Automatic landmark annotation and dense correspondence registration for 3D human facial images

Dense surface registration of three-dimensional (3D) human facial images holds great potential for studies of human trait diversity, disease genetics, and forensics. Non-rigid registration is particularly useful for establishing dense anatomical correspondences between faces. Here we describe a novel non-rigid registration method for fully automatic 3D facial image mapping. This method comprises two steps: first, seventeen facial landmarks are automatically annotated, mainly via PCA-based feature recognition following 3D-to-2D data transformation. Second, an efficient thin-plate spline (TPS) protocol is used to establish the dense anatomical correspondence between facial images, under the guidance of the predefined landmarks. We demonstrate that this method is robust and highly accurate, even for different ethnicities. The average face is calculated for individuals of Han Chinese and Uyghur origins. While fully automatic and computationally efficient, this method enables high-throughput analysis of human facial feature variation.Comment: 33 pages, 6 figures, 1 tabl

Automated System for Early Breast Cancer Detection in Mammograms

The increasing demand on mammographic screening for early breast cancer detection, and the subtlety of early breast cancer signs on mammograms, suggest an automated image processing system that can serve as a diagnostic aid in radiology clinics. We present a fully automated algorithm for detecting clusters of microcalcifications that are the most common signs of early, potentially curable breast cancer. By using the contour map of the mammogram, the algorithm circumvents some of the difficulties encountered with standard image processing methods. The clinical implementation of an automated instrument based on this algorithm is also discussed

Voicing classification of visual speech using convolutional neural networks

The application of neural network and convolutional neural net- work (CNN) architectures is explored for the tasks of voicing classification (classifying frames as being either non-speech, unvoiced, or voiced) and voice activity detection (VAD) of vi- sual speech. Experiments are conducted for both speaker de- pendent and speaker independent scenarios. A Gaussian mixture model (GMM) baseline system is de- veloped using standard image-based two-dimensional discrete cosine transform (2D-DCT) visual speech features, achieving speaker dependent accuracies of 79% and 94%, for voicing classification and VAD respectively. Additionally, a single- layer neural network system trained using the same visual fea- tures achieves accuracies of 86 % and 97 %. A novel technique using convolutional neural networks for visual speech feature extraction and classification is presented. The voicing classifi- cation and VAD results using the system are further improved to 88 % and 98 % respectively. The speaker independent results show the neural network system to outperform both the GMM and CNN systems, achiev- ing accuracies of 63 % for voicing classification, and 79 % for voice activity detection