Wearable Platform for Automatic Recognition of Parkinson Disease by Muscular Implication Monitoring

The need for diagnostic tools for the characterization of progressive movement disorders - as the Parkinson Disease (PD) - aiming to early detect and monitor the pathology is getting more and more impelling. The parallel request of wearable and wireless solutions, for the real-time monitoring in a non-controlled environment, has led to the implementation of a Quantitative Gait Analysis platform for the extraction of muscular implications features in ordinary motor action, such as gait. The here proposed platform is used for the quantification of PD symptoms. Addressing the wearable trend, the proposed architecture is able to define the real-time modulation of the muscular indexes by using 8 EMG wireless nodes positioned on lower limbs. The implemented system “translates” the acquisition in a 1-bit signal, exploiting a dynamic thresholding algorithm. The resulting 1-bit signals are used both to define muscular indexes both to drastically reduce the amount of data to be analyzed, preserving at the same time the muscular information. The overall architecture has been fully implemented on Altera Cyclone V FPGA. The system has been tested on 4 subjects: 2 affected by PD and 2 healthy subjects (control group). The experimental results highlight the validity of the proposed solution in Disease recognition and the outcomes match the clinical literature results

Ethical Analysis of Brain Augmentation Through Nanotechnology

The use of nanoparticles for drug delivery and neural cell manipulation may soon allow for organic and electronic brain augmentations. Medical technology being used for cognitive enhancement brings a host of ethical questions related to safety, justice, privacy, and individuality. Issues concerning medical consent and intellectual property will be skewed as neuroscience expands our understanding of the brain, growing our capacity to read and modify it. Socioeconomic strata may realign based on augmentations and employment opportunities may become dependent on specific cognitive enhancements. Long-term effects of unregulated nanoparticle usage could elicit an environmental or human health disaster. The potential for large scale societal change through nanotechnology and deviance from pharmaceutical paradigms is discussed through a utilitarian lens

Efficiency evaluation of external environments control using bio-signals

There are many types of bio-signals with various control application prospects. This dissertation regards possible application domain of electroencephalographic signal. The implementation of EEG signals, as a source of information used for control of external devices, became recently a growing concern in the scientific world. Application of electroencephalographic signals in Brain-Computer Interfaces (BCI) (variant of Human-Computer Interfaces (HCI)) as an implement, which enables direct and fast communication between the human brain and an external device, has become recently very popular. Currently available on the market, BCI solutions require complex signal processing methodology, which results in the need of an expensive equipment with high computing power. In this work, a study on using various types of EEG equipment in order to apply the most appropriate one was conducted. The analysis of EEG signals is very complex due to the presence of various internal and external artifacts. The signals are also sensitive to disturbances and non-stochastic, what makes the analysis a complicated task. The research was performed on customised (built by the author of this dissertation) equipment, on professional medical device and on Emotiv EPOC headset. This work concentrated on application of an inexpensive, easy to use, Emotiv EPOC headset as a tool for gaining EEG signals. The project also involved application of embedded system platform - TS-7260. That solution caused limits in choosing an appropriate signal processing method, as embedded platforms characterise with a little efficiency and low computing power. That aspect was the most challenging part of the whole work. Implementation of the embedded platform enables to extend the possible future application of the proposed BCI. It also gives more flexibility, as the platform is able to simulate various environments. The study did not involve the use of traditional statistical or complex signal processing methods. The novelty of the solution relied on implementation of the basic mathematical operations. The efficiency of this method was also presented in this dissertation. Another important aspect of the conducted study is that the research was carried out not only in a laboratory, but also in an environment reflecting real-life conditions. The results proved efficiency and suitability of the implementation of the proposed solution in real-life environments. The further study will focus on improvement of the signal-processing method and application of other bio-signals - in order to extend the possible applicability and ameliorate its effectiveness

A cybersecure P300-based brain-to-computer interface against noise-based and fake P300 cyberattacks

In a progressively interconnected world where the internet of things (IoT), ubiquitous computing, and artificial intelligence are leading to groundbreaking technology, cybersecurity remains an underdeveloped aspect. This is particularly alarming for brain-to-computer interfaces (BCIs), where hackers can threaten the user’s physical and psychological safety. In fact, standard algorithms currently employed in BCI systems are inadequate to deal with cyberattacks. In this paper, we propose a solution to improve the cybersecurity of BCI systems. As a case study, we focus on P300-based BCI systems using support vector machine (SVM) algorithms and EEG data. First, we verified that SVM algorithms are incapable of identifying hacking by simulating a set of cyberattacks using fake P300 signals and noise-based attacks. This was achieved by comparing the performance of several models when validated using real and hacked P300 datasets. Then, we implemented our solution to improve the cybersecurity of the system. The proposed solution is based on an EEG channel mixing approach to identify anomalies in the transmission channel due to hacking. Our study demonstrates that the proposed architecture can successfully identify 99.996% of simulated cyberattacks, implementing a dedicated counteraction that preserves most of BCI functions

A Human-Centric Metaverse Enabled by Brain-Computer Interface: A Survey

The growing interest in the Metaverse has generated momentum for members of academia and industry to innovate toward realizing the Metaverse world. The Metaverse is a unique, continuous, and shared virtual world where humans embody a digital form within an online platform. Through a digital avatar, Metaverse users should have a perceptual presence within the environment and can interact and control the virtual world around them. Thus, a human-centric design is a crucial element of the Metaverse. The human users are not only the central entity but also the source of multi-sensory data that can be used to enrich the Metaverse ecosystem. In this survey, we study the potential applications of Brain-Computer Interface (BCI) technologies that can enhance the experience of Metaverse users. By directly communicating with the human brain, the most complex organ in the human body, BCI technologies hold the potential for the most intuitive human-machine system operating at the speed of thought. BCI technologies can enable various innovative applications for the Metaverse through this neural pathway, such as user cognitive state monitoring, digital avatar control, virtual interactions, and imagined speech communications. This survey first outlines the fundamental background of the Metaverse and BCI technologies. We then discuss the current challenges of the Metaverse that can potentially be addressed by BCI, such as motion sickness when users experience virtual environments or the negative emotional states of users in immersive virtual applications. After that, we propose and discuss a new research direction called Human Digital Twin, in which digital twins can create an intelligent and interactable avatar from the user's brain signals. We also present the challenges and potential solutions in synchronizing and communicating between virtual and physical entities in the Metaverse

Sensing with Earables: A Systematic Literature Review and Taxonomy of Phenomena

Earables have emerged as a unique platform for ubiquitous computing by augmenting ear-worn devices with state-of-the-art sensing. This new platform has spurred a wealth of new research exploring what can be detected on a wearable, small form factor. As a sensing platform, the ears are less susceptible to motion artifacts and are located in close proximity to a number of important anatomical structures including the brain, blood vessels, and facial muscles which reveal a wealth of information. They can be easily reached by the hands and the ear canal itself is affected by mouth, face, and head movements. We have conducted a systematic literature review of 271 earable publications from the ACM and IEEE libraries. These were synthesized into an open-ended taxonomy of 47 different phenomena that can be sensed in, on, or around the ear. Through analysis, we identify 13 fundamental phenomena from which all other phenomena can be derived, and discuss the different sensors and sensing principles used to detect them. We comprehensively review the phenomena in four main areas of (i) physiological monitoring and health, (ii) movement and activity, (iii) interaction, and (iv) authentication and identification. This breadth highlights the potential that earables have to offer as a ubiquitous, general-purpose platform

Sensing with Earables: A Systematic Literature Review and Taxonomy of Phenomena

Earables have emerged as a unique platform for ubiquitous computing by augmenting ear-worn devices with state-of-the-art sensing. This new platform has spurred a wealth of new research exploring what can be detected on a wearable, small form factor. As a sensing platform, the ears are less susceptible to motion artifacts and are located in close proximity to a number of important anatomical structures including the brain, blood vessels, and facial muscles which reveal a wealth of information. They can be easily reached by the hands and the ear canal itself is affected by mouth, face, and head movements. We have conducted a systematic literature review of 271 earable publications from the ACM and IEEE libraries. These were synthesized into an open-ended taxonomy of 47 different phenomena that can be sensed in, on, or around the ear. Through analysis, we identify 13 fundamental phenomena from which all other phenomena can be derived, and discuss the different sensors and sensing principles used to detect them. We comprehensively review the phenomena in four main areas of (i) physiological monitoring and health, (ii) movement and activity, (iii) interaction, and (iv) authentication and identification. This breadth highlights the potential that earables have to offer as a ubiquitous, general-purpose platform

Motor imagery based EEG features visualization for BCI applications

Over recent years, electroencephalography's (EEG) use in the state-of-the-art brain-computer interface (BCI) technology has broadened to augment the quality of life, both with medical and non-medical applicationS. For medical applications, the availability of real-time data for processing, which could be used as command Signals to control robotic devices, is limited to specific platformS. This paper focuses on the possibility to analyse and visualize EEG signal features using OpenViBE acquisition platform in offline mode apart from its default real-time processing capability, and the options available for processing of data in offline mode. We employed OpenViBE platform to acquire EEG Signals, pre-process it and extract features for a BCI System. For testing purposes, we analysed and tried to visualize EEG data offline, by developing scenarios, using method for quantification of event-related (de)synchronization ERD/ERS patterns, as well as, built in signal processing algorithms available in OpenViBE-designer toolbox. Acquired data was based on deployment of standard Graz BCI experimental protocol, used for foot kinaesthetic motor imagery (KMI). Results clearly reflect that the platform OpenViBE is a streaming tool that encourages processing and analysis of EEG data online, contrary to analysis, or visualization of data in offline, or global mode. For offline analysis and visualization of data, other relevant platforms are discussed. In online execution of BCI, OpenViBE is a potential tool for the control of wearable lower-limb devices, robotic vehicles and rehabilitation equipment. Other applications include remote control of mechatronic devices, or driving of passenger cars by human thoughtS