21,968 research outputs found

    A Joint Model for Definition Extraction with Syntactic Connection and Semantic Consistency

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    Definition Extraction (DE) is one of the well-known topics in Information Extraction that aims to identify terms and their corresponding definitions in unstructured texts. This task can be formalized either as a sentence classification task (i.e., containing term-definition pairs or not) or a sequential labeling task (i.e., identifying the boundaries of the terms and definitions). The previous works for DE have only focused on one of the two approaches, failing to model the inter-dependencies between the two tasks. In this work, we propose a novel model for DE that simultaneously performs the two tasks in a single framework to benefit from their inter-dependencies. Our model features deep learning architectures to exploit the global structures of the input sentences as well as the semantic consistencies between the terms and the definitions, thereby improving the quality of the representation vectors for DE. Besides the joint inference between sentence classification and sequential labeling, the proposed model is fundamentally different from the prior work for DE in that the prior work has only employed the local structures of the input sentences (i.e., word-to-word relations), and not yet considered the semantic consistencies between terms and definitions. In order to implement these novel ideas, our model presents a multi-task learning framework that employs graph convolutional neural networks and predicts the dependency paths between the terms and the definitions. We also seek to enforce the consistency between the representations of the terms and definitions both globally (i.e., increasing semantic consistency between the representations of the entire sentences and the terms/definitions) and locally (i.e., promoting the similarity between the representations of the terms and the definitions)

    Accurate De Novo Prediction of Protein Contact Map by Ultra-Deep Learning Model

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    Recently exciting progress has been made on protein contact prediction, but the predicted contacts for proteins without many sequence homologs is still of low quality and not very useful for de novo structure prediction. This paper presents a new deep learning method that predicts contacts by integrating both evolutionary coupling (EC) and sequence conservation information through an ultra-deep neural network formed by two deep residual networks. This deep neural network allows us to model very complex sequence-contact relationship as well as long-range inter-contact correlation. Our method greatly outperforms existing contact prediction methods and leads to much more accurate contact-assisted protein folding. Tested on three datasets of 579 proteins, the average top L long-range prediction accuracy obtained our method, the representative EC method CCMpred and the CASP11 winner MetaPSICOV is 0.47, 0.21 and 0.30, respectively; the average top L/10 long-range accuracy of our method, CCMpred and MetaPSICOV is 0.77, 0.47 and 0.59, respectively. Ab initio folding using our predicted contacts as restraints can yield correct folds (i.e., TMscore>0.6) for 203 test proteins, while that using MetaPSICOV- and CCMpred-predicted contacts can do so for only 79 and 62 proteins, respectively. Further, our contact-assisted models have much better quality than template-based models. Using our predicted contacts as restraints, we can (ab initio) fold 208 of the 398 membrane proteins with TMscore>0.5. By contrast, when the training proteins of our method are used as templates, homology modeling can only do so for 10 of them. One interesting finding is that even if we do not train our prediction models with any membrane proteins, our method works very well on membrane protein prediction. Finally, in recent blind CAMEO benchmark our method successfully folded 5 test proteins with a novel fold

    An attentive neural architecture for joint segmentation and parsing and its application to real estate ads

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    In processing human produced text using natural language processing (NLP) techniques, two fundamental subtasks that arise are (i) segmentation of the plain text into meaningful subunits (e.g., entities), and (ii) dependency parsing, to establish relations between subunits. In this paper, we develop a relatively simple and effective neural joint model that performs both segmentation and dependency parsing together, instead of one after the other as in most state-of-the-art works. We will focus in particular on the real estate ad setting, aiming to convert an ad to a structured description, which we name property tree, comprising the tasks of (1) identifying important entities of a property (e.g., rooms) from classifieds and (2) structuring them into a tree format. In this work, we propose a new joint model that is able to tackle the two tasks simultaneously and construct the property tree by (i) avoiding the error propagation that would arise from the subtasks one after the other in a pipelined fashion, and (ii) exploiting the interactions between the subtasks. For this purpose, we perform an extensive comparative study of the pipeline methods and the new proposed joint model, reporting an improvement of over three percentage points in the overall edge F1 score of the property tree. Also, we propose attention methods, to encourage our model to focus on salient tokens during the construction of the property tree. Thus we experimentally demonstrate the usefulness of attentive neural architectures for the proposed joint model, showcasing a further improvement of two percentage points in edge F1 score for our application.Comment: Preprint - Accepted for publication in Expert Systems with Application
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