Human behavioural analysis with self-organizing map for ambient assisted living

This paper presents a system for automatically classifying the resting location of a moving object in an indoor environment. The system uses an unsupervised neural network (Self Organising Feature Map) fully implemented on a low-cost, low-power automated home-based surveillance system, capable of monitoring activity level of elders living alone independently. The proposed system runs on an embedded platform with a specialised ceiling-mounted video sensor for intelligent activity monitoring. The system has the ability to learn resting locations, to measure overall activity levels and to detect specific events such as potential falls. First order motion information, including first order moving average smoothing, is generated from the 2D image coordinates (trajectories). A novel edge-based object detection algorithm capable of running at a reasonable speed on the embedded platform has been developed. The classification is dynamic and achieved in real-time. The dynamic classifier is achieved using a SOFM and a probabilistic model. Experimental results show less than 20% classification error, showing the robustness of our approach over others in literature with minimal power consumption. The head location of the subject is also estimated by a novel approach capable of running on any resource limited platform with power constraints

Design and Optimizing of On-Chip Kinesin Substrates for Molecular Communication

Lab-on-chip devices and point-of-care diagnostic chip devices are composed of many different components such as nanosensors that must be able to communicate with other components within the device. Molecular communication is a promising solution for on-chip communication. In particular, kinesin driven microtubule (MT) motility is an effective means of transferring information particles from one component to another. However, finding an optimal shape for these channels can be challenging. In this paper we derive a mathematical optimization model that can be used to find the optimal channel shape and dimensions for any transmission period. We derive three specific models for the rectangular channels, regular polygonal channels, and regular polygonal ring channels. We show that the optimal channel shapes are the square-shaped channel for the rectangular channel, and circular-shaped channel for the other classes of shapes. Finally, we show that among all 2 dimensional shapes the optimal design choice that maximizes information rate is the circular-shaped channel.Comment: accepted for publication in IEEE Transactions on Nanotechnolog

Contactless acoustic micro/nano manipulation:a paradigm for next generation applications in life sciences

Acoustic actuation techniques offer a promising tool for contactless manipulation of both synthetic and biological micro/nano agents that encompass different length scales. The traditional usage of sound waves has steadily progressed from mid-air manipulation of salt grains to sophisticated techniques that employ nanoparticle flow in microfluidic networks. State-of-the-art in microfabrication and instrumentation have further expanded the outreach of these actuation techniques to autonomous propulsion of micro-agents. In this review article, we provide a universal perspective of the known acoustic micromanipulation technologies in terms of their applications and governing physics. Hereby, we survey these technologies and classify them with regards to passive and active manipulation of agents. These manipulation methods account for both intelligent devices adept at dexterous non-contact handling of micro-agents, and acoustically induced mechanisms for self-propulsion of micro-robots. Moreover, owing to the clinical compliance of ultrasound, we provide future considerations of acoustic manipulation techniques to be fruitfully employed in biological applications that range from label-free drug testing to minimally invasive clinical interventions

Interoperable services based on activity monitoring in ambient assisted living environments

Ambient Assisted Living (AAL) is considered as the main technological solution that will enable the aged and people in recovery to maintain their independence and a consequent high quality of life for a longer period of time than would otherwise be the case. This goal is achieved by monitoring human’s activities and deploying the appropriate collection of services to set environmental features and satisfy user preferences in a given context. However, both human monitoring and services deployment are particularly hard to accomplish due to the uncertainty and ambiguity characterising human actions, and heterogeneity of hardware devices composed in an AAL system. This research addresses both the aforementioned challenges by introducing 1) an innovative system, based on Self Organising Feature Map (SOFM), for automatically classifying the resting location of a moving object in an indoor environment and 2) a strategy able to generate context-aware based Fuzzy Markup Language (FML) services in order to maximize the users’ comfort and hardware interoperability level. The overall system runs on a distributed embedded platform with a specialised ceiling- mounted video sensor for intelligent activity monitoring. The system has the ability to learn resting locations, to measure overall activity levels, to detect specific events such as potential falls and to deploy the right sequence of fuzzy services modelled through FML for supporting people in that particular context. Experimental results show less than 20% classification error in monitoring human activities and providing the right set of services, showing the robustness of our approach over others in literature with minimal power consumption

A concise review of microfluidic particle manipulation methods

Particle manipulation is often required in many applications such as bioanalysis, disease diagnostics, drug delivery and self-cleaning surfaces. The fast progress in micro- and nano-engineering has contributed to the rapid development of a variety of technologies to manipulate particles including more established methods based on microfluidics, as well as recently proposed innovative methods that still are in the initial phases of development, based on self-driven microbots and artificial cilia. Here, we review these techniques with respect to their operation principles and main applications. We summarize the shortcomings and give perspectives on the future development of particle manipulation techniques. Rather than offering an in-depth, detailed, and complete account of all the methods, this review aims to provide a broad but concise overview that helps to understand the overall progress and current status of the diverse particle manipulation methods. The two novel developments, self-driven microbots and artificial cilia-based manipulation, are highlighted in more detail