Grid simulation services for the medical community

The first part of this paper presents a selection of medical simulation applications, including image reconstruction, near real-time registration for neuro-surgery, enhanced dose distribution calculation for radio-therapy, inhaled drug delivery prediction, plastic surgery planning and cardio-vascular system simulation. The latter two topics are discussed in some detail. In the second part, we show how such services can be made available to the clinical practitioner using Grid technology. We discuss the developments and experience made during the EU project GEMSS, which provides reliable, efficient, secure and lawful medical Grid services

End-to-End QoS Support for a Medical Grid Service Infrastructure

Quality of Service support is an important prerequisite for the adoption of Grid technologies for medical applications. The GEMSS Grid infrastructure addressed this issue by offering end-to-end QoS in the form of explicit timeliness guarantees for compute-intensive medical simulation services. Within GEMSS, parallel applications installed on clusters or other HPC hardware may be exposed as QoS-aware Grid services for which clients may dynamically negotiate QoS constraints with respect to response time and price using Service Level Agreements. The GEMSS infrastructure and middleware is based on standard Web services technology and relies on a reservation based approach to QoS coupled with application specific performance models. In this paper we present an overview of the GEMSS infrastructure, describe the available QoS and security mechanisms, and demonstrate the effectiveness of our methods with a Grid-enabled medical imaging service

An Analysis of Service Ontologies

Services are increasingly shaping the world’s economic activity. Service provision and consumption have been profiting from advances in ICT, but the decentralization and heterogeneity of the involved service entities still pose engineering challenges. One of these challenges is to achieve semantic interoperability among these autonomous entities. Semantic web technology aims at addressing this challenge on a large scale, and has matured over the last years. This is evident from the various efforts reported in the literature in which service knowledge is represented in terms of ontologies developed either in individual research projects or in standardization bodies. This paper aims at analyzing the most relevant service ontologies available today for their suitability to cope with the service semantic interoperability challenge. We take the vision of the Internet of Services (IoS) as our motivation to identify the requirements for service ontologies. We adopt a formal approach to ontology design and evaluation in our analysis. We start by defining informal competency questions derived from a motivating scenario, and we identify relevant concepts and properties in service ontologies that match the formal ontological representation of these questions. We analyze the service ontologies with our concepts and questions, so that each ontology is positioned and evaluated according to its utility. The gaps we identify as the result of our analysis provide an indication of open challenges and future work

Cloudbus Toolkit for Market-Oriented Cloud Computing

This keynote paper: (1) presents the 21st century vision of computing and identifies various IT paradigms promising to deliver computing as a utility; (2) defines the architecture for creating market-oriented Clouds and computing atmosphere by leveraging technologies such as virtual machines; (3) provides thoughts on market-based resource management strategies that encompass both customer-driven service management and computational risk management to sustain SLA-oriented resource allocation; (4) presents the work carried out as part of our new Cloud Computing initiative, called Cloudbus: (i) Aneka, a Platform as a Service software system containing SDK (Software Development Kit) for construction of Cloud applications and deployment on private or public Clouds, in addition to supporting market-oriented resource management; (ii) internetworking of Clouds for dynamic creation of federated computing environments for scaling of elastic applications; (iii) creation of 3rd party Cloud brokering services for building content delivery networks and e-Science applications and their deployment on capabilities of IaaS providers such as Amazon along with Grid mashups; (iv) CloudSim supporting modelling and simulation of Clouds for performance studies; (v) Energy Efficient Resource Allocation Mechanisms and Techniques for creation and management of Green Clouds; and (vi) pathways for future research.Comment: 21 pages, 6 figures, 2 tables, Conference pape

Proactive SLA negotiation for service based systems: Initial implementation and evaluation experience

This paper describes a framework that we have developed to integrate proactive SLA negotiation with dynamic service discovery to provide cohesive runtime support for both these activities. The proactive negotiation of SLAs as part of service discovery is necessary for reducing the extent of interruptions during the operation of a service based system when the need for replacing services in it arises. The developed framework discovers alternative candidate constituent services for a service client application, and negotiates/agrees but does not activate SLAs with these services until the need for using a service becomes necessary. A prototype tool has been implemented to realize the framework. This prototype is discussed in the paper along with the results of the initial evaluation of the framework

A Reliable and Cost-Efficient Auto-Scaling System for Web Applications Using Heterogeneous Spot Instances

Cloud providers sell their idle capacity on markets through an auction-like mechanism to increase their return on investment. The instances sold in this way are called spot instances. In spite that spot instances are usually 90% cheaper than on-demand instances, they can be terminated by provider when their bidding prices are lower than market prices. Thus, they are largely used to provision fault-tolerant applications only. In this paper, we explore how to utilize spot instances to provision web applications, which are usually considered availability-critical. The idea is to take advantage of differences in price among various types of spot instances to reach both high availability and significant cost saving. We first propose a fault-tolerant model for web applications provisioned by spot instances. Based on that, we devise novel auto-scaling polices for hourly billed cloud markets. We implemented the proposed model and policies both on a simulation testbed for repeatable validation and Amazon EC2. The experiments on the simulation testbed and the real platform against the benchmarks show that the proposed approach can greatly reduce resource cost and still achieve satisfactory Quality of Service (QoS) in terms of response time and availability