18 research outputs found

    Stochastic Switching Dynamics

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    Quantitative Models in Life Science Business

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    This open access book explores the field of life science business from a multidisciplinary perspective. Applying statistical, mathematical, game-theoretic, and data science tools to pharmaceutical and biotechnology business endeavors, the book describes value creation, value maintenance, and value realization in the life sciences as a sequence of processes using the quantitative language of applied mathematics. Written by experts from a variety of fields, the contributions illustrate the shift from a deterministic to a stochastic view of the processes involved, offering a new perspective on life sciences economics. The book covers topics such as valuing and managing intellectual property in life science, licensing in the pharmaceutical business, outsourcing pharmaceutical R&D, and stochastic modelling of a pharmaceutical supply chain. The book will appeal to scholars of economics and the life sciences, as well as to professionals in chemical and pharmaceutical industries

    Quantitative Models in Life Science Business

    Get PDF
    This open access book explores the field of life science business from a multidisciplinary perspective. Applying statistical, mathematical, game-theoretic, and data science tools to pharmaceutical and biotechnology business endeavors, the book describes value creation, value maintenance, and value realization in the life sciences as a sequence of processes using the quantitative language of applied mathematics. Written by experts from a variety of fields, the contributions illustrate the shift from a deterministic to a stochastic view of the processes involved, offering a new perspective on life sciences economics. The book covers topics such as valuing and managing intellectual property in life science, licensing in the pharmaceutical business, outsourcing pharmaceutical R&D, and stochastic modelling of a pharmaceutical supply chain. The book will appeal to scholars of economics and the life sciences, as well as to professionals in chemical and pharmaceutical industries

    Annual Research Report 2021

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    Generalized averaged Gaussian quadrature and applications

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    A simple numerical method for constructing the optimal generalized averaged Gaussian quadrature formulas will be presented. These formulas exist in many cases in which real positive GaussKronrod formulas do not exist, and can be used as an adequate alternative in order to estimate the error of a Gaussian rule. We also investigate the conditions under which the optimal averaged Gaussian quadrature formulas and their truncated variants are internal

    MS FT-2-2 7 Orthogonal polynomials and quadrature: Theory, computation, and applications

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    Quadrature rules find many applications in science and engineering. Their analysis is a classical area of applied mathematics and continues to attract considerable attention. This seminar brings together speakers with expertise in a large variety of quadrature rules. It is the aim of the seminar to provide an overview of recent developments in the analysis of quadrature rules. The computation of error estimates and novel applications also are described

    Non-Linear diffusion processes and applications

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    Diffusion models are useful tools for quantifying the dynamics of continuously evolving processes. Using diffusion models it is possible to formulate compact descriptions for the dynamics of real-world processes in terms of stochastic differential equations. Despite the exibility of these models, they can often be extremely difficult to work with. This is especially true for non-linear and/or time-inhomogeneous diffusion models where even basic statistical properties of the process can be elusive. As such, we explore various techniques for analysing non-linear diffusion models in contexts ranging from conducting inference under discrete observation and solving first passage time problems, to the analysis of jump diffusion processes and highly non-linear diffusion processes. We apply the methodology to a number of real-world ecological and financial problems of interest and demonstrate how non-linear diffusion models can be used to better understand such phenomena. In conjunction with the methodology, we develop a series of software packages that can be used to accurately and efficiently analyse various classes of non-linear diffusion models

    International Conference on Mathematical Analysis and Applications in Science and Engineering – Book of Extended Abstracts

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    The present volume on Mathematical Analysis and Applications in Science and Engineering - Book of Extended Abstracts of the ICMASC’2022 collects the extended abstracts of the talks presented at the International Conference on Mathematical Analysis and Applications in Science and Engineering – ICMA2SC'22 that took place at the beautiful city of Porto, Portugal, in June 27th-June 29th 2022 (3 days). Its aim was to bring together researchers in every discipline of applied mathematics, science, engineering, industry, and technology, to discuss the development of new mathematical models, theories, and applications that contribute to the advancement of scientific knowledge and practice. Authors proposed research in topics including partial and ordinary differential equations, integer and fractional order equations, linear algebra, numerical analysis, operations research, discrete mathematics, optimization, control, probability, computational mathematics, amongst others. The conference was designed to maximize the involvement of all participants and will present the state-of- the-art research and the latest achievements.info:eu-repo/semantics/publishedVersio
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