification of fuzzy logic rules and adjustment of membership function (MF). Moreover, neural network can directly learn from data set to construct fuzzy logic rules and MF implemented in various applications. FIS settings are evaluated based on two comparisons. The first evaluation is the comparison between unstructured and structured events using the same FIS setting. The second comparison is the model settings between FIS and ANFIS for classifying structured events. The data set consists of news articles related to terrorism events in three southern provinces of Thailand. The experimental results show that the classification performance of the FIS resulting from structured events achieves satisfactory accuracy and is better than the unstructured events. In addition, the classification of structured events using ANFIS gives higher performance than the events using only FIS in the prediction of terrorism events.Comment: IEEE Publication format, ISSN 1947 5500, http://sites.google.com/site/ijcsis

Epilepsy

With the vision of including authors from different parts of the world, different educational backgrounds, and offering open-access to their published work, InTech proudly presents the latest edited book in epilepsy research, Epilepsy: Histological, electroencephalographic, and psychological aspects. Here are twelve interesting and inspiring chapters dealing with basic molecular and cellular mechanisms underlying epileptic seizures, electroencephalographic findings, and neuropsychological, psychological, and psychiatric aspects of epileptic seizures, but non-epileptic as well