Improvisation of classification performance based on feature optimization for differentiation of Parkinson’s disease from other neurological diseases using gait characteristics

Most neurological disorders that include Parkinson’s disease (PD) as well as other neurological diseases such as Amyotrophic Lateral Sclerosis (ALS) and Huntington’s disease (HD) have some common abnormalities regarding the movement, vocal, and cognitive behaviors of sufferers. Variations in the manifestation of these types of abnormality help distinguish one disorder from another. In this study, differentiation was performed based on the gait characteristics of patients afflicted by different neurological disorders. In the recent past, many researchers have applied different machine learning and feature selection techniques to the classification of different groups of patients based on common abnormalities. However, in an era of modernization where the focus is on timely low-cost automatization and pattern recognition, such techniques require improvisation to provide high performance. We attempted to improve the performance of such techniques using different feature optimization methods, such as a genetic algorithm (GA) and principal component analysis (PCA), and applying different classification approaches, i.e., linear, nonlinear, and probabilistic classifiers. In this study, gait dynamics data of patients suffering with PD, ALS, and HD were collated from a public database, and a binary classification approach was used by taking PD as one group and adopting ALS+HD as another group. Performance comparison was achieved using different classification techniques that incorporated optimized feature sets obtained from GA and PCA. In comparison with other classifiers using different feature sets, the highest accuracy (97.87%) was obtained using random forest combined with GA-based feature sets. The results provide evidence that could assist medical practitioners in differentiating PD from other neurological diseases using gait characteristics

Development of an integrated decision support system for supporting offshore oil spill response in harsh environments

Offshore oil spills can lead to significantly negative impacts on socio-economy and constitute a direct hazard to the marine environment and human health. The response to an oil spill usually consists of a series of dynamic, time-sensitive, multi-faceted and complex processes subject to various constraints and challenges. In the past decades, many models have been developed mainly focusing on individual processes including oil weathering simulation, impact assessment, and clean-up optimization. However, to date, research on integration of offshore oil spill vulnerability analysis, process simulation and operation optimization is still lacking. Such deficiency could be more influential in harsh environments. It becomes noticeably critical and urgent to develop new methodologies and improve technical capacities of offshore oil spill responses. Therefore, this proposed research aims at developing an integrated decision support system for supporting offshore oil spill responses especially in harsh environments (DSS-OSRH). Such a DSS consists of offshore oil spill vulnerability analysis, response technologies screening, and simulation-optimization coupling. The uncertainties and/or dynamics have been quantitatively reflected throughout the modeling processes. First, a Monte Carlo simulation based two-stage adaptive resonance theory mapping (MC-TSAM) approach has been developed. A real-world case study was applied for offshore oil spill vulnerability index (OSVI) classification in the south coast of Newfoundland to demonstrate this approach. Furthermore, a Monte Carlo simulation based integrated rule-based fuzzy adaptive resonance theory mapping (MC-IRFAM) approach has been developed for screening and ranking for spill response and clean-up technologies. The feasibility of the MC-IRFAM was tested with a case of screening and ranking response technologies in an offshore oil spill event. A novel Monte Carlo simulation based dynamic mixed integer nonlinear programming (MC-DMINP) approach has also been developed for the simulation-optimization coupling in offshore oil spill responses. To demonstrate this approach, a case study was conducted in device allocation and oil recovery in an offshore oil spill event. Finally, the DSS-OSRH has been developed based on the integration of MC-TSAM, MC-IRFAM, AND MC-DSINP. To demonstrate its feasibility, a case study was conducted in the decision support during offshore oil spill response in the south coast of Newfoundland. The developed approaches and DSS are the first of their kinds to date targeting offshore oil spill responses. The novelty can be reflected from the following aspects: 1) an innovative MC-TSAM approach for offshore OSVI classification under complexity and uncertainty; 2) a new MC-IRFAM approach for oil spill response technologies classification and ranking with uncertain information; 3) a novel MC-DMINP simulation-optimization coupling approach for offshore oil spill response operation and resource allocation under uncertainty; and 4) an innovational DSS-OSRH which consists of the MC-TSAM, MC-IRFAM, MC-DMINP, supporting decision making throughout the offshore oil spill response processes. These methods are particularly suitable for offshore oil spill responses in harsh environments such as the offshore areas of Newfoundland and Labrador (NL). The research will also promote the understanding of the processes of oil transport and fate and the impacts to the affected offshore and shoreline area. The methodologies will be capable of providing modeling tools for other related areas that require timely and effective decisions under complexity and uncertainty

Perspectives on Public Policy in Societal-Environmental Crises

This is an open access book. Histories we tell never emerge in a vacuum, and history as an academic discipline that studies the past is highly sensitive to the concerns of the present and the heated debates that can divide entire societies. But does the study of the past also have something to teach us about the future? Can history help us in coping with the planetary crisis we are now facing? By analyzing historical societies as complex adaptive systems, we contribute to contemporary thinking about societal-environmental interactions in policy and planning and consider how environmental and climatic changes, whether sudden high impact events or more subtle gradual changes, impacted human responses in the past. We ask how societal perceptions of such changes affect behavioral patterns and explanatory rationalities in premodernity, and whether a better historical understanding of these relationships can inform our response to contemporary problems of similar nature and magnitude, such as adapting to climate change

Anales del XIII Congreso Argentino de Ciencias de la Computación (CACIC)

Contenido: Arquitecturas de computadoras Sistemas embebidos Arquitecturas orientadas a servicios (SOA) Redes de comunicaciones Redes heterogéneas Redes de Avanzada Redes inalámbricas Redes móviles Redes activas Administración y monitoreo de redes y servicios Calidad de Servicio (QoS, SLAs) Seguridad informática y autenticación, privacidad Infraestructura para firma digital y certificados digitales Análisis y detección de vulnerabilidades Sistemas operativos Sistemas P2P Middleware Infraestructura para grid Servicios de integración (Web Services o .Net)Red de Universidades con Carreras en Informática (RedUNCI

Anales del XIII Congreso Argentino de Ciencias de la Computación (CACIC)

Contenido: Arquitecturas de computadoras Sistemas embebidos Arquitecturas orientadas a servicios (SOA) Redes de comunicaciones Redes heterogéneas Redes de Avanzada Redes inalámbricas Redes móviles Redes activas Administración y monitoreo de redes y servicios Calidad de Servicio (QoS, SLAs) Seguridad informática y autenticación, privacidad Infraestructura para firma digital y certificados digitales Análisis y detección de vulnerabilidades Sistemas operativos Sistemas P2P Middleware Infraestructura para grid Servicios de integración (Web Services o .Net)Red de Universidades con Carreras en Informática (RedUNCI

String Grammar Unsupervised Possibilistic Fuzzy C-Medians for Gait Pattern Classification in Patients with Neurodegenerative Diseases

Neurodegenerative diseases that affect serious gait abnormalities include Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS), and Huntington disease (HD). These diseases lead to gait rhythm distortion that can be determined by stride time interval of footfall contact times. In this paper, we present a new method for gait classification of neurodegenerative diseases. In particular, we utilize a symbolic aggregate approximation algorithm to convert left-foot stride-stride interval into a sequence of symbols using a symbolic aggregate approximation. We then find string prototypes of each class using the newly proposed string grammar unsupervised possibilistic fuzzy C-medians. Then in the testing process the fuzzy k-nearest neighbor is used. We implement the system on three 2-class problems, i.e., the classification of ALS against healthy patients, that of HD against healthy patients , and that of PD against healthy patients. The system is also implemented on one 4-class problem (the classification of ALS, HD, PD, and healthy patients altogether) called NDDs versus healthy. We found that our system yields a very good detection result. The average correct classification for ALS versus healthy is 96.88%, and that for HD versus healthy is 97.22%, whereas that for PD versus healthy is 96.43%. When the system is implemented on 4-class problem, the average accuracy is approximately 98.44%. It can provide prototypes of gait signals that are more understandable to human