5,975 research outputs found
Segmentation of the left ventricle of the heart in 3-D+t MRI data using an optimized nonrigid temporal model
Modern medical imaging modalities provide large amounts of information in both the spatial and temporal domains and the incorporation of this information in a coherent algorithmic framework is a significant challenge. In this paper, we present a novel and intuitive approach to combine 3-D spatial and temporal (3-D + time) magnetic resonance imaging (MRI) data in an integrated segmentation algorithm to extract the myocardium of the left ventricle. A novel level-set segmentation process is developed that simultaneously delineates and tracks the boundaries of the left ventricle muscle. By encoding prior knowledge about cardiac temporal evolution in a parametric framework, an expectation-maximization algorithm optimally tracks the myocardial deformation over the cardiac cycle. The expectation step deforms the level-set function while the maximization step updates the prior temporal model parameters to perform the segmentation in a nonrigid sense
Spatio-Temporal Modelling of Perfusion Cardiovascular MRI
Myocardial perfusion MRI provides valuable insight into how coronary artery and microvascular diseases affect myocardial tissue. Stenosis in a coronary vessel leads to reduced maximum blood flow (MBF), but collaterals may secure the blood supply of the myocardium but with altered tracer kinetics. To date, quantitative analysis of myocardial perfusion MRI has only been performed on a local level, largely ignoring the contextual information inherent in different myocardial segments. This paper proposes to quantify the spatial dependencies between the local kinetics via a Hierarchical Bayesian Model (HBM). In the proposed framework, all local systems are modelled simultaneously along with their dependencies, thus allowing more robust context-driven estimation of local kinetics. Detailed validation on both simulated and patient data is provided
The identification of cellular automata
Although cellular automata have been widely studied as a class of the spatio temporal systems, very few investigators have studied how to identify the CA rules given observations of the patterns. A solution using a polynomial realization to describe the CA rule is reviewed in the present study based on the application of an orthogonal least squares algorithm. Three new neighbourhood detection methods are then reviewed as important preliminary analysis procedures to reduce the complexity of the estimation. The identification of excitable media is discussed using simulation examples and real data sets and a new method for the identification of
hybrid CA is introduced
Feature detection from echocardiography images using local phase information
Ultrasound images are characterized by their special speckle appearance, low contrast, and low signal-to-noise ratio. It is always challenging to extract important clinical information from these images. An important step before formal analysis is to transform the image to significant features of interest. Intensity based methods do not perform particularly well on ultrasound images. However, it has been previously shown that these images respond well to local phase-based methods which are theoretically intensity-invariant and thus suitable for ultrasound images. We extend the previous local phase-based method to detect features using the local phase computed from monogenic signal which is an isotropic extension of the analytic signal. We apply our method of multiscale feature-asymmetry measurement and local phase-gradient computation to cardiac ultrasound (echocardiography) images for the detection of endocardial, epicardial and myocardial centerline
Scalable Dense Non-rigid Structure-from-Motion: A Grassmannian Perspective
This paper addresses the task of dense non-rigid structure-from-motion
(NRSfM) using multiple images. State-of-the-art methods to this problem are
often hurdled by scalability, expensive computations, and noisy measurements.
Further, recent methods to NRSfM usually either assume a small number of sparse
feature points or ignore local non-linearities of shape deformations, and thus
cannot reliably model complex non-rigid deformations. To address these issues,
in this paper, we propose a new approach for dense NRSfM by modeling the
problem on a Grassmann manifold. Specifically, we assume the complex non-rigid
deformations lie on a union of local linear subspaces both spatially and
temporally. This naturally allows for a compact representation of the complex
non-rigid deformation over frames. We provide experimental results on several
synthetic and real benchmark datasets. The procured results clearly demonstrate
that our method, apart from being scalable and more accurate than
state-of-the-art methods, is also more robust to noise and generalizes to
highly non-linear deformations.Comment: 10 pages, 7 figure, 4 tables. Accepted for publication in Conference
on Computer Vision and Pattern Recognition (CVPR), 2018, typos fixed and
acknowledgement adde
Deep Learning using K-space Based Data Augmentation for Automated Cardiac MR Motion Artefact Detection
Quality assessment of medical images is essential for complete automation of
image processing pipelines. For large population studies such as the UK
Biobank, artefacts such as those caused by heart motion are problematic and
manual identification is tedious and time-consuming. Therefore, there is an
urgent need for automatic image quality assessment techniques. In this paper,
we propose a method to automatically detect the presence of motion-related
artefacts in cardiac magnetic resonance (CMR) images. As this is a highly
imbalanced classification problem (due to the high number of good quality
images compared to the low number of images with motion artefacts), we propose
a novel k-space based training data augmentation approach in order to address
this problem. Our method is based on 3D spatio-temporal Convolutional Neural
Networks, and is able to detect 2D+time short axis images with motion artefacts
in less than 1ms. We test our algorithm on a subset of the UK Biobank dataset
consisting of 3465 CMR images and achieve not only high accuracy in detection
of motion artefacts, but also high precision and recall. We compare our
approach to a range of state-of-the-art quality assessment methods.Comment: Accepted for MICCAI2018 Conferenc
Deep learning cardiac motion analysis for human survival prediction
Motion analysis is used in computer vision to understand the behaviour of
moving objects in sequences of images. Optimising the interpretation of dynamic
biological systems requires accurate and precise motion tracking as well as
efficient representations of high-dimensional motion trajectories so that these
can be used for prediction tasks. Here we use image sequences of the heart,
acquired using cardiac magnetic resonance imaging, to create time-resolved
three-dimensional segmentations using a fully convolutional network trained on
anatomical shape priors. This dense motion model formed the input to a
supervised denoising autoencoder (4Dsurvival), which is a hybrid network
consisting of an autoencoder that learns a task-specific latent code
representation trained on observed outcome data, yielding a latent
representation optimised for survival prediction. To handle right-censored
survival outcomes, our network used a Cox partial likelihood loss function. In
a study of 302 patients the predictive accuracy (quantified by Harrell's
C-index) was significantly higher (p < .0001) for our model C=0.73 (95 CI:
0.68 - 0.78) than the human benchmark of C=0.59 (95 CI: 0.53 - 0.65). This
work demonstrates how a complex computer vision task using high-dimensional
medical image data can efficiently predict human survival
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