2,155 research outputs found

    An automated pattern recognition system for classifying indirect immunofluorescence images for HEp-2 cells and specimens

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    AbstractImmunofluorescence antinuclear antibody tests are important for diagnosis and management of autoimmune conditions; a key step that would benefit from reliable automation is the recognition of subcellular patterns suggestive of different diseases. We present a system to recognize such patterns, at cellular and specimen levels, in images of HEp-2 cells. Ensembles of SVMs were trained to classify cells into six classes based on sparse encoding of texture features with cell pyramids, capturing spatial, multi-scale structure. A similar approach was used to classify specimens into seven classes. Software implementations were submitted to an international contest hosted by ICPR 2014 (Performance Evaluation of Indirect Immunofluorescence Image Analysis Systems). Mean class accuracies obtained on heldout test data sets were 87.1% and 88.5% for cell and specimen classification respectively. These were the highest achieved in the competition, suggesting that our methods are state-of-the-art. We provide detailed descriptions and extensive experiments with various features and encoding methods

    Optimized neural architecture for automatic landslide detection from high-resolution airborne laser scanning data

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    © 2017 by the authors. Licensee MDPI, Basel, Switzerland. An accurate inventory map is a prerequisite for the analysis of landslide susceptibility, hazard, and risk. Field survey, optical remote sensing, and synthetic aperture radar techniques are traditional techniques for landslide detection in tropical regions. However, such techniques are time consuming and costly. In addition, the dense vegetation of tropical forests complicates the generation of an accurate landslide inventory map for these regions. Given its ability to penetrate vegetation cover, high-resolution airborne light detection and ranging (LiDAR) has been used to generate accurate landslide maps. This study proposes the use of recurrent neural networks (RNN) and multi-layer perceptron neural networks (MLP-NN) in landscape detection. These efficient neural architectures require little or no prior knowledge compared with traditional classification methods. The proposed methods were tested in the Cameron Highlands, Malaysia. Segmentation parameters and feature selection were respectively optimized using a supervised approach and correlation-based feature selection. The hyper-parameters of network architecture were defined based on a systematic grid search. The accuracies of the RNN and MLP-NN models in the analysis area were 83.33% and 78.38%, respectively. The accuracies of the RNN and MLP-NN models in the test area were 81.11%, and 74.56%, respectively. These results indicated that the proposed models with optimized hyper-parameters produced the most accurate classification results. LiDAR-derived data, orthophotos, and textural features significantly affected the classification results. Therefore, the results indicated that the proposed methods have the potential to produce accurate and appropriate landslide inventory in tropical regions such as Malaysia

    A Comparative Study for 2D and 3D Computer-aided Diagnosis Methods for Solitary Pulmonary Nodules

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    Many computer-aided diagnosis (CAD) methods, including 2D and 3D approaches, have been proposed for solitary pulmonary nodules (SPNs). However, the detection and diagnosis of SPNs remain challenging in many clinical circumstances. One goal of this work is to investigate the relative diagnostic accuracy of 2D and 3D methods. An additional goal is to develop a two-stage approach that combines the simplicity of 2D and the accuracy of 3D methods. The experimental results show statistically significant differences between the diagnostic accuracy of 2D and 3D methods. The results also show that with a very minor drop in diagnostic performance the two-stage approach can significantly reduce the number of nodules needed to be processed by the 3D method, streamlining the computational demand
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