Driving Postsecondary Success with Impact Investing: Executive Briefing Investment Opportunities in the Postsecondary Access and Success Ecosystem, Executive Summary

This research by Avivar Capital, funded by The Kresge Foundation and Lumina Foundation, identifies capital barriers and maps opportunities to deploy various forms of capital – including mission-related and program-related investments – to support America's need for talent while addressing challenges such as the increasing cost of education, the changing demographics of students and the rise of enabling technologies

The Price of Progress: Funding and Financing Alzheimer\u27s Disease Drug Development

Introduction Advancing research and treatment for Alzheimer\u27s disease (AD) and the search for effective treatments depend on a complex financial ecosystem involving federal, state, industry, advocacy, venture capital, and philanthropy funding approaches. Methods We conducted an expert review of the literature pertaining to funding and financing of translational research and drug development for AD. Results The federal government is the largest public funder of research in AD. The National Institute on Aging, National Institute of Mental Health, National Institute of General Medical Sciences, and National Center for Advancing Translational Science all fund aspects of research in AD drug development. Non-National Institutes of Health federal funding comes from the National Science Foundation, Veterans Administration, Food and Drug Administration, and the Center for Medicare and Medicaid Services. Academic Medical Centers host much of the federally funded basic science research and are increasingly involved in drug development. Funding of the “Valley of Death” involves philanthropy and federal funding through small business programs and private equity from seed capital, angel investors, and venture capital companies. Advocacy groups fund both basic science and clinical trials. The Alzheimer Association is the advocacy organization with the largest research support portfolio relevant to AD drug development. Pharmaceutical companies are the largest supporters of biomedical research worldwide; companies are most interested in late stage de-risked drugs. Drugs progressing into phase II and III are candidates for pharmaceutical industry support through licensing, mergers and acquisitions, and co-development collaborations. Discussion Together, the funding and financing entities involved in supporting AD drug development comprise a complex, interactive, dynamic financial ecosystem. Funding source interaction is largely unstructured and available funding is insufficient to meet all demands for new therapies. Novel approaches to funding such as mega-funds have been proposed and more integration of component parts would assist in accelerating drug development

Steering Capital: Optimizing Financial Support for Innovation in Public Education

Examines efforts to align capital to education innovation and calls for clarity and agreement on problems, goals, and metrics; an effective R&D system; an evidence-based culture of continuous improvement; and transparent, comparable, and useful data

Return on Equality: Investment Opportunities that Help Close the Global Gender Gap

There is significant opportunity for individual investors, asset managers and companies to move closer to achieving the goal of gender equality and make direct social, market and global economic impacts, according to a compelling report launched today by BNY Mellon and the UN Foundation.The report, Return on Equality: Investment Opportunities to Help Close the Global Gender Gap, reveals new insights that underscore the urgency and opportunities for closing the global gender gap and proposes steps investors can take to advance progress towards the United Nations' Sustianable Development Goal 5: Achieve gender equality and empower all women and girls." "We not only have a moral imperative to bridge the global gender gap, but the potential market benefits and investment opportunities in doing so are pivotal," according to Michael Cole-Fontayn, Executive Vice President, and Chairman of Europe, Middle East and Africa (EMEA). "Companies engaging in 'gender-lens' investing have typically supported women-led businesses and those promoting gender diversity. However, there is an increasing need to focus on the third (and less common) type of investing, in companies that advance gender equality through their products and services."Investors can now pursue these three gender-lens investment strategies through a variety of investment vehicles, including index funds and exchange traded funds (ETFs), venture capital and private equity opportunities, and innovative financing structures, such as private debt vehicles. However, investment vehicles related to products and services that advance gender equality are far and few in between.The five sectors examined in this report that present investment opportunities in products and services and further the advancement of women have an estimated market impact nearing U.S. $300 billion alone in incremental annual opportunity globally by 2025. They include telecommunications, contraception, childcare, water and energy

Advancing adult learning in Eastern Europe and Central Asia

This report presents available evidence on adult education and training in Europe and Central Asia (ECA), differentiating two separate types: continuing vocational education and training (CVET) for the employed, sought either by employers or individuals, and retraining and second chance education for the non?employed. This paper presents available evidence on the extent and patterns of lifelong learning in ECA. It argues that advancing adult education and training in ECA is important not only to meet the new skills demands but also to respond to a rapidly worsening demographic outlook across most of the region. While it is not equally important for all ECA countries, adult education and training should be high on the agenda of those ECA economies that are closest to the technological frontier and facing a demographic decline, such as the new European Union (EU) member States and Russia. The paper lays out a framework for government action to advance adult learning in ECA through a mix consisting of policy coordination between government and the enterprise sector, a sound regulatory regime and appropriate financial incentives.Access&Equity in Basic Education,Education For All,Primary Education,Teaching and Learning,Gender and Education

Automation of the longwall mining system

Cost effective, safe, and technologically sound applications of automation technology to underground coal mining were identified. The longwall analysis commenced with a general search for government and industry experience of mining automation technology. A brief industry survey was conducted to identify longwall operational, safety, and design problems. The prime automation candidates resulting from the industry experience and survey were: (1) the shearer operation, (2) shield and conveyor pan line advance, (3) a management information system to allow improved mine logistics support, and (4) component fault isolation and diagnostics to reduce untimely maintenance delays. A system network analysis indicated that a 40% improvement in productivity was feasible if system delays associated with all of the above four areas were removed. A technology assessment and conceptual system design of each of the four automation candidate areas showed that state of the art digital computer, servomechanism, and actuator technologies could be applied to automate the longwall system

New Lessons: The Power of Educating Adolescent Girls

Offers data and analysis on the impact of education on adolescent girls' lives and highlights promising approaches. Calls for evaluating girl-friendly education programs, compiling data on non-formal schools, and improving curricula, access, and supports

The New Role of Academia in Drug Development

Recommends ways for government, nonprofits, and academic institutions to work with the private sector to develop drugs and bring them to market more efficiently, including establishing models for intellectual property and technology transfer processes

Maximizing Impact: An Integrated Strategy for Grantmaking and Mission Investing in Climate Change

With funding from The Surdna Foundation, FSG has developed this report to help foundations identify how various mission investing instruments and opportunities can help them create greater impact. Guided by an expert Advisory Board and based on interviews with more than 50 practitioners from the field, the report provides a framework for foundations to think about how mission investments can create the greatest impact when combined with grants in an integrated program portfolio, with a specific focus on climate change

Private Sector Investment and Sustainable Development: The Current and Potential Role of Institutional Investors, Companies, Banks and Foundations in Sustainable Development

This paper seeks to provide the Financing for Development process with a perspective on the role institutional investors, companies, and foundations can play in the design and implementation of a financing strategy for global sustainability. This will help bridge the terminology and investment approaches of institutional investors, companies, foundations, and governments. The paper highlights ongoing efforts among private investors to increase the impact of their investments. It concludes with a set of key actions facing investors, companies and foundations in their transition towards investment practices that contribute to sustainable development