6,821 research outputs found

    UMSL Bulletin 2023-2024

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    The 2023-2024 Bulletin and Course Catalog for the University of Missouri St. Louis.https://irl.umsl.edu/bulletin/1088/thumbnail.jp

    Southern Adventist University Undergraduate Catalog 2022-2023

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    Southern Adventist University\u27s undergraduate catalog for the academic year 2022-2023.https://knowledge.e.southern.edu/undergrad_catalog/1121/thumbnail.jp

    Towards a tricorder: clinical, health economic, and ethical investigation of point-of-care artificial intelligence electrocardiogram for heart failure

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    Heart failure (HF) is an international public health priority and a focus of the NHS Long Term Plan. There is a particular need in primary care for screening and early detection of heart failure with reduced ejection fraction (HFrEF) – the most common and serious HF subtype, and the only one with an abundant evidence base for effective therapies. Digital health technologies (DHTs) integrating artificial intelligence (AI) could improve diagnosis of HFrEF. Specifically, through a convergence of DHTs and AI, a single-lead electrocardiogram (ECG) can be recorded by a smart stethoscope and interrogated by AI (AI-ECG) to potentially serve as a point-of-care HFrEF test. However, there are concerning evidence gaps for such DHTs applying AI; across intersecting clinical, health economic, and ethical considerations. My thesis therefore investigates hypotheses that AI-ECG is 1.) Reliable, accurate, unbiased, and can be patient self-administered, 2.) Of justifiable health economic impact for primary care deployment, and 3.) Appropriate across ethical domains for deployment as a tool for patient self-administered screening. The theoretical basis for this work is presented in the Introduction (Chapter 1). Chapter 2 describes the first large-scale, multi-centre independent external validation study of AI-ECG, prospectively recruiting 1,050 patients and highlighting impressive performance: area under the curve, sensitivity, and specificity up to 0·91 (95% confidence interval: 0·88–0·95), 91·9% (78·1–98·3), and 80·2% (75·5–84·3) respectively; and absence of bias by age, sex, and ethnicity. Performance was independent of operator, and usability of the tool extended to patients being able to self-examine. Chapter 3 presents a clinical and health economic outcomes analysis using a contemporary digital repository of 2.5 million NHS patient records. A propensity-matched cohort was derived using all patients diagnosed with HF from 2015-2020 (n = 34,208). Novel findings included the unacceptable reality that 70% of index HF diagnoses are made through hospitalisation; where index diagnosis through primary care conferred a medium-term survival advantage and long-term cost saving (£2,500 per patient). This underpins a health economic model for the deployment of AI-ECG across primary care. Chapter 4 approaches a normative ethical analysis focusing on equity, agency, data rights, and responsibility for safe, effective, and trustworthy implementation of an unprecedented at-home patient self-administered AI-ECG screening programme. I propose approaches to mitigating any potential harms, towards preserving and promoting trust, patient engagement, and public health. Collectively, this thesis marks novel work highlighting AI-ECG as tool with the potential to address major cardiovascular public health priorities. Scrutiny through complimentary clinical, health economic, and ethical considerations can directly serve patients and health systems by blueprinting best-practice for the evaluation and implementation of DHTs integrating AI – building the conviction needed to realise the full potential of such technologies.Open Acces

    Life Satisfaction and Psychological and Physical Well-Being

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    A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section Health-Related Quality of Life and Well-Being . It showcases a review and empirical studies on life satisfaction and its related aspects. The studies are from several countries on a wide range of samples including university students, faculty, nurses, entrepreneurs, adolescents, national databases, refugees, and community samples Prof. Dr. V. K. KumarProf. Dr. Jasmin Tahmaseb-McConathaGuest Editorshttps://digitalcommons.wcupa.edu/ctsmfaculty_books/1028/thumbnail.jp

    Dialogue without barriers. A comprehensive approach to dealing with stuttering

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    2023-2024 Boise State University Undergraduate Catalog

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    This catalog is primarily for and directed at students. However, it serves many audiences, such as high school counselors, academic advisors, and the public. In this catalog you will find an overview of Boise State University and information on admission, registration, grades, tuition and fees, financial aid, housing, student services, and other important policies and procedures. However, most of this catalog is devoted to describing the various programs and courses offered at Boise State

    A discourse analysis of Lacanian psychoanalysts conceptualisation of child psychopathology

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    This study explores how Lacanian Psychoanalysts understand child psychopathology. Addressing this question in line with the principles of the methodological approach that was adopted for the study meant conducting a review of the literature pertaining to the dominant discourses that construct the concepts ‘child’ and ‘psychopathology’. The discourses found to be most influentially to the construction of childhood, historically and contemporaneously, were those of religion, philosophy, and developmental psychology. A review of the literature concerning psychopathology revealed how developmental psychopathology and psychiatry remain the dominant models in research and the clinical treatment of children experiencing mental health problems. The most prominent methods of clinical treatment are also addressed as part of the literature review. This served as the backdrop against which the subject of Lacanian psychoanalysis with children is being explored. Lacanian psychoanalysis provides a coherent theory, with an emphasis on subjectivity, the unconscious, discourse and early childhood as factors that structure the individual. It is these elements that enable practitioners to conduct a form of treatment that is described as ‘one-by-one’, always unique and original to each case. Six semi-structured interviews were carried out with the participants and the interview data was transcribed and analysed using Foucauldian Discourse Analysis (FDA). FDA was used to explore how the participants constructed their understanding of child psychopathology by paying attention to the discourses they used in discussing this subject. The study outlines the role of contemporary culture in the conceptualisation of childhood and psychopathology according to the participants and reveals a radically different way of conducting treatment to the dominant models, those that are addressed in the literature review. These findings from the study advocate for a more nuanced approach to treating children with mental health difficulties that recognises the unique individual qualities of each child and takes account of their social and cultural experience in devising and delivering programmes of treatment
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