Fertility Preservation after a Cancer Diagnosis: A Systematic Review of Adolescents', Parents', and Providers’ Perspectives, Experiences, and Preferences

Study Objective Survival into adulthood is now a reality for many adolescents facing cancer. Fertility preservation (FP) is rapidly advancing, but oncology providers and health systems struggle to incorporate the newest FP technologies into the clinical care of adolescents. Our objective was to systematically review and synthesize the available data regarding the perspectives, experiences, and preferences of adolescents, parents, and oncology providers about FP to inform clinical implementation of FP technologies. Design, Setting, Participants, Interventions, and Main Outcome Measures Five electronic databases (PubMed, Embase, Web of Knowledge, Cumulative Index to Nursing and Allied Health Literature, PsychInfo) were systematically searched for studies published between January 1999 and May 2014. Adolescents were defined as 12-18 years at the time of diagnosis or designated as pubertal/postpubertal and younger than 18 years of age. Studies were assessed for methodological quality, data were extracted using a standardized form, and results were synthesized using guidelines for a narrative syntheses of quantitative and qualitative data. Results In total, 1237 records were identified, with 22 articles, representing 17 unique studies that met the inclusion criteria. The following topics were consistently observed across studies and populations: (1) fertility in trust; (2) decision-making challenges; (3) provider knowledge and practices; and (4) discrepancies between desired and actual experiences. Conclusion Despite the challenges associated with a new cancer diagnosis, adolescents and parents value the opportunity to discuss fertility concerns and preservation options. Providers play an important role in addressing these topics for families and efforts should be made to incorporate FP discussions into routine cancer care for all adolescents, with attention paid to the unique needs of adolescents and their parents

Violence indicators in Quebrada de Humahuaca, Jujuy, Argentina: The Regional Development Period from a regional perspective

Quebrada de Humahuaca (Jujuy, Argentina) has been extensively studied by archaeologists. Studies have been focused mainly on the Late Regional Development Period (1250 1430 AD), which has been defined as a time of social conflict. In this paper we present bioarchaeological evidence of interper-sonal violence related trauma found in populations of the region. A sample of 153 skulls from three sites of Quebrada de Humahuaca: Los Amarillos, La Huerta and Yacoraite, were analyzed, differentiating antemortem and perimortem fractures, cut marks as well as the presence of trophy skulls. The results were subjected to nonparametric statistical tests, in order to assess inter-site level differences, sex and age distribution. Bioarchaeological analysis determined a high frequency of interpersonal violence related trauma. Most registered injuries belonged to the antemortem type, demonstrating that the individuals of those events that had generated said cranial trauma had managed to survive. Interpersonal violence affected both men and women the same, registering no differences in neither sex nor age group, however evidence of trauma varied geographically from site to site. Statistical calculations reveal that the Yacoraite site is where the highest frequency of trauma was found, while La Huerta is where the highest level of trophy skulls was registered.Fil: Seldes, Verónica. Universidad de Buenos Aires. Facultad de Filosofía y Letras. Departamento de Ciencias Antropológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Botta, Florencia Natalia. Universidad de Buenos Aires. Facultad de Filosofía y Letras; Argentin

Recent developments in scholarly communication: a review

This review article on recent developments in scholarly communication focuses on the content of three 2013 publications: The future of scholarly communication, edited by Deborah Shorley; Debating open access, edited by Nigel Vincent and Chris Wickham; The big deal and the damage done, by Walt Crawford