6,821 research outputs found
UMSL Bulletin 2023-2024
The 2023-2024 Bulletin and Course Catalog for the University of Missouri St. Louis.https://irl.umsl.edu/bulletin/1088/thumbnail.jp
Southern Adventist University Undergraduate Catalog 2022-2023
Southern Adventist University\u27s undergraduate catalog for the academic year 2022-2023.https://knowledge.e.southern.edu/undergrad_catalog/1121/thumbnail.jp
Towards a tricorder: clinical, health economic, and ethical investigation of point-of-care artificial intelligence electrocardiogram for heart failure
Heart failure (HF) is an international public health priority and a focus of the NHS Long Term
Plan. There is a particular need in primary care for screening and early detection of heart failure with
reduced ejection fraction (HFrEF) – the most common and serious HF subtype, and the only one
with an abundant evidence base for effective therapies. Digital health technologies (DHTs) integrating
artificial intelligence (AI) could improve diagnosis of HFrEF. Specifically, through a convergence of
DHTs and AI, a single-lead electrocardiogram (ECG) can be recorded by a smart stethoscope and
interrogated by AI (AI-ECG) to potentially serve as a point-of-care HFrEF test. However, there are
concerning evidence gaps for such DHTs applying AI; across intersecting clinical, health economic,
and ethical considerations. My thesis therefore investigates hypotheses that AI-ECG is 1.) Reliable,
accurate, unbiased, and can be patient self-administered, 2.) Of justifiable health economic impact for
primary care deployment, and 3.) Appropriate across ethical domains for deployment as a tool for
patient self-administered screening. The theoretical basis for this work is presented in the Introduction (Chapter 1). Chapter 2 describes the first large-scale, multi-centre independent external validation study of AI-ECG, prospectively recruiting 1,050 patients and highlighting impressive performance: area under the curve, sensitivity, and specificity up to 0·91 (95% confidence interval: 0·88–0·95), 91·9% (78·1–98·3), and
80·2% (75·5–84·3) respectively; and absence of bias by age, sex, and ethnicity. Performance was
independent of operator, and usability of the tool extended to patients being able to self-examine.
Chapter 3 presents a clinical and health economic outcomes analysis using a contemporary digital
repository of 2.5 million NHS patient records. A propensity-matched cohort was derived using all
patients diagnosed with HF from 2015-2020 (n = 34,208). Novel findings included the unacceptable
reality that 70% of index HF diagnoses are made through hospitalisation; where index diagnosis through primary care conferred a medium-term survival advantage and long-term cost saving (£2,500
per patient). This underpins a health economic model for the deployment of AI-ECG across primary
care. Chapter 4 approaches a normative ethical analysis focusing on equity, agency, data rights, and
responsibility for safe, effective, and trustworthy implementation of an unprecedented at-home patient
self-administered AI-ECG screening programme. I propose approaches to mitigating any potential
harms, towards preserving and promoting trust, patient engagement, and public health.
Collectively, this thesis marks novel work highlighting AI-ECG as tool with the potential to
address major cardiovascular public health priorities. Scrutiny through complimentary clinical, health
economic, and ethical considerations can directly serve patients and health systems by blueprinting
best-practice for the evaluation and implementation of DHTs integrating AI – building the conviction
needed to realise the full potential of such technologies.Open Acces
Life Satisfaction and Psychological and Physical Well-Being
A special issue of International Journal of Environmental Research and Public Health (ISSN 1660-4601). This special issue belongs to the section Health-Related Quality of Life and Well-Being . It showcases a review and empirical studies on life satisfaction and its related aspects. The studies are from several countries on a wide range of samples including university students, faculty, nurses, entrepreneurs, adolescents, national databases, refugees, and community samples
Prof. Dr. V. K. KumarProf. Dr. Jasmin Tahmaseb-McConathaGuest Editorshttps://digitalcommons.wcupa.edu/ctsmfaculty_books/1028/thumbnail.jp
2023-2024 Boise State University Undergraduate Catalog
This catalog is primarily for and directed at students. However, it serves many audiences, such as high school counselors, academic advisors, and the public. In this catalog you will find an overview of Boise State University and information on admission, registration, grades, tuition and fees, financial aid, housing, student services, and other important policies and procedures. However, most of this catalog is devoted to describing the various programs and courses offered at Boise State
A discourse analysis of Lacanian psychoanalysts conceptualisation of child psychopathology
This study explores how Lacanian Psychoanalysts understand child psychopathology.
Addressing this question in line with the principles of the methodological approach that was
adopted for the study meant conducting a review of the literature pertaining to the dominant
discourses that construct the concepts ‘child’ and ‘psychopathology’. The discourses found
to be most influentially to the construction of childhood, historically and
contemporaneously, were those of religion, philosophy, and developmental psychology. A
review of the literature concerning psychopathology revealed how developmental
psychopathology and psychiatry remain the dominant models in research and the clinical
treatment of children experiencing mental health problems. The most prominent methods of
clinical treatment are also addressed as part of the literature review. This served as the
backdrop against which the subject of Lacanian psychoanalysis with children is being
explored. Lacanian psychoanalysis provides a coherent theory, with an emphasis on
subjectivity, the unconscious, discourse and early childhood as factors that structure the
individual. It is these elements that enable practitioners to conduct a form of treatment that
is described as ‘one-by-one’, always unique and original to each case. Six semi-structured
interviews were carried out with the participants and the interview data was transcribed and
analysed using Foucauldian Discourse Analysis (FDA). FDA was used to explore how the
participants constructed their understanding of child psychopathology by paying attention to
the discourses they used in discussing this subject. The study outlines the role of
contemporary culture in the conceptualisation of childhood and psychopathology according
to the participants and reveals a radically different way of conducting treatment to the
dominant models, those that are addressed in the literature review. These findings from the
study advocate for a more nuanced approach to treating children with mental health
difficulties that recognises the unique individual qualities of each child and takes account of
their social and cultural experience in devising and delivering programmes of treatment
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