4 research outputs found
A Queer Politics of Imperceptibility: A Philosophy of Resistance to Contemporary Sexual Surveillance
This thesis journeys through a series of events to develop a concept of “imperceptibility” as a mode of resistance to contemporary sexual surveillance. The events I examine include biometric recognition of gender and race at airport security checkpoints, the heteropatriarchal colonial surveillance of Indigenous peoples at Standing Rock, various protest actions, and the political potentials of glitch art. Exploring their unexpected points of connection, my goal is to bring into view acts of resistance against sexual surveillance that already operate below and above the threshold of everyday perception.
The project advocates for a philosophy of resistance that underscores the political importance of creating new modes of existence. Rather than engaging in the problematic of devising a new model of subjectivity, I argue that what is needed to escape from contemporary systems of capture and control is to turn from the Self as the primary site of concern and affirm instead the potentials of becoming-imperceptible. Imperceptibility signals not invisibility, but the act of relinquishing identity in favour of moving toward becoming everybody/everything. Far from a homogenizing or unitary endeavour, I propose imperceptibility as a radical celebration of difference that surges a revolutionary desire for social transformation through interconnectedness.
Activating Gilles Deleuze and Félix Guattari’s pragmatic philosophy and style of writing, which emphasize multiple relations over binary oppositions, I introduce “a queer politics of imperceptibility” as a conceptual framework that takes a both/and approach to consider resistance. That is, I work with and between the tensions of feminist theories of recognition and Deleuze and Guattari’s nonrepresentational philosophy. I develop this framework in each chapter by mapping a constellation of interacting forces and affective intensities between bodies, both human and non-human. A Queer Politics of Imperceptibility makes an important intervention into the fields of feminist surveillance studies, posthumanism, affect theory, postcolonial theory and queer theory by revealing the ways in which imperceptible relations of resistance cascade into the political to generate new potentials to act in the world
Европейский и национальный контексты в научных исследованиях
В настоящем электронном сборнике «Европейский и национальный контексты в научных исследованиях. Технология» представлены работы молодых ученых по геодезии и картографии, химической технологии и машиностроению, информационным технологиям, строительству и радиотехнике. Предназначены для работников образования, науки и производства. Будут полезны студентам, магистрантам и аспирантам университетов.=In this Electronic collected materials “National and European dimension in research. Technology” works in the fields of geodesy, chemical technology, mechanical engineering, information technology, civil engineering, and radio-engineering are presented. It is intended for trainers, researchers and professionals. It can be useful for university graduate and post-graduate students
Ultrasensitive detection of toxocara canis excretory-secretory antigens by a nanobody electrochemical magnetosensor assay.
peer reviewedHuman Toxocariasis (HT) is a zoonotic disease caused by the migration
of the larval stage of the roundworm Toxocara canis in the human host.
Despite of being the most cosmopolitan helminthiasis worldwide, its
diagnosis is elusive. Currently, the detection of specific immunoglobulins
IgG against the Toxocara Excretory-Secretory Antigens (TES), combined
with clinical and epidemiological criteria is the only strategy to diagnose
HT. Cross-reactivity with other parasites and the inability to distinguish
between past and active infections are the main limitations of this
approach. Here, we present a sensitive and specific novel strategy to
detect and quantify TES, aiming to identify active cases of HT. High
specificity is achieved by making use of nanobodies (Nbs), recombinant
single variable domain antibodies obtained from camelids, that due to
their small molecular size (15kDa) can recognize hidden epitopes not
accessible to conventional antibodies. High sensitivity is attained by the
design of an electrochemical magnetosensor with an amperometric readout
with all components of the assay mixed in one single step. Through
this strategy, 10-fold higher sensitivity than a conventional sandwich
ELISA was achieved. The assay reached a limit of detection of 2 and15
pg/ml in PBST20 0.05% or serum, spiked with TES, respectively. These
limits of detection are sufficient to detect clinically relevant toxocaral
infections. Furthermore, our nanobodies showed no cross-reactivity
with antigens from Ascaris lumbricoides or Ascaris suum. This is to our
knowledge, the most sensitive method to detect and quantify TES so far,
and has great potential to significantly improve diagnosis of HT. Moreover,
the characteristics of our electrochemical assay are promising for the
development of point of care diagnostic systems using nanobodies as a
versatile and innovative alternative to antibodies. The next step will be the
validation of the assay in clinical and epidemiological contexts