40,602 research outputs found

    Complete LibTech 2013 Print Program

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    PDF of the complete print program from the 2013 Library Technology Conferenc

    Immunochromatographic diagnostic test analysis using Google Glass.

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    We demonstrate a Google Glass-based rapid diagnostic test (RDT) reader platform capable of qualitative and quantitative measurements of various lateral flow immunochromatographic assays and similar biomedical diagnostics tests. Using a custom-written Glass application and without any external hardware attachments, one or more RDTs labeled with Quick Response (QR) code identifiers are simultaneously imaged using the built-in camera of the Google Glass that is based on a hands-free and voice-controlled interface and digitally transmitted to a server for digital processing. The acquired JPEG images are automatically processed to locate all the RDTs and, for each RDT, to produce a quantitative diagnostic result, which is returned to the Google Glass (i.e., the user) and also stored on a central server along with the RDT image, QR code, and other related information (e.g., demographic data). The same server also provides a dynamic spatiotemporal map and real-time statistics for uploaded RDT results accessible through Internet browsers. We tested this Google Glass-based diagnostic platform using qualitative (i.e., yes/no) human immunodeficiency virus (HIV) and quantitative prostate-specific antigen (PSA) tests. For the quantitative RDTs, we measured activated tests at various concentrations ranging from 0 to 200 ng/mL for free and total PSA. This wearable RDT reader platform running on Google Glass combines a hands-free sensing and image capture interface with powerful servers running our custom image processing codes, and it can be quite useful for real-time spatiotemporal tracking of various diseases and personal medical conditions, providing a valuable tool for epidemiology and mobile health

    UEFI BIOS Accessibility for the Visually Impaired

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    People with some kind of disability face a high level of difficulty for everyday tasks because, in many cases, accessibility was not considered necessary when the task or process was designed. An example of this scenario is a computer's BIOS configuration screens, which do not consider the specific needs, such as screen readers, of visually impaired people. This paper proposes the idea that it is possible to make the pre-operating system environment accessible to visually impaired people. We report our work-in-progress in creating a screen reader prototype, accessing audio cards compatible with the High Definition Audio specification in systems running UEFI compliant firmware.Comment: 6 page

    Actor-network procedures: Modeling multi-factor authentication, device pairing, social interactions

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    As computation spreads from computers to networks of computers, and migrates into cyberspace, it ceases to be globally programmable, but it remains programmable indirectly: network computations cannot be controlled, but they can be steered by local constraints on network nodes. The tasks of "programming" global behaviors through local constraints belong to the area of security. The "program particles" that assure that a system of local interactions leads towards some desired global goals are called security protocols. As computation spreads beyond cyberspace, into physical and social spaces, new security tasks and problems arise. As networks are extended by physical sensors and controllers, including the humans, and interlaced with social networks, the engineering concepts and techniques of computer security blend with the social processes of security. These new connectors for computational and social software require a new "discipline of programming" of global behaviors through local constraints. Since the new discipline seems to be emerging from a combination of established models of security protocols with older methods of procedural programming, we use the name procedures for these new connectors, that generalize protocols. In the present paper we propose actor-networks as a formal model of computation in heterogenous networks of computers, humans and their devices; and we introduce Procedure Derivation Logic (PDL) as a framework for reasoning about security in actor-networks. On the way, we survey the guiding ideas of Protocol Derivation Logic (also PDL) that evolved through our work in security in last 10 years. Both formalisms are geared towards graphic reasoning and tool support. We illustrate their workings by analysing a popular form of two-factor authentication, and a multi-channel device pairing procedure, devised for this occasion.Comment: 32 pages, 12 figures, 3 tables; journal submission; extended references, added discussio

    Beyond representations: towards an action-centric perspective on tangible interaction

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    In the light of theoretical as well as concrete technical development, we discuss a conceptual shift from an information-centric to an action-centric perspective on tangible interactive technology. We explicitly emphasise the qualities of shareable use, and the importance of designing tangibles that allow for meaningful manipulation and control of the digital material. This involves a broadened focus from studying properties of the interface, to instead aim for qualities of the activity of using a system, a general tendency towards designing for social and sharable use settings and an increased openness towards multiple and subjective interpretations. An effect of this is that tangibles are not designed as representations of data, but as resources for action. We discuss four ways that tangible artefacts work as resources for action: (1) for physical manipulation; (2) for referential, social and contextually oriented action; (3) for perception and sensory experience; (4) for digitally mediated action

    Single cell analysis of neutrophils NETs by Microscopic LSPR imaging system

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    A simple microengraving cell monitoring method for neutrophil extracellular traps (NETs) released from single neutrophils has been realized using a polydimethylsiloxane (PDMS) microwell array (MWA) sheet on a plasmon chip platform. An imbalance between NETs formation and the succeeding degradation (NETosis) are considered associated with autoimmune disease and its pathogenesis. Thus, an alternative platform that can conduct monitoring of this activity on single cell level at minimum cost but with great sensitivity is greatly desired. The developed MWA plasmon chips allow single cell isolation of neutrophils from 150 μL suspension (6.0 × 105 cells/mL) with an efficiency of 36.3%; 105 microwells with single cell condition. To demonstrate the utility of the chip, trapped cells were incubated between 2 to 4 h after introducing with 100 nM phorbol 12- myristate 13-acetate (PMA) before measurement. Under observation using a hyperspectral imaging system that allows high-throughput screening, the neutrophils stimulated by PMA solution show a significant release of fibrils and NETs after 4 h, with observed maximum areas between 314–758 μm2. An average absorption peak wavelength shows a redshift of Δλ = 1.5 nm as neutrophils release NETs
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