Weighted Heuristic Ensemble of Filters

Feature selection has become increasingly important in data mining in recent years due to the rapid increase in the dimensionality of big data. However, the reliability and consistency of feature selection methods (filters) vary considerably on different data and no single filter performs consistently well under various conditions. Therefore, feature selection ensemble has been investigated recently to provide more reliable and effective results than any individual one but all the existing feature selection ensemble treat the feature selection methods equally regardless of their performance. In this paper, we present a novel framework which applies weighted feature selection ensemble through proposing a systemic way of adding different weights to the feature selection methods-filters. Also, we investigate how to determine the appropriate weight for each filter in an ensemble. Experiments based on ten benchmark datasets show that theoretically and intuitively adding more weight to ‘good filters’ should lead to better results but in reality it is very uncertain. This assumption was found to be correct for some examples in our experiment. However, for other situations, filters which had been assumed to perform well showed bad performance leading to even worse results. Therefore adding weight to filters might not achieve much in accuracy terms, in addition to increasing complexity, time consumption and clearly decreasing the stability

A multi-filter enhanced genetic ensemble system for gene selection and sample classification of microarray data

Background: Feature selection techniques are critical to the analysis of high dimensional datasets. This is especially true in gene selection from microarray data which are commonly with extremely high feature-to-sample ratio. In addition to the essential objectives such as to reduce data noise, to reduce data redundancy, to improve sample classification accuracy, and to improve model generalization property, feature selection also helps biologists to focus on the selected genes to further validate their biological hypotheses.Results: In this paper we describe an improved hybrid system for gene selection. It is based on a recently proposed genetic ensemble (GE) system. To enhance the generalization property of the selected genes or gene subsets and to overcome the overfitting problem of the GE system, we devised a mapping strategy to fuse the goodness information of each gene provided by multiple filtering algorithms. This information is then used for initialization and mutation operation of the genetic ensemble system.Conclusion: We used four benchmark microarray datasets (including both binary-class and multi-class classification problems) for concept proving and model evaluation. The experimental results indicate that the proposed multi-filter enhanced genetic ensemble (MF-GE) system is able to improve sample classification accuracy, generate more compact gene subset, and converge to the selection results more quickly. The MF-GE system is very flexible as various combinations of multiple filters and classifiers can be incorporated based on the data characteristics and the user preferences. <br /

An agent-based hybrid system for microarray data analysis

This article reports our experience in agent-based hybrid construction for microarray data analysis. The contributions are twofold: We demonstrate that agent-based approaches are suitable for building hybrid systems in general, and that a genetic ensemble system is appropriate for microarray data analysis in particular. Created using an agent-based framework, this genetic ensemble system for microarray data analysis excels in both sample classification accuracy and gene selection reproducibility.<br /

Heuristic ensembles of filters for accurate and reliable feature selection

Feature selection has become increasingly important in data mining in recent years. However, the accuracy and stability of feature selection methods vary considerably when used individually, and yet no rule exists to indicate which one should be used for a particular dataset. Thus, an ensemble method that combines the outputs of several individual feature selection methods appears to be a promising approach to address the issue and hence is investigated in this research. This research aims to develop an effective ensemble that can improve the accuracy and stability of the feature selection. We proposed a novel heuristic ensemble of filters (HEF). It combines two types of filters: subset filters and ranking filters with a heuristic consensus algorithm in order to utilise the strength of each type. The ensemble is tested on ten benchmark datasets and its performance is evaluated by two stability measures and three classifiers. The experimental results demonstrate that HEF improves the stability and accuracy of the selected features and in most cases outperforms the other ensemble algorithms, individual filters and the full feature set. The research on the HEF algorithm is extended in several dimensions; including more filter members, three novel schemes of mean rank aggregation with partial lists, and three novel schemes for a weighted heuristic ensemble of filters. However, the experimental results demonstrate that adding weight to filters in HEF does not achieve the expected improvement in accuracy, but increases time and space complexity, and clearly decreases stability. Therefore, the core ensemble algorithm (HEF) is demonstrated to be not just simpler but also more reliable and consistent than the later more complicated and weighted ensembles. In addition, we investigated how to use data in feature selection, using ALL or PART of it. Systematic experiments with thirty five synthetic and benchmark real-world datasets were carried out

An Ensemble Framework Coping with Instability in the Gene Selection Process

[EN] This paper proposes an ensemble framework for gene selection, which is aimed at addressing instability problems presented in the gene filtering task. The complex process of gene selection from gene expression data faces different instability problems from the informative gene subsets found by different filter methods. This makes the identification of significant genes by the experts difficult. The instability of results can come from filter methods, gene classifier methods, different datasets of the same disease and multiple valid groups of biomarkers. Even though there is a wide number of proposals, the complexity imposed by this problem remains a challenge today. This work proposes a framework involving five stages of gene filtering to discover biomarkers for diagnosis and classification tasks. This framework performs a process of stable feature selection, facing the problems above and, thus, providing a more suitable and reliable solution for clinical and research purposes. Our proposal involves a process of multistage gene filtering, in which several ensemble strategies for gene selection were added in such a way that different classifiers simultaneously assess gene subsets to face instability. Firstly, we apply an ensemble of recent gene selection methods to obtain diversity in the genes found (stability according to filter methods). Next, we apply an ensemble of known classifiers to filter genes relevant to all classifiers at a time (stability according to classification methods). The achieved results were evaluated in two different datasets of the same disease (pancreatic ductal adenocarcinoma), in search of stability according to the disease, for which promising results were achieved

Exploiting the ensemble paradigm for stable feature selection: A case study on high-dimensional genomic data

Ensemble classification is a well-established approach that involves fusing the decisions of multiple predictive models. A similar “ensemble logic” has been recently applied to challenging feature selection tasks aimed at identifying the most informative variables (or features) for a given domain of interest. In this work, we discuss the rationale of ensemble feature selection and evaluate the effects and the implications of a specific ensemble approach, namely the data perturbation strategy. Basically, it consists in combining multiple selectors that exploit the same core algorithm but are trained on different perturbed versions of the original data. The real potential of this approach, still object of debate in the feature selection literature, is here investigated in conjunction with different kinds of core selection algorithms (both univariate and multivariate). In particular, we evaluate the extent to which the ensemble implementation improves the overall performance of the selection process, in terms of predictive accuracy and stability (i.e., robustness with respect to changes in the training data). Furthermore, we measure the impact of the ensemble approach on the final selection outcome, i.e. on the composition of the selected feature subsets. The results obtained on ten public genomic benchmarks provide useful insight on both the benefits and the limitations of such ensemble approach, paving the way to the exploration of new and wider ensemble schemes

Filter-wrapper combination and embedded feature selection for gene expression data

Biomedical and bioinformatics datasets are generally large in terms of their number of features - and include redundant and irrelevant features, which affect the effectiveness and efficiency of classification of these datasets. Several different features selection methods have been utilised in various fields, including bioinformatics, to reduce the number of features. This study utilised Filter-Wrapper combination and embedded (LASSO) feature selection methods on both high and low dimensional datasets before classification was performed. The results illustrate that the combination of filter and wrapper feature selection to create a hybrid form of feature selection provides better performance than using filter only. In addition, LASSO performed better on high dimensional data

Ensembles of wrappers for automated feature selection in fish age classification

In feature selection, the most important features must be chosen so as to decrease the number thereof while retaining their discriminatory information. Within this context, a novel feature selection method based on an ensemble of wrappers is proposed and applied for automatically select features in fish age classification. The effectiveness of this procedure using an Atlantic cod database has been tested for different powerful statistical learning classifiers. The subsets based on few features selected, e.g. otolith weight and fish weight, are particularly noticeable given current biological findings and practices in fishery research and the classification results obtained with them outperforms those of previous studies in which a manual feature selection was performed.Peer ReviewedPostprint (author's final draft