Astigmatism and Pseudoaccommodation in Pseudophakic Eyes

noAdvanced IOLs with circumferential zones of different power provide pseudoaccommodation. We investigated the potential for power variation with meridian, namely astigmatism, to provide pseudo-accommodation. With appropriate power and axis orientations, acceptable pseudo-accommodation can be achieved

Capecitabine-induced cardiotoxicity: More evidence or clinical approaches to protect the patients' heart?

Fluoropyrimidines, such as capecitabine and 5-fluorouracil, may cause cardiac toxicity. In recent years, the incidence of this side effect has increased and it is expected to further rise due to the population aging and the disproportionate incidence of breast and gastrointestinal cancers in older individuals. The spectrum of cardiac manifestations includes different signs and symptoms and the diagnosis may be difficult. Here, we report the case of a 43-year-old woman with advanced breast cancer who was rechallenged with a capecitabine-based regimen after experiencing a cardiac adverse event during the first fluoropyrimidine exposure. This real-practice case serves as a springboard for discussion about the current evidence on differential diagnosis of capecitabine-related cardiac toxicity, its risk factors, and the underpinning mechanisms of early onset. Moreover, we discussed whether a rechallenge with fluoropyrimidines could be safe in patients who had experienced a previous cardiac adverse even

A Goal-Oriented Approach for Adaptive SLA Monitoring : a Cloud Provider Case Study

National audienceWe argue in this paper that autonomic systems need to make their integrated monitoring adaptive in order to improve their “comprehensive” Quality of Service (QoS). We propose to design this adaptation based on high level objectives (called goals) related to the management of both the “functional system QoS” and the “monitoring system QoS”. Starting from some previous works suggesting a model-driven adaptable monitoring framework composed of 3 layers (configurability, adaptability, governability), we introduce a methodology to identify the functional and monitoring high level goals (according to the agreed Service Level Agreement - SLA) in order to drive models' instantiation. This proposal is first applied to a cloud provider case study for which two high level goals are developed (respect metrics freshness and minimize monitoring cost), and then simulated to show how the quality of management decisions, as well as intelligent monitoring of dynamic SLA, could be improved

Induction motor diagnosis by advanced notch FIR filters and the wigner-ville distribution

During the last years, several time-frequency decomposition tools have been applied for the diagnosis of induction motors, for those cases in which the traditional procedures, such as motor current signature analysis, cannot yield the necessary response. Among them, the Cohen distributions have been widely selected to study transient and even stationary operation due to their high-resolution and detailed information provided at all frequencies. Their main drawback, the cross-terms, has been tackled either modifying the distribution, or carrying out a pretreatment of the signal before computing its time-frequency decomposition. In this paper, a filtering process is proposed that uses advanced notch filters in order to remove constant frequency components present in the current of an induction motor, prior to the computation of its distribution, to study rotor asymmetries and mixed eccentricities. In transient operation of machines directly connected to the grid, this procedure effectively eliminates most of the artifacts that have prevented the use of these tools, allowing a wideband analysis and the definition of a precise quantification parameter able to follow the evolution of their state. © 1982-2012 IEEE

Aerospace Medicine and Biology: A continuing bibliography with indexes, supplement 144

This bibliography lists 257 reports, articles, and other documents introduced into the NASA scientific and technical information system in July 1975

Applications and Experiences of Quality Control

The rich palette of topics set out in this book provides a sufficiently broad overview of the developments in the field of quality control. By providing detailed information on various aspects of quality control, this book can serve as a basis for starting interdisciplinary cooperation, which has increasingly become an integral part of scientific and applied research

The Prototype of Software System of Neural Network Control of Telemetry Data

This paper describes a prototype of software system of neural network control of telemetry data for malfunction diagnosis of spacecraft subsystems. The prototype is used for testing of intelligent technologies for processing information about a spacecraft subsystems state, prediction and detection of irregularities of the spacecraft subsystem modes. The Information obtained from on-board data sources on space communication channel is used for processing