Spectral imaging in preclinical research and clinical pathology.

Spectral imaging methods are attracting increased interest from researchers and practitioners in basic science, pre-clinical and clinical arenas. A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular level. These tools can provide valuable insights into the basic mechanisms of life, and yield diagnostic and prognostic information for clinical applications. There are many multispectral technologies available, each with its own advantages and limitations. This chapter will present an overview of the rationale for spectral imaging, and discuss the hardware, software and sample labeling strategies that can optimize its usefulness in clinical settings

Multispectral Palmprint Encoding and Recognition

Palmprints are emerging as a new entity in multi-modal biometrics for human identification and verification. Multispectral palmprint images captured in the visible and infrared spectrum not only contain the wrinkles and ridge structure of a palm, but also the underlying pattern of veins; making them a highly discriminating biometric identifier. In this paper, we propose a feature encoding scheme for robust and highly accurate representation and matching of multispectral palmprints. To facilitate compact storage of the feature, we design a binary hash table structure that allows for efficient matching in large databases. Comprehensive experiments for both identification and verification scenarios are performed on two public datasets -- one captured with a contact-based sensor (PolyU dataset), and the other with a contact-free sensor (CASIA dataset). Recognition results in various experimental setups show that the proposed method consistently outperforms existing state-of-the-art methods. Error rates achieved by our method (0.003% on PolyU and 0.2% on CASIA) are the lowest reported in literature on both dataset and clearly indicate the viability of palmprint as a reliable and promising biometric. All source codes are publicly available.Comment: Preliminary version of this manuscript was published in ICCV 2011. Z. Khan A. Mian and Y. Hu, "Contour Code: Robust and Efficient Multispectral Palmprint Encoding for Human Recognition", International Conference on Computer Vision, 2011. MATLAB Code available: https://sites.google.com/site/zohaibnet/Home/code

Infrared face recognition: a comprehensive review of methodologies and databases

Automatic face recognition is an area with immense practical potential which includes a wide range of commercial and law enforcement applications. Hence it is unsurprising that it continues to be one of the most active research areas of computer vision. Even after over three decades of intense research, the state-of-the-art in face recognition continues to improve, benefitting from advances in a range of different research fields such as image processing, pattern recognition, computer graphics, and physiology. Systems based on visible spectrum images, the most researched face recognition modality, have reached a significant level of maturity with some practical success. However, they continue to face challenges in the presence of illumination, pose and expression changes, as well as facial disguises, all of which can significantly decrease recognition accuracy. Amongst various approaches which have been proposed in an attempt to overcome these limitations, the use of infrared (IR) imaging has emerged as a particularly promising research direction. This paper presents a comprehensive and timely review of the literature on this subject. Our key contributions are: (i) a summary of the inherent properties of infrared imaging which makes this modality promising in the context of face recognition, (ii) a systematic review of the most influential approaches, with a focus on emerging common trends as well as key differences between alternative methodologies, (iii) a description of the main databases of infrared facial images available to the researcher, and lastly (iv) a discussion of the most promising avenues for future research.Comment: Pattern Recognition, 2014. arXiv admin note: substantial text overlap with arXiv:1306.160

Biometric presentation attack detection: beyond the visible spectrum

The increased need for unattended authentication in multiple scenarios has motivated a wide deployment of biometric systems in the last few years. This has in turn led to the disclosure of security concerns specifically related to biometric systems. Among them, presentation attacks (PAs, i.e., attempts to log into the system with a fake biometric characteristic or presentation attack instrument) pose a severe threat to the security of the system: any person could eventually fabricate or order a gummy finger or face mask to impersonate someone else. In this context, we present a novel fingerprint presentation attack detection (PAD) scheme based on i) a new capture device able to acquire images within the short wave infrared (SWIR) spectrum, and i i) an in-depth analysis of several state-of-theart techniques based on both handcrafted and deep learning features. The approach is evaluated on a database comprising over 4700 samples, stemming from 562 different subjects and 35 different presentation attack instrument (PAI) species. The results show the soundness of the proposed approach with a detection equal error rate (D-EER) as low as 1.35% even in a realistic scenario where five different PAI species are considered only for testing purposes (i.e., unknown attacks

Uncertainty-Aware Organ Classification for Surgical Data Science Applications in Laparoscopy

Objective: Surgical data science is evolving into a research field that aims to observe everything occurring within and around the treatment process to provide situation-aware data-driven assistance. In the context of endoscopic video analysis, the accurate classification of organs in the field of view of the camera proffers a technical challenge. Herein, we propose a new approach to anatomical structure classification and image tagging that features an intrinsic measure of confidence to estimate its own performance with high reliability and which can be applied to both RGB and multispectral imaging (MI) data. Methods: Organ recognition is performed using a superpixel classification strategy based on textural and reflectance information. Classification confidence is estimated by analyzing the dispersion of class probabilities. Assessment of the proposed technology is performed through a comprehensive in vivo study with seven pigs. Results: When applied to image tagging, mean accuracy in our experiments increased from 65% (RGB) and 80% (MI) to 90% (RGB) and 96% (MI) with the confidence measure. Conclusion: Results showed that the confidence measure had a significant influence on the classification accuracy, and MI data are better suited for anatomical structure labeling than RGB data. Significance: This work significantly enhances the state of art in automatic labeling of endoscopic videos by introducing the use of the confidence metric, and by being the first study to use MI data for in vivo laparoscopic tissue classification. The data of our experiments will be released as the first in vivo MI dataset upon publication of this paper.Comment: 7 pages, 6 images, 2 table

Histopathological image analysis : a review

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe