Wireless body sensor networks for health-monitoring applications

This is an author-created, un-copyedited version of an article accepted for publication in Physiological Measurement. The publisher is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at http://dx.doi.org/10.1088/0967-3334/29/11/R01

Design of a Customized multipurpose nano-enabled implantable system for in-vivo theranostics

The first part of this paper reviews the current development and key issues on implantable multi-sensor devices for in vivo theranostics. Afterwards, the authors propose an innovative biomedical multisensory system for in vivo biomarker monitoring that could be suitable for customized theranostics applications. At this point, findings suggest that cross-cutting Key Enabling Technologies (KETs) could improve the overall performance of the system given that the convergence of technologies in nanotechnology, biotechnology, micro&nanoelectronics and advanced materials permit the development of new medical devices of small dimensions, using biocompatible materials, and embedding reliable and targeted biosensors, high speed data communication, and even energy autonomy. Therefore, this article deals with new research and market challenges of implantable sensor devices, from the point of view of the pervasive system, and time-to-market. The remote clinical monitoring approach introduced in this paper could be based on an array of biosensors to extract information from the patient. A key contribution of the authors is that the general architecture introduced in this paper would require minor modifications for the final customized bio-implantable medical device

Future of smart cardiovascular implants

Cardiovascular disease remains the leading cause of death in Western society. Recent technological advances have opened the opportunity of developing new and innovative smart stent devices that have advanced electrical properties that can improve diagnosis and even treatment of previously intractable conditions, such as central line access failure, atherosclerosis and reporting on vascular grafts for renal dialysis. Here we review the latest advances in the field of cardiovascular medical implants, providing a broad overview of the application of their use in the context of cardiovascular disease rather than an in-depth analysis of the current state of the art. We cover their powering, communication and the challenges faced in their fabrication. We focus specifically on those devices required to maintain vascular access such as ones used to treat arterial disease, a major source of heart attacks and strokes. We look forward to advances in these technologies in the future and their implementation to improve the human condition

Platform Development for the Implementation and Testing of New Swarming Strategies

Gemstone Team SWARM-AISwarm robotics--the use of multiple autonomous robots in coordination to accomplish a task--is useful for mapping, light package transport, and search and rescue operations, among other applications. Researchers and industry professionals have developed robotic swarm mechanisms to accomplish these tasks. Some of those mechanisms or “strategies” have been tested on hardware; however, the technical requirements involved in fielding a drone swarm can be prohibitive to physical testing. Team SWARM-AI has developed a platform that provides a starting point for testing new swarming strategies. This platform allows the user to select vehicles of their choosing- either air, land, or water based, or some combination thereof- as well as define their own swarming method. Using a novel decentralized approach to ground control software, this platform provides a user interface and a system of computational “units” to coordinate drone swarms with a centralized, decentralized, or combination architecture. Additionally, the platform propagates user input from the master unit to the rest of the swarm and allows each unit to request sensor data from other units. The user is free to edit the processes by which each drone interacts with the environment and the rest of the swarm, giving them freedom to test their swarming strategy. The software system is then tested with a swarm of quadcopters using Software in the Loop (SITL) testing

A compact targeted drug delivery mechanism for a next generation wireless capsule endoscope

This paper reports a novel medication release and delivery mechanism as part of a next generation wireless capsule endoscope (WCE) for targeted drug delivery. This subsystem occupies a volume of only 17.9mm3 for the purpose of delivering a 1 ml payload to a target site of interest in the small intestinal tract. An in-depth analysis of the method employed to release and deliver the medication is described and a series of experiments is presented which validates the drug delivery system. The results show that a variable pitch conical compression spring manufactured from stainless steel can deliver 0.59 N when it is fully compressed and that this would be sufficient force to deliver the onboard medication

Formation coordination and network management of UAV networks using particle swarm optimization and software-defined networking

In recent years, with the growth in the use of Unmanned Aerial Vehicles (UAVs), UAV-based systems have become popular in both military and civil applications. The lack of reliable communication infrastructure in these scenarios has motivated the use of UAVs to establish a network as flying nodes, also known as UAV networks. However, the high mobility degree of flying and terrestrial users may be responsible for constant changes in nodes’ positioning, which makes it more challenging to guarantee their communication during the operational time. In this context, this work presents a framework solution for formation coordination and network management of UAVs, which aims to establish and maintain a set of relays units in order to provide a constant, reliable and efficient communication link among user nodes - which are performing individual or collaborative missions on its turn. Such a framework relies on a set of formation coordination algorithms - including the Particle Swarm Optimization (PSO) evolutionary algorithm -, and also considers the use of Software-defined Networking-based (SDN) communication protocol for network management. For coordination proposes, a novel particle selection criteria is proposed, which aims to guarantee network manageability of UAV formations, therefore being able to guarantee service persistence in case of nodes’ failure occurrence, as well as to provide required network performance, as a consequence. Simulations performed in OMNeT++ show the efficiency of the proposed solution and prove a promising direction of the solution for accomplishing its purposes.Em regiões de confrontos militares, em cenários pós-catástrofes naturais e, inclusive, em grandes áreas de cultivo agrícola, é comum a ausência de uma infra-estrutura préestabelecida de comunicação entre usuários durante a execução de uma ou mais operações eventuais. Nestes casos, Veículos Aéreos Não Tripulados (VANTs) podem ser vistos como uma alternativa para o estabelecimento de uma rede temporária durante essas missões. Para algumas aplicações, a alta mobilidade destes usuários podem trazem grandes desafios para o gerenciamento autônomo de uma estrutura de comunicação aérea, como a organização espacial dos nós roteadores e as políticas de encaminhamento de pacotes adotadas durante a operação. Tendo isso em vista, esse trabalho apresenta o estudo de uma solução que visa o estabelecimento e manutenção das conexões entre os usuários - nos quais executam tarefas individuais ou colaborativas -, através do uso de algoritmos de coordenação de formação - no qual inclui o algoritmo evolucionário Otimização por Enxame de Partículas -, e, também, de conceitos relacionados a Rede Definidas por Software para o gerenciamento da rede. Ainda, é proposto um novo critério de seleção das partículas do algoritmo evolucionário, visando garantir gerenciabilidade das topologias formadas e, consequentemente, a persistência do serviço em caso de falha dos nós roteadores, assim como o cumprimento de especificações desejadas para o desempenho da rede. Simulações em OMNeT++ mostraram a eficácia da proposta e sustentam o modelo proposto a fim de atingir seus objetivos

Fully Integrated Biochip Platforms for Advanced Healthcare

Recent advances in microelectronics and biosensors are enabling developments of innovative biochips for advanced healthcare by providing fully integrated platforms for continuous monitoring of a large set of human disease biomarkers. Continuous monitoring of several human metabolites can be addressed by using fully integrated and minimally invasive devices located in the sub-cutis, typically in the peritoneal region. This extends the techniques of continuous monitoring of glucose currently being pursued with diabetic patients. However, several issues have to be considered in order to succeed in developing fully integrated and minimally invasive implantable devices. These innovative devices require a high-degree of integration, minimal invasive surgery, long-term biocompatibility, security and privacy in data transmission, high reliability, high reproducibility, high specificity, low detection limit and high sensitivity. Recent advances in the field have already proposed possible solutions for several of these issues. The aim of the present paper is to present a broad spectrum of recent results and to propose future directions of development in order to obtain fully implantable systems for the continuous monitoring of the human metabolism in advanced healthcare applications