854 research outputs found

    MOMIS: Exploiting agents to support information integration

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    Information overloading introduced by the large amount of data that is spread over the Internet must be faced in an appropriate way. The dynamism and the uncertainty of the Internet, along with the heterogeneity of the sources of information are the two main challenges for today's technologies related to information management. In the area of information integration, this paper proposes an approach based on mobile software agents integrated in the MOMIS (Mediator envirOnment for Multiple Information Sources) infrastructure, which enables semi-automatic information integration to deal with the integration and query of multiple, heterogeneous information sources (relational, object, XML and semi-structured sources). The exploitation of mobile agents in MOMIS can significantly increase the flexibility of the system. In fact, their characteristics of autonomy and adaptability well suit the distributed and open environments, such as the Internet. The aim of this paper is to show the advantages of the introduction in the MOMIS infrastructure of intelligent and mobile software agents for the autonomous management and coordination of integration and query processing over heterogeneous data sources

    Tools for knowledge acquisition within the NeuroScholar system and their application to anatomical tract-tracing data

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    BACKGROUND: Knowledge bases that summarize the published literature provide useful online references for specific areas of systems-level biology that are not otherwise supported by large-scale databases. In the field of neuroanatomy, groups of small focused teams have constructed medium size knowledge bases to summarize the literature describing tract-tracing experiments in several species. Despite years of collation and curation, these databases only provide partial coverage of the available published literature. Given that the scientists reading these papers must all generate the interpretations that would normally be entered into such a system, we attempt here to provide general-purpose annotation tools to make it easy for members of the community to contribute to the task of data collation. RESULTS: In this paper, we describe an open-source, freely available knowledge management system called 'NeuroScholar' that allows straightforward structured markup of the PDF files according to a well-designed schema to capture the essential details of this class of experiment. Although, the example worked through in this paper is quite specific to neuroanatomical connectivity, the design is freely extensible and could conceivably be used to construct local knowledge bases for other experiment types. Knowledge representations of the experiment are also directly linked to the contributing textual fragments from the original research article. Through the use of this system, not only could members of the community contribute to the collation task, but input data can be gathered for automated approaches to permit knowledge acquisition through the use of Natural Language Processing (NLP). CONCLUSION: We present a functional, working tool to permit users to populate knowledge bases for neuroanatomical connectivity data from the literature through the use of structured questionnaires. This system is open-source, fully functional and available for download from [1]

    Knowledge-based support for object-oriented design

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    The research is conducted in the area of Software Engineering, with emphasis on the design phase of the Software Development Life Cycle (SDLC). The object-oriented paradigm is the point of departure. The investigation deals with the problem of creating support for the design phase of object-oriented system development. This support must be able to guide the system designer through the design process, according to a sound design method, highlight opportunities for prototyping and point out where to re-iterate a design step, for example. A solution is proposed in the form of a knowledge-based support system. In the prototype this support guides a designer partially through the first step of the System Design task for object-oriented design. The intention is that the knowledge-based system should capture the know-how of an expert system designer and assist an inexperienced system designer to create good designs.ComputingM. Sc. (Information Systems

    DFKI publications : the first four years ; 1990 - 1993

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    Clinical foundations and information architecture for the implementation of a federated health record service

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    Clinical care increasingly requires healthcare professionals to access patient record information that may be distributed across multiple sites, held in a variety of paper and electronic formats, and represented as mixtures of narrative, structured, coded and multi-media entries. A longitudinal person-centred electronic health record (EHR) is a much-anticipated solution to this problem, but its realisation is proving to be a long and complex journey. This Thesis explores the history and evolution of clinical information systems, and establishes a set of clinical and ethico-legal requirements for a generic EHR server. A federation approach (FHR) to harmonising distributed heterogeneous electronic clinical databases is advocated as the basis for meeting these requirements. A set of information models and middleware services, needed to implement a Federated Health Record server, are then described, thereby supporting access by clinical applications to a distributed set of feeder systems holding patient record information. The overall information architecture thus defined provides a generic means of combining such feeder system data to create a virtual electronic health record. Active collaboration in a wide range of clinical contexts, across the whole of Europe, has been central to the evolution of the approach taken. A federated health record server based on this architecture has been implemented by the author and colleagues and deployed in a live clinical environment in the Department of Cardiovascular Medicine at the Whittington Hospital in North London. This implementation experience has fed back into the conceptual development of the approach and has provided "proof-of-concept" verification of its completeness and practical utility. This research has benefited from collaboration with a wide range of healthcare sites, informatics organisations and industry across Europe though several EU Health Telematics projects: GEHR, Synapses, EHCR-SupA, SynEx, Medicate and 6WINIT. The information models published here have been placed in the public domain and have substantially contributed to two generations of CEN health informatics standards, including CEN TC/251 ENV 13606

    Towards a framework for engineering big data: An automotive systems perspective

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    noDemand for more sophisticated models to meet big data expectations require significant data repository obligations, operating concurrently in higher-level applications. Current models provide only disjointed modelling paradigms. The proposed framework addresses the need for higher-level abstraction, using low-level logic in the form of axioms, from which higher-level functionality is logically derived. The framework facilitates definition and usage of subjective structures across the cyber-physical system domain, and is intended to converge the range of heterogeneous data-driven objects
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