19,310 research outputs found

    Semantic-based policy engineering for autonomic systems

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    This paper presents some important directions in the use of ontology-based semantics in achieving the vision of Autonomic Communications. We examine the requirements of Autonomic Communication with a focus on the demanding needs of ubiquitous computing environments, with an emphasis on the requirements shared with Autonomic Computing. We observe that ontologies provide a strong mechanism for addressing the heterogeneity in user task requirements, managed resources, services and context. We then present two complimentary approaches that exploit ontology-based knowledge in support of autonomic communications: service-oriented models for policy engineering and dynamic semantic queries using content-based networks. The paper concludes with a discussion of the major research challenges such approaches raise

    Heterogeneous biomedical database integration using a hybrid strategy: a p53 cancer research database.

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    Complex problems in life science research give rise to multidisciplinary collaboration, and hence, to the need for heterogeneous database integration. The tumor suppressor p53 is mutated in close to 50% of human cancers, and a small drug-like molecule with the ability to restore native function to cancerous p53 mutants is a long-held medical goal of cancer treatment. The Cancer Research DataBase (CRDB) was designed in support of a project to find such small molecules. As a cancer informatics project, the CRDB involved small molecule data, computational docking results, functional assays, and protein structure data. As an example of the hybrid strategy for data integration, it combined the mediation and data warehousing approaches. This paper uses the CRDB to illustrate the hybrid strategy as a viable approach to heterogeneous data integration in biomedicine, and provides a design method for those considering similar systems. More efficient data sharing implies increased productivity, and, hopefully, improved chances of success in cancer research. (Code and database schemas are freely downloadable, http://www.igb.uci.edu/research/research.html.)

    Data integration through service-based mediation for web-enabled information systems

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    The Web and its underlying platform technologies have often been used to integrate existing software and information systems. Traditional techniques for data representation and transformations between documents are not sufficient to support a flexible and maintainable data integration solution that meets the requirements of modern complex Web-enabled software and information systems. The difficulty arises from the high degree of complexity of data structures, for example in business and technology applications, and from the constant change of data and its representation. In the Web context, where the Web platform is used to integrate different organisations or software systems, additionally the problem of heterogeneity arises. We introduce a specific data integration solution for Web applications such as Web-enabled information systems. Our contribution is an integration technology framework for Web-enabled information systems comprising, firstly, a data integration technique based on the declarative specification of transformation rules and the construction of connectors that handle the integration and, secondly, a mediator architecture based on information services and the constructed connectors to handle the integration process

    UK utility data integration: overcoming schematic heterogeneity

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    In this paper we discuss syntactic, semantic and schematic issues which inhibit the integration of utility data in the UK. We then focus on the techniques employed within the VISTA project to overcome schematic heterogeneity. A Global Schema based architecture is employed. Although automated approaches to Global Schema definition were attempted the heterogeneities of the sector were too great. A manual approach to Global Schema definition was employed. The techniques used to define and subsequently map source utility data models to this schema are discussed in detail. In order to ensure a coherent integrated model, sub and cross domain validation issues are then highlighted. Finally the proposed framework and data flow for schematic integration is introduced
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