93,133 research outputs found
Ontology-assisted database integration to support natural language processing and biomedical data-mining
Successful biomedical data mining and information extraction require a complete picture of biological phenomena such as genes, biological processes, and diseases; as these exist on different levels of granularity. To realize this goal, several freely available heterogeneous databases as well as proprietary structured datasets have to be integrated into a single global customizable scheme. We will present a tool to integrate different biological data sources by mapping them to a proprietary biomedical ontology that has been developed for the purposes of making computers understand medical natural language
Technology Integration around the Geographic Information: A State of the Art
One of the elements that have popularized and facilitated the use of geographical information on a variety of computational applications has been the use of Web maps; this has opened new research challenges on different subjects, from locating places and people, the study of social behavior or the analyzing of the hidden structures of the terms used in a natural language query used for locating a place. However, the use of geographic information under technological features is not new, instead it has been part of a development and technological integration process. This paper presents a state of the art review about the application of geographic information under different approaches: its use on location based services, the collaborative user participation on it, its contextual-awareness, its use in the Semantic Web and the challenges of its use in natural languge queries. Finally, a prototype that integrates most of these areas is presented
Nucleotide second messengers in bacterial decision making
Since the initial discovery of bacterial nucleotide second messengers (NSMs), we have made huge progress towards understanding these complex signalling networks. Many NSM networks contain dozens of metabolic enzymes and binding targets, whose activity is tightly controlled at every regulatory level. They function as global regulators and in specific signalling circuits, controlling multiple aspects of bacterial behaviour and development. Despite these advances there is much still to discover, with current research focussing on the molecular mechanisms of signalling circuits, the role of the environment in controlling NSM pathways and attempts to understand signalling at the whole cell/community level. Here we examine recent developments in the NSM signalling field and discuss their implications for understanding this important driver of microbial behaviour
How can heat maps of indexing vocabularies be utilized for information seeking purposes?
The ability to browse an information space in a structured way by exploiting
similarities and dissimilarities between information objects is crucial for
knowledge discovery. Knowledge maps use visualizations to gain insights into
the structure of large-scale information spaces, but are still far away from
being applicable for searching. The paper proposes a use case for enhancing
search term recommendations by heat map visualizations of co-word
relation-ships taken from indexing vocabulary. By contrasting areas of
different "heat" the user is enabled to indicate mainstream areas of the field
in question more easily.Comment: URL workshop proceedings: http://ceur-ws.org/Vol-1311
Stone tools and the linguistic capabilities of earlier hominids
The evolution of human manipulative abilities may be clearly linked to the evolution of speech motor control Both creativity and complexity in vocal and manipulative gestures may be closely linked to a single dimension of brain evolution — the evolution of absolute brain size. Inferring the linguistic capabilities of earlier hominids from their lithic artefacts, however, required us to take account of domain-specific constraints on manipulative skill In this article we report on a pilot flint-knapping experiment designed to identify such constraints ‘in action’
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Making hurricane track data accessible
Our interactive tool allows the exploration, validation and presentation of hundreds of years of dynamically simulated storm tracks. The tracks were generated as part of a research project to improve the risk assessment of tropical storm damage by the insurance industry. The main impact of the tool is that exploratory interactive visualisation is now being used by the storm track modellers to (a) validate and improve model outputs, (b) discuss outputs with their peers (c) obtain a better understanding of the formation and development of tropical storms and (d) present examples of the behaviour of storms under different conditions to the insurance industry and others. Insights into tropical storm behaviour have been obtained and these insights are being articulated
Designing as Construction of Representations: A Dynamic Viewpoint in Cognitive Design Research
This article presents a cognitively oriented viewpoint on design. It focuses
on cognitive, dynamic aspects of real design, i.e., the actual cognitive
activity implemented by designers during their work on professional design
projects. Rather than conceiving de-signing as problem solving - Simon's
symbolic information processing (SIP) approach - or as a reflective practice or
some other form of situated activity - the situativity (SIT) approach - we
consider that, from a cognitive viewpoint, designing is most appropriately
characterised as a construction of representations. After a critical discussion
of the SIP and SIT approaches to design, we present our view-point. This
presentation concerns the evolving nature of representations regarding levels
of abstraction and degrees of precision, the function of external
representations, and specific qualities of representation in collective design.
Designing is described at three levels: the organisation of the activity, its
strategies, and its design-representation construction activities (different
ways to generate, trans-form, and evaluate representations). Even if we adopt a
"generic design" stance, we claim that design can take different forms
depending on the nature of the artefact, and we propose some candidates for
dimensions that allow a distinction to be made between these forms of design.
We discuss the potential specificity of HCI design, and the lack of cognitive
design research occupied with the quality of design. We close our discussion of
representational structures and activities by an outline of some directions
regarding their functional linkages
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