4,765 research outputs found

    A control algorithm for autonomous optimization of extracellular recordings

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    This paper develops a control algorithm that can autonomously position an electrode so as to find and then maintain an optimal extracellular recording position. The algorithm was developed and tested in a two-neuron computational model representative of the cells found in cerebral cortex. The algorithm is based on a stochastic optimization of a suitably defined signal quality metric and is shown capable of finding the optimal recording position along representative sampling directions, as well as maintaining the optimal signal quality in the face of modeled tissue movements. The application of the algorithm to acute neurophysiological recording experiments and its potential implications to chronic recording electrode arrays are discussed

    Neural Mixture Models with Expectation-Maximization for End-to-end Deep Clustering

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    Any clustering algorithm must synchronously learn to model the clusters and allocate data to those clusters in the absence of labels. Mixture model-based methods model clusters with pre-defined statistical distributions and allocate data to those clusters based on the cluster likelihoods. They iteratively refine those distribution parameters and member assignments following the Expectation-Maximization (EM) algorithm. However, the cluster representability of such hand-designed distributions that employ a limited amount of parameters is not adequate for most real-world clustering tasks. In this paper, we realize mixture model-based clustering with a neural network where the final layer neurons, with the aid of an additional transformation, approximate cluster distribution outputs. The network parameters pose as the parameters of those distributions. The result is an elegant, much-generalized representation of clusters than a restricted mixture of hand-designed distributions. We train the network end-to-end via batch-wise EM iterations where the forward pass acts as the E-step and the backward pass acts as the M-step. In image clustering, the mixture-based EM objective can be used as the clustering objective along with existing representation learning methods. In particular, we show that when mixture-EM optimization is fused with consistency optimization, it improves the sole consistency optimization performance in clustering. Our trained networks outperform single-stage deep clustering methods that still depend on k-means, with unsupervised classification accuracy of 63.8% in STL10, 58% in CIFAR10, 25.9% in CIFAR100, and 98.9% in MNIST

    A control algorithm for autonomous optimization of extracellular recordings

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