20,564 research outputs found
Machine Learning Applications in Studying Mental Health Among Immigrants and Racial and Ethnic Minorities: A Systematic Review
Background: The use of machine learning (ML) in mental health (MH) research
is increasing, especially as new, more complex data types become available to
analyze. By systematically examining the published literature, this review aims
to uncover potential gaps in the current use of ML to study MH in vulnerable
populations of immigrants, refugees, migrants, and racial and ethnic
minorities.
Methods: In this systematic review, we queried Google Scholar for ML-related
terms, MH-related terms, and a population of a focus search term strung
together with Boolean operators. Backward reference searching was also
conducted. Included peer-reviewed studies reported using a method or
application of ML in an MH context and focused on the populations of interest.
We did not have date cutoffs. Publications were excluded if they were narrative
or did not exclusively focus on a minority population from the respective
country. Data including study context, the focus of mental healthcare, sample,
data type, type of ML algorithm used, and algorithm performance was extracted
from each.
Results: Our search strategies resulted in 67,410 listed articles from Google
Scholar. Ultimately, 12 were included. All the articles were published within
the last 6 years, and half of them studied populations within the US. Most
reviewed studies used supervised learning to explain or predict MH outcomes.
Some publications used up to 16 models to determine the best predictive power.
Almost half of the included publications did not discuss their cross-validation
method.
Conclusions: The included studies provide proof-of-concept for the potential
use of ML algorithms to address MH concerns in these special populations, few
as they may be. Our systematic review finds that the clinical application of
these models for classifying and predicting MH disorders is still under
development
Recommended from our members
Defamiliarizing assessment and feedback: exploring the potential of ‘moments of engagement’ to throw light on the marking of undergraduate assignments
Assessors’ perspectives on their evaluative practices remain relatively under-researched. Given evidence that higher education assessment and feedback continue to be problematic, this paper proposes a specific methodological innovation with potential to contribute both to research and practice in this area. It explores the potential of a micro-analysis of textual engagement, nested within an ethnographic approach, to defamiliarize the often taken-for-granted practice of marking. The study on which the paper is based used screen capture combined with audio-recorded, concurrent talk-around-text to throw light on the processes, strategies and perspectives of eight teachers within one university as they assessed undergraduates’ work. This close-up focus was nested within broader ethnographic data generation incorporating interviews, marked assignments and other assessment-related texts. The paper presents selected ‘moments of engagement’ to show how this methodology can offer a renewed understanding of evaluative literacies as complex, ‘messy’ and shot through with influences invisible in the final assessed text but which may nevertheless be highly consequential. The paper concludes by reflecting on the potential for this type of data and analysis to contribute to assessor development and inform debate about the future of higher education assessment
Quantifying and Explaining Machine Learning Uncertainty in Predictive Process Monitoring: An Operations Research Perspective
This paper introduces a comprehensive, multi-stage machine learning
methodology that effectively integrates information systems and artificial
intelligence to enhance decision-making processes within the domain of
operations research. The proposed framework adeptly addresses common
limitations of existing solutions, such as the neglect of data-driven
estimation for vital production parameters, exclusive generation of point
forecasts without considering model uncertainty, and lacking explanations
regarding the sources of such uncertainty. Our approach employs Quantile
Regression Forests for generating interval predictions, alongside both local
and global variants of SHapley Additive Explanations for the examined
predictive process monitoring problem. The practical applicability of the
proposed methodology is substantiated through a real-world production planning
case study, emphasizing the potential of prescriptive analytics in refining
decision-making procedures. This paper accentuates the imperative of addressing
these challenges to fully harness the extensive and rich data resources
accessible for well-informed decision-making
Grasping nothing: a study of minimal ontologies and the sense of music
If music were to have a proper sense – one in which it is truly given – one might reasonably place this in sound and aurality. I contend, however, that no such sense exists; rather, the sense of music takes place, and it does so with the impossible. To this end, this thesis – which is a work of philosophy and music – advances an ontology of the impossible (i.e., it thinks the being of what, properly speaking, can have no being) and considers its implications for music, articulating how ontological aporias – of the event, of thinking the absolute, and of sovereignty’s dismemberment – imply senses of music that are anterior to sound. John Cage’s Silent Prayer, a nonwork he never composed, compels a rerethinking of silence on the basis of its contradictory status of existence; Florian Hecker et al.’s Speculative Solution offers a basis for thinking absolute music anew to the precise extent that it is a discourse of meaninglessness; and Manfred Werder’s [yearn] pieces exhibit exemplarily that music’s sense depends on the possibility of its counterfeiting. Inso-much as these accounts produce musical senses that take the place of sound, they are also understood to be performances of these pieces. Here, then, thought is music’s organon and its instrument
Single-cell RNA datasets and bulk RNA datasets analysis demonstrated C1Q+ tumor-associated macrophage as a major and antitumor immune cell population in osteosarcoma
BackgroundOsteosarcoma is the most frequent primary bone tumor with a poor prognosis. Immune infiltration proved to have a strong impact on prognosis. We analyzed single-cell datasets and bulk datasets to confirm the main immune cell populations and their properties in osteosarcoma.MethodsThe examples in bulk datasets GSE21257 and GSE32981 from the Gene Expression Omnibus database were divided into two immune infiltration level groups, and 34 differentially expressed genes were spotted. Then, we located these genes among nine major cell clusters and their subclusters identified from 99,668 individual cells in single-cell dataset GSE152048 including 11 osteosarcoma patients. Especially, the markers of all kinds of myeloid cells identified in single-cell dataset GSE152048 were set to gene ontology enrichment. We clustered the osteosarcoma samples in the TARGET-OS from the Therapeutically Applicable Research to Generate Effective Treatments dataset into two groups by complete component 1q positive macrophage markers and compared their survival.ResultsCompared with the low-immune infiltrated group, the high-immune infiltrated group showed a better prognosis. Almost all the 34 differentially expressed genes expressed higher or exclusively among myeloid cells. A group of complete component 1q-positive macrophages was identified from the myeloid cells. In the bulk dataset TARGET-OS, these markers and the infiltration of complete component 1q-positive macrophages related to longer survival.ConclusionsComplete component 1q-positive tumor-associated macrophages were the major immune cell population in osteosarcoma, which contributed to a better prognosis
A scoping review of natural language processing of radiology reports in breast cancer
Various natural language processing (NLP) algorithms have been applied in the literature to analyze radiology reports pertaining to the diagnosis and subsequent care of cancer patients. Applications of this technology include cohort selection for clinical trials, population of large-scale data registries, and quality improvement in radiology workflows including mammography screening. This scoping review is the first to examine such applications in the specific context of breast cancer. Out of 210 identified articles initially, 44 met our inclusion criteria for this review. Extracted data elements included both clinical and technical details of studies that developed or evaluated NLP algorithms applied to free-text radiology reports of breast cancer. Our review illustrates an emphasis on applications in diagnostic and screening processes over treatment or therapeutic applications and describes growth in deep learning and transfer learning approaches in recent years, although rule-based approaches continue to be useful. Furthermore, we observe increased efforts in code and software sharing but not with data sharing
Evaluating GPT-4 and ChatGPT on Japanese Medical Licensing Examinations
As large language models (LLMs) gain popularity among speakers of diverse
languages, we believe that it is crucial to benchmark them to better understand
model behaviors, failures, and limitations in languages beyond English. In this
work, we evaluate LLM APIs (ChatGPT, GPT-3, and GPT-4) on the Japanese national
medical licensing examinations from the past five years, including the current
year. Our team comprises native Japanese-speaking NLP researchers and a
practicing cardiologist based in Japan. Our experiments show that GPT-4
outperforms ChatGPT and GPT-3 and passes all six years of the exams,
highlighting LLMs' potential in a language that is typologically distant from
English. However, our evaluation also exposes critical limitations of the
current LLM APIs. First, LLMs sometimes select prohibited choices that should
be strictly avoided in medical practice in Japan, such as suggesting
euthanasia. Further, our analysis shows that the API costs are generally higher
and the maximum context size is smaller for Japanese because of the way
non-Latin scripts are currently tokenized in the pipeline. We release our
benchmark as Igaku QA as well as all model outputs and exam metadata. We hope
that our results and benchmark will spur progress on more diverse applications
of LLMs. Our benchmark is available at https://github.com/jungokasai/IgakuQA.Comment: Added results from the March 2023 exa
Neuroanatomical and gene expression features of the rabbit accessory olfactory system. Implications of pheromone communication in reproductive behaviour and animal physiology
Mainly driven by the vomeronasal system (VNS), pheromone
communication is involved in many species-specific fundamental innate socio-sexual behaviors such as mating and
fighting, which are essential for animal reproduction and survival. Rabbits are a unique model for studying
chemocommunication due to the discovery of the rabbit mammary pheromone, but paradoxically there has been a
lack of knowledge regarding its VNS pathway. In this work, we aim at filling this gap by approaching the system
from an integrative point of view, providing extensive anatomical and genomic data of the rabbit VNS, as well as
pheromone-mediated reproductive and behavioural studies. Our results build strong foundation for further
translational studies which aim at implementing the use of pheromones to improve animal production and welfare
Information Extraction from Documents: Question Answering vs Token Classification in real-world setups
Research in Document Intelligence and especially in Document Key Information
Extraction (DocKIE) has been mainly solved as Token Classification problem.
Recent breakthroughs in both natural language processing (NLP) and computer
vision helped building document-focused pre-training methods, leveraging a
multimodal understanding of the document text, layout and image modalities.
However, these breakthroughs also led to the emergence of a new DocKIE subtask
of extractive document Question Answering (DocQA), as part of the Machine
Reading Comprehension (MRC) research field. In this work, we compare the
Question Answering approach with the classical token classification approach
for document key information extraction. We designed experiments to benchmark
five different experimental setups : raw performances, robustness to noisy
environment, capacity to extract long entities, fine-tuning speed on Few-Shot
Learning and finally Zero-Shot Learning. Our research showed that when dealing
with clean and relatively short entities, it is still best to use token
classification-based approach, while the QA approach could be a good
alternative for noisy environment or long entities use-cases
Segment Anything in Medical Images
Segment anything model (SAM) has revolutionized natural image segmentation,
but its performance on medical images is limited. This work presents MedSAM,
the first attempt at extending the success of SAM to medical images, with the
goal of creating a universal tool for the segmentation of various medical
targets. Specifically, we first curate a large-scale medical image dataset,
encompassing over 200,000 masks across 11 different modalities. Then, we
develop a simple fine-tuning method to adapt SAM to general medical image
segmentation. Comprehensive experiments on 21 3D segmentation tasks and 9 2D
segmentation tasks demonstrate that MedSAM outperforms the default SAM model
with an average Dice Similarity Coefficient (DSC) of 22.5% and 17.6% on 3D and
2D segmentation tasks, respectively. The code and trained model are publicly
available at \url{https://github.com/bowang-lab/MedSAM}
- …