A theoretical and empirical study on unbiased boundary-extended crossover for real-valued representation

Copyright © 2012 Elsevier. NOTICE: this is the author’s version of a work that was accepted for publication in Information Sciences. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Information Sciences Vol. 183 Issue 1 (2012), DOI: 10.1016/j.ins.2011.07.013We present a new crossover operator for real-coded genetic algorithms employing a novel methodology to remove the inherent bias of pre-existing crossover operators. This is done by transforming the topology of the hyper-rectangular real space by gluing opposite boundaries and designing a boundary extension method for making the fitness function smooth at the glued boundary. We show the advantages of the proposed crossover by comparing its performance with those of existing ones on test functions that are commonly used in the literature, and a nonlinear regression on a real-world dataset

Genetic fuzzy system predicting contractile reactivity patterns of small arteries

Monitoring of physiological surrogate end points in drug development generates dynamic time-domain data reflecting the state of the biological system. Conventional data analysis often reduces the information in these data by extracting specific data points, thereby discarding potentially useful information. We developed a genetic fuzzy system (GFS) algorithm that is capable of learning all information in time-domain physiological data. Data on isometric force development of isolated small arteries were used as a framework for developing and optimizing a GFS. GFS performance was improved by several strategies. Results show that optimized fuzzy systems (OFSs) predict contractile reactivity of arteries accurately. In addition, OFSs identified significant differences that were undetectable using conventional analysis in the responses of arteries between groups. We concluded that OFSs may be used in clustering or classification tasks as aids in the objective identification or prediction of dynamic physiological behavior

Projection-Based Clustering through Self-Organization and Swarm Intelligence: Combining Cluster Analysis with the Visualization of High-Dimensional Data

Cluster Analysis; Dimensionality Reduction; Swarm Intelligence; Visualization; Unsupervised Machine Learning; Data Science; Knowledge Discovery; 3D Printing; Self-Organization; Emergence; Game Theory; Advanced Analytics; High-Dimensional Data; Multivariate Data; Analysis of Structured Dat