D6.3 Intermediate system evaluation results

The overall purpose of METIS is to develop a 5G system concept that fulfil s the requirements of the beyond-2020 connected information society and to extend today’s wireless communication systems for new usage cases. First, in this deliverable an updated view on the overall METIS 5G system concept is presented. Thereafter, simulation results for the most promising technology components supporting the METIS 5G system concept are reported. Finally, s imulation results are presented for one relevant aspect of each Horizontal Topic: Direct Device - to - Device Communication, Massive Machine Communication, Moving Networks, Ultra - Dense Networks, and Ultra - Reliable Communication.Popovski, P.; Mange, G.; Fertl, P.; Gozálvez - Serrano, D.; Droste, H.; Bayer, N.; Roos, A.... (2014). D6.3 Intermediate system evaluation results. http://hdl.handle.net/10251/7676

Learning-Assisted User Clustering in Cell-Free Massive MIMO-NOMA Networks

The superior spectral efficiency (SE) and user fairness feature of non-orthogonal multiple access (NOMA) systems are achieved by exploiting user clustering (UC) more efficiently. However, a random UC certainly results in a suboptimal solution while an exhaustive search method comes at the cost of high complexity, especially for systems of medium-to-large size. To address this problem, we develop two efficient unsupervised machine learning based UC algorithms, namely k-means++ and improved k-means++, to effectively cluster users into disjoint clusters in cell-free massive multiple-input multiple-output (CFmMIMO) system. Adopting full-pilot zero-forcing at access points (APs) to comprehensively assess the system performance, we formulate the sum SE optimization problem taking into account power constraints at APs, necessary conditions for implementing successive interference cancellation, and required SE constraints at user equipments. The formulated optimization problem is highly non-convex, and thus, it is difficult to obtain the global optimal solution. Therefore, we develop a simple yet efficient iterative algorithm for its solution. In addition, the performance of collocated massive MIMO-NOMA (COmMIMO-NOMA) system is also characterized. Numerical results are provided to show the superior performance of the proposed UC algorithms compared to baseline schemes. The effectiveness of applying NOMA in CFmMIMO and COmMIMO systems is also validated

Device-to-device communications for 5G Radio Access Networks

Nowadays it is very popular to share video clips and images to one’s social network in the proximity. Direct device-to-device (D2D) communication is one of the means to respond to this requirement. D2D offers users improved end-to-end latency times, and additionally can provide higher data rates. At the same time the overall cellular network congestion decreases. D2D is also known as Proximity Services (ProSe). LTE is missing direct D2D communication. Currently D2D for 5G is standardised in the 3rd Generation Partnership Project (3GPP) Releases 12, and in parallel Mobile and wireless communications Enablers for the Twenty-twenty Information Society (METIS) project has D2D as one of its research topics. Multiple articles have been published about D2D communication. This thesis is a literature based thesis following D2D communication in 5G literature. The scope is to describe similarities and differences found in Technical Reports and Technical Specifications of the 3GPP Release 12, in deliverables written in METIS project and in some selected D2D related publications about D2D communications. 3GPP Release 12 concentrates on ProSe at least for public safety. ProSe communication out-of-coverage is only for public safety purposes. METIS provides multiple solutions for diverse D2D topics, for example, device discovery, radio resource management, mobility management and relaying. METIS provides solutions for D2D communication not yet mature enough for development and implementation but which might be realized in the future.Nykyisin on suosittua lähettää lyhyitä videoita tai kuvia läheisyydessä oleville ystäville. Laitteiden välinen suora kommunikointi eli D2D-viestintä tuo ratkaisun tähän vaatimukseen. D2D-viestinnän ansiosta viive lyhenee ja lisäksi siirtonopeudet kasvavat. Samaan aikaan koko verkon kuormitus vähenee. Suora kahden laitteen välinen kommunikointi puuttuu LTE:stä. Tällä hetkellä 3GPP Release 12 standardisoi suoraa kahden laitteen välistä kommunikointia. Samanaikaisesti Mobile and wireless communications Enablers for the Twenty-twenty Information Society (METIS) –projektin yhtenä tutkimuskohteenaan on kahden laitteen välinen suora kommunikointi, Lisäksi on lukuisia julkaisuja liittyen D2D-viestintään. Tämä diplomityö perustuu kirjallisuuteen. Sen tavoitteena on selvittää, miten kahden laitteen välistä suoraa kommunikointia on kuvattu 3GPP Release 12:ta teknisissä spesifikaatioissa, METIS-projektin julkaisuissa sekä muutamassa valitussa tieteellisessä julkaisussa. Tavoitteena on selvittää D2D-viestinnän yhtäläisyyksiä sekä poikkeamia. 3PGG Release 12 standardointi keskittyy D2D-viestinnän käyttöön ainakin julkisessa pelastustyössä. D2D-viestinnän tulee ainakin julkisessa pelastustyössä toimia myös siellä missä matkapuhelinverkko ei toimi tai sitä ei ole olemassa. METIS tarjoaa useita ratkaisuja D2D-viestinnän eri osa-alueille, esimerkiksi laitteiden tunnistamiseen, resurssien hallintaan, liikkuvuuden hallintaa ja viestien edelleen lähettämiseen. METIS-projekti on tuottanut D2D-viestinnän ratkaisuja, joiden toteuttaminen on järkevää ja mahdollista vasta tulevaisuudessa

D3.2 First performance results for multi -node/multi -antenna transmission technologies

This deliverable describes the current results of the multi-node/multi-antenna technologies investigated within METIS and analyses the interactions within and outside Work Package 3. Furthermore, it identifies the most promising technologies based on the current state of obtained results. This document provides a brief overview of the results in its first part. The second part, namely the Appendix, further details the results, describes the simulation alignment efforts conducted in the Work Package and the interaction of the Test Cases. The results described here show that the investigations conducted in Work Package 3 are maturing resulting in valuable innovative solutions for future 5G systems.Fantini. R.; Santos, A.; De Carvalho, E.; Rajatheva, N.; Popovski, P.; Baracca, P.; Aziz, D.... (2014). D3.2 First performance results for multi -node/multi -antenna transmission technologies. http://hdl.handle.net/10251/7675

D 3. 3 Final performance results and consolidated view on the most promising multi -node/multi -antenna transmission technologies

This document provides the most recent updates on the technical contributions and research challenges focused in WP3. Each Technology Component (TeC) has been evaluated under possible uniform assessment framework of WP3 which is based on the simulation guidelines of WP6. The performance assessment is supported by the simulation results which are in their mature and stable state. An update on the Most Promising Technology Approaches (MPTAs) and their associated TeCs is the main focus of this document. Based on the input of all the TeCs in WP3, a consolidated view of WP3 on the role of multinode/multi-antenna transmission technologies in 5G systems has also been provided. This consolidated view is further supported in this document by the presentation of the impact of MPTAs on METIS scenarios and the addressed METIS goals.Aziz, D.; Baracca, P.; De Carvalho, E.; Fantini, R.; Rajatheva, N.; Popovski, P.; Sørensen, JH.... (2015). D 3. 3 Final performance results and consolidated view on the most promising multi -node/multi -antenna transmission technologies. http://hdl.handle.net/10251/7675

Recent Trends in Communication Networks

In recent years there has been many developments in communication technology. This has greatly enhanced the computing power of small handheld resource-constrained mobile devices. Different generations of communication technology have evolved. This had led to new research for communication of large volumes of data in different transmission media and the design of different communication protocols. Another direction of research concerns the secure and error-free communication between the sender and receiver despite the risk of the presence of an eavesdropper. For the communication requirement of a huge amount of multimedia streaming data, a lot of research has been carried out in the design of proper overlay networks. The book addresses new research techniques that have evolved to handle these challenges

In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation.

Regulatory T cells (Tregs) have been shown to be critical in the balance between autoimmunity and tolerance and have been implicated in several human autoimmune diseases. However, the small number of Tregs in peripheral blood limits their therapeutic potential. Therefore, we developed a protocol that would allow for the expansion of Tregs while retaining their suppressive activity. We isolated CD4+CD25 hi cells from human peripheral blood and expanded them in vitro in the presence of anti-CD3 and anti-CD28 magnetic Xcyte Dynabeads and high concentrations of exogenous Interleukin (IL)-2. Tregs were effectively expanded up to 200-fold while maintaining surface expression of CD25 and other markers of Tregs: CD62L, HLA-DR, CCR6, and FOXP3. The expanded Tregs suppressed proliferation and cytokine secretion of responder PBMCs in co-cultures stimulated with anti-CD3 or alloantigen. Treg expansion is a critical first step before consideration of Tregs as a therapeutic intervention in patients with autoimmune or graft-versus-host disease