Detection of Inferior Myocardial Infarction using Shallow Convolutional Neural Networks

Myocardial Infarction is one of the leading causes of death worldwide. This paper presents a Convolutional Neural Network (CNN) architecture which takes raw Electrocardiography (ECG) signal from lead II, III and AVF and differentiates between inferior myocardial infarction (IMI) and healthy signals. The performance of the model is evaluated on IMI and healthy signals obtained from Physikalisch-Technische Bundesanstalt (PTB) database. A subject-oriented approach is taken to comprehend the generalization capability of the model and compared with the current state of the art. In a subject-oriented approach, the network is tested on one patient and trained on rest of the patients. Our model achieved a superior metrics scores (accuracy= 84.54%, sensitivity= 85.33% and specificity= 84.09%) when compared to the benchmark. We also analyzed the discriminating strength of the features extracted by the convolutional layers by means of geometric separability index and euclidean distance and compared it with the benchmark model

Automated ECG Analysis for Localizing Thrombus in Culprit Artery Using Rule Based Information Fuzzy Network

Cardio-vascular diseases are one of the foremost causes of mortality in today’s world. The prognosis for cardiovascular diseases is usually done by ECG signal, which is a simple 12-lead Electrocardiogram (ECG) that gives complete information about the function of the heart including the amplitude and time interval of P-QRST-U segment. This article recommends a novel approach to identify the location of thrombus in culprit artery using the Information Fuzzy Network (IFN). Information Fuzzy Network, being a supervised machine learning technique, takes known evidences based on rules to create a predicted classification model with thrombus location obtained from the vast input ECG data. These rules are well-defined procedures for selecting hypothesis that best fits a set of observations. Results illustrate that the recommended approach yields an accurateness of 92.30%. This novel approach is shown to be a viable ECG analysis approach for identifying the culprit artery and thus localizing the thrombus

Application of artificial intelligence techniques for automated detection of myocardial infarction: A review

Myocardial infarction (MI) results in heart muscle injury due to receiving insufficient blood flow. MI is the most common cause of mortality in middle-aged and elderly individuals around the world. To diagnose MI, clinicians need to interpret electrocardiography (ECG) signals, which requires expertise and is subject to observer bias. Artificial intelligence-based methods can be utilized to screen for or diagnose MI automatically using ECG signals. In this work, we conducted a comprehensive assessment of artificial intelligence-based approaches for MI detection based on ECG as well as other biophysical signals, including machine learning (ML) and deep learning (DL) models. The performance of traditional ML methods relies on handcrafted features and manual selection of ECG signals, whereas DL models can automate these tasks. The review observed that deep convolutional neural networks (DCNNs) yielded excellent classification performance for MI diagnosis, which explains why they have become prevalent in recent years. To our knowledge, this is the first comprehensive survey of artificial intelligence techniques employed for MI diagnosis using ECG and other biophysical signals.Comment: 16 pages, 8 figure

Toward Automated Feature Extraction for Deep Learning Classification of Electrocardiogram Signals

Many recent studies have focused on the automatic classification of electrocardiogram (ECG) signals using deep learning (DL) methods. Most rely on existing complex DL methods, such as transfer learning or providing the models with carefully designed extracted features based on domain knowledge. A common assumption is that the deeper and more complex the DL model is, the better it learns. In this study, we propose two different DL models for automatic feature extraction from ECG signals for classification tasks: A CNN-LSTM hybrid model and an attention/transformer-based model with wavelet transform for the dimensional embedding. Both of the models extract the features from time series at the initial layers of the neural networks and can obtain performance at least equal to, if not greater than, many contemporary deep neural networks. To validate our hypothesis, we used three publicly available data-sets to evaluate the proposed models. Our model achieved a benchmark accuracy of 99.92% for fall detection and 99.93% for the PTB database for myocardial infarction versus normal heartbeat classification

Detection of Myocardial Infarction using ECG and Multi-Scale Feature Concatenate

Diverse computer-aided diagnosis systems based on convolutional neural networks were applied to automate the detection of myocardial infarction (MI) found in electrocardiogram (ECG) for early diagnosis and prevention. However; issues; particularly overfitting and underfitting; were not being taken into account. In other words; it is unclear whether the network structure is too simple or complex. Toward this end; the proposed models were developed by starting with the simplest structure: a multi-lead features-concatenate narrow network (N-Net) in which only two convolutional layers were included in each lead branch. Additionally; multi-scale features-concatenate networks (MSN-Net) were also implemented where larger features were being extracted through pooling the signals. The best structure was obtained via tuning both the number of filters in the convolutional layers and the number of inputting signal scales. As a result; the N-Net reached a 95.76% accuracy in the MI detection task; whereas the MSN-Net reached an accuracy of 61.82% in the MI locating task. Both networks give a higher average accuracy and a significant difference of p \u3c 0.001 evaluated by the U test compared with the state-of-the-art. The models are also smaller in size thus are suitable to fit in wearable devices for offline monitoring. In conclusion; testing throughout the simple and complex network structure is indispensable. However; the way of dealing with the class imbalance problem and the quality of the extracted features are yet to be discussed

Analysis of Ventricular Depolarisation and Repolarisation Using Registration and Machine Learning

Our understanding of cardiac diseases has greatly advanced since the advent of electrocardiography (ECG). With the increasing influx of available data in recent times, significant research efforts have been put forth to automate the study and detection of cardiac conditions. Naturally, the focus has progressed toward studying dynamic changes in ventricular depolarisation and repolarisation across serial recordings - as complex beat-to-beat changes in morphology manifest over time. Manual extraction of diagnostic and prognostic markers is a laborious task. Hence, automated and accurate methods are required to extract markers for the study of ventricular lability and detection of common diseases, such as myocardial ischemia and myocardial infarction. The aim of this thesis is to improve automated marker extraction and detection of diseases for the study of ventricular depolarisation and repolarisation lability in ECG. As such, two novel template adaptation methods capable of capturing complex beat-to-beat morphological changes are proposed for three-dimensional and two-dimensional data, respectively. The proposed three-dimensional template adaptation method provides an inhomogeneous method for transforming template vectorcardiogram (VCG) by exploiting registrationinspired parametrisation and an efficient kernel ridge regression formulation. Analysis across simulated data and clinical myocardial infarction data demonstrates state-of-the-art results. The two-dimensional template adaptation method draws from traditional registrationbased techniques and treats the ECG as a two-dimensional point set problem. Validation against previously employed simulated data and a gold-standard annotated clinical database demonstrate the highest level of performance. Subsequently, frameworks employing the proposed template adaptation techniques are developed for the automated detection of ischemic beats and myocardial infarction. Furthermore, a small study analysing ventricular repolarisation variability (VRV) in non-ischemic cardiomyopathy (CM) is considered, utilising markers of cardiac lability proposed in the development of the three-dimensional template adaptation system. In summary, this thesis highlights the necessity for custom template adaptation methods for the accurate measurement of beat-to-beat variability in cardiac data. Two novel stateof- the-art methods are proposed and extended to study myocardial ischemia, myocardial infarction and non-ischemic CM.Thesis (Ph.D.) -- University of Adelaide, School of Electrical and Electronic Engineering, 202

Comprehensive electrocardiographic diagnosis based on deep learning

Cardiovascular disease (CVD) is the leading cause of death worldwide, and coronary artery disease (CAD) is a major contributor. Early-stage CAD can progress if undiagnosed and left untreated, leading to myocardial infarction (MI) that may induce irreversible heart muscle damage, resulting in heart chamber remodeling and eventual congestive heart failure (CHF). Electrocardiography (ECG) signals can be useful to detect established MI, and may also be helpful for early diagnosis of CAD. For the latter especially, the ECG perturbations can be subtle and potentially misclassified on manual interpretation and/or when analyzed by traditional algorithms found in ECG instrumentation. For automated diagnostic systems (ADS), deep learning techniques are favored over conventional machine learning techniques, due to the automatic feature extraction and selection processes involved. This paper highlights various deep learning algorithms exploited for the classification of ECG signals into CAD, MI, and CHF conditions. The Convolutional Neural Network (CNN), followed by combined CNN and Long Short-Term Memory (LSTM) models, appear to be the most useful architectures for classification. A 16-layer LSTM model was developed in our study and validated using 10-fold cross validation. A classification accuracy of 98.5% was achieved. Our proposed model has the potential to be a useful diagnostic tool in hospitals for the classification of abnormal ECG signals

Detection of myocardial infarction based on novel deep transfer learning methods for urban healthcare in smart cities

YesOne of the common cardiac disorders is a cardiac attack called Myocardial infarction (MI), which occurs due to the blockage of one or more coronary arteries. Timely treatment of MI is important and slight delay results in severe consequences. Electrocardiogram (ECG) is the main diagnostic tool to monitor and reveal the MI signals. The complex nature of MI signals along with noise poses challenges to doctors for accurate and quick diagnosis. Manually studying large amounts of ECG data can be tedious and time-consuming. Therefore, there is a need for methods to automatically analyze the ECG data and make diagnosis. Number of studies has been presented to address MI detection, but most of these methods are computationally expensive and faces the problem of overfitting while dealing real data. In this paper, an effective computer-aided diagnosis (CAD) system is presented to detect MI signals using the convolution neural network (CNN) for urban healthcare in smart cities. Two types of transfer learning techniques are employed to retrain the pre-trained VGG-Net (Fine-tuning and VGG-Net as fixed feature extractor) and obtained two new networks VGG-MI1 and VGG-MI2. In the VGG-MI1 model, the last layer of the VGG-Net model is replaced with a specific layer according to our requirements and various functions are optimized to reduce overfitting. In the VGG-MI2 model, one layer of the VGG-Net model is selected as a feature descriptor of the ECG images to describe it with informative features. Considering the limited availability of dataset, ECG data is augmented which has increased the classification performance. A standard well-known database Physikalisch-Technische Bundesanstalt (PTB) Diagnostic ECG is used for the validation of the proposed framework. It is evident from experimental results that the proposed framework achieves a high accuracy surpasses the existing methods. In terms of accuracy, sensitivity, and specificity; VGG-MI1 achieved 99.02%, 98.76%, and 99.17%, respectively, while VGG-MI2 models achieved an accuracy of 99.22%, a sensitivity of 99.15%, and a specificity of 99.49%.This project was funded by University of Jeddah, Jeddah, Saudi Arabia (Project number: UJ-02-018-ICGR)