A Novel Needle-Type SV-GMR Sensor for Biomedical Applications

Cancer is the most deadly disease in the world today. There is a variety of different treatment methods for cancer, including radiotherapy and chemotherapy with anticancer drugs that have been in use over a long period of time. Hyperthermia is one of the cancer treatment methods that utilizes the property that cancer cells are more sensitive to temperature than normal cells. The control of temperature is an important task in achieving success using this treatment method. This paper reports the development of a novel needle-type nanosensor based on the spin-valve giant magnetoresistive (SV-GMR) technique to measure the magnetic flux density inside the body via pricking the needle. The sensor has been fabricated. The modeling and experimental results of flux density measurement have been reported. From the information of flux density, the temperature rise can be estimated to permit the delivery of controlled heating to precisely defined locations in controlled hyperthermia cancer treatment. The actual experiment with human is under investigation. © 2007, IEEE. All rights reserved.Proceedings of the 1997 2nd International Conference on Power Electronics and Drive Systems, PEDS. Part 2 (of 2); Singapore, Singapore; ; 26 May 1997 through 29 May 1997; Code 4701

Estimation of Low-Concentration Magnetic Fluid Density with GMR Sensor

This paper describes a new application of a spin-valve type giant magnetoresistance sensor in the biomedical field. The hyperthermia treatment, based on the hysteresis loss of magnetite under external ac fields, requires determination of the content density of magnetite injected inside the body to control the heat capacity. We propose a low-invasive methodology to estimate the density of magnetite by measuring magnetic fields inside the cavity. For this purpose, we investigated the relationship between the density of magnetite and the magnetic fields, and developed a needle-type magnetic probe with a giant magnetoresistance sensor for low-invasive measurement. The experimental results demonstrate the possibility of estimating the low-concentration density of magnetite injected into the body. © 2008 American Institute of Physics

Low-Invasive Detection of Magnetic Particles inside Human Body

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