Recent Advances in Graph Partitioning

We survey recent trends in practical algorithms for balanced graph partitioning together with applications and future research directions

On the role of metaheuristic optimization in bioinformatics

Metaheuristic algorithms are employed to solve complex and large-scale optimization problems in many different fields, from transportation and smart cities to finance. This paper discusses how metaheuristic algorithms are being applied to solve different optimization problems in the area of bioinformatics. While the text provides references to many optimization problems in the area, it focuses on those that have attracted more interest from the optimization community. Among the problems analyzed, the paper discusses in more detail the molecular docking problem, the protein structure prediction, phylogenetic inference, and different string problems. In addition, references to other relevant optimization problems are also given, including those related to medical imaging or gene selection for classification. From the previous analysis, the paper generates insights on research opportunities for the Operations Research and Computer Science communities in the field of bioinformatics

An investigation of multilevel refinement in routing and location problems

Multilevel refinement is a collaborative hierarchical solution technique. The multilevel technique aims to enhance the solution process of optimisation problems by improving the asymptotic convergence in the quality of solutions produced by its underlying local search heuristics and/or improving the convergence rate of these heuristics. To these aims, the central methodologies of the multilevel technique are filtering solutions from the search space (via coarsening), reducing the amount of problem detail considered at each level of the solution process and providing a mechanism to the underlying local search heuristics for efficiently making large moves around the search space. The neighbourhoods accessible by these moves are typically inaccessible if the local search heuristics are applied to the un-coarsened problems. The methodologies combine to meet the multilevel technique's aims, because, as the multilevel technique iteratively coarsens, extends and refines a given problem, it reduces the possibility of the local search heuristic becoming trapped in local optima of poor quality. The research presented in this thesis investigates the application of multilevel refinement to classes of location and routing problems and develops numerous multilevel algorithms. Some of these algorithms are collaborative techniques for metaheuristics and others are collaborative techniques for local search heuristics. Additionally, new methods of coarsening for location and routing problems and enhancements for the multilevel technique are developed. It is demonstrated that the multilevel technique is suited to a wide array of problems. By extending the investigations of the multilevel technique across routing and location problems, the research was able to present generalisations regarding the multilevel technique's suitability, for these and similar types of problems. Finally, results on a number of well known benchmarking suites for location and routing problem are presented, comparing equivalent single-level and multilevel algorithms. These results demonstrate that the multilevel technique provides significant gains over its single-level counterparts. In all cases, the multilevel algorithm was able to improve the asymptotic convergence in the quality of solutions produced by the standard (single-level) local search heuristics or metaheuristics. The multilevel technique did not improve the convergence rate of the single-level's local search heuristics in all cases. However, for large-scale problems the multilevel variants scaled in a manner superior to the single-level techniques. The research also demonstrated that for sufficiently large problems, the multilevel technique was able to improve the asymptotic convergence in the quality of solutions at a sufficiently fast rate, such that the multilevel algorithms were able to produce superior results compared to the single-level versions, without refining the solution down to the most detailed level