149,842 research outputs found

    Disinvestment in healthcare: An overview of HTA agencies and organizations activities at European level

    Get PDF
    Background: In an era of a growing economic pressure for all health systems, the interest for "disinvestment" in healthcare increased. In this context, evidence based approaches such as Health Technology Assessment (HTA) are needed both to invest and to disinvest in health technologies. In order to investigate the extent of application of HTA in this field, methodological projects/frameworks, case studies, dissemination initiatives on disinvestment released by HTA agencies and organizations located in Europe were searched. Methods: In July 2015, the websites of HTA agencies and organizations belonging to the European network for HTA (EUnetHTA) and the International Network of Agencies for HTA (INAHTA) were accessed and searched through the use of the term "disinvestment". Retrieved deliverables were considered eligible if they reported methodological projects/frameworks, case studies and dissemination initiatives focused on disinvestment in healthcare. Results: 62 HTA agencies/organizations were accessed and eight methodological projects/frameworks, one case study and one dissemination initiative were found starting from 2007. With respect to methodological projects/frameworks, two were delivered in Austria, one in Italy, two in Spain and three in U.K. As for the case study and the dissemination initiative, both came from U.K. The majority of deliverables were aimed at making an overview of existing disinvestment approaches and at identifying challenges in their introduction. Conclusions: Today, in a healthcare context characterized by resource scarcity and increasing service demand, "disinvestment" from low-value services and reinvestment in high-value ones is a key strategy that may be supported by HTA. The lack of evaluation of technologies in use, in particular at the end of their lifecycle, may be due to the scant availability of frameworks and guidelines for identification and assessment of obsolete technologies that was shown by our work. Although several projects were carried out in different countries, most remain constrained to the field of research. Disinvestment is a relatively new concept in HTA that could pose challenges also from a methodological point of view. To tackle these challenges, it is necessary to construct experiences at international level with the aim to develop new methodological approaches to produce and grow evidence on disinvestment policies and practices

    Ontology population for open-source intelligence: A GATE-based solution

    Get PDF
    Open-Source INTelligence is intelligence based on publicly available sources such as news sites, blogs, forums, etc. The Web is the primary source of information, but once data are crawled, they need to be interpreted and structured. Ontologies may play a crucial role in this process, but because of the vast amount of documents available, automatic mechanisms for their population are needed, starting from the crawled text. This paper presents an approach for the automatic population of predefined ontologies with data extracted from text and discusses the design and realization of a pipeline based on the General Architecture for Text Engineering system, which is interesting for both researchers and practitioners in the field. Some experimental results that are encouraging in terms of extracted correct instances of the ontology are also reported. Furthermore, the paper also describes an alternative approach and provides additional experiments for one of the phases of our pipeline, which requires the use of predefined dictionaries for relevant entities. Through such a variant, the manual workload required in this phase was reduced, still obtaining promising results

    Transient loads analysis for space flight applications

    Get PDF
    A significant part of the flight readiness verification process involves transient analysis of the coupled Shuttle-payload system to determine the low frequency transient loads. This paper describes a methodology for transient loads analysis and its implementation for the Spacelab Life Sciences Mission. The analysis is carried out using two major software tools - NASTRAN and an external FORTRAN code called EZTRAN. This approach is adopted to overcome some of the limitations of NASTRAN's standard transient analysis capabilities. The method uses Data Recovery Matrices (DRM) to improve computational efficiency. The mode acceleration method is fully implemented in the DRM formulation to recover accurate displacements, stresses, and forces. The advantages of the method are demonstrated through a numerical example

    Integrating case study and survey research methods: An example in information systems

    Get PDF
    The case for combining research methods generally, and more specifically that for combining qualitative and quantitative methods, is strong. Yet, research designs that extensively integrate both fieldwork (e.g. case studies) and survey research are rare. More¬over, some journals tend tacitly to specialize by methodology thereby encouraging purity of method. The multi-method model of research while not new, has not been appreciated. In this respect it is useful to articulate and describe its usage through example. By reference to a recently completed study of IS consultant engagement success factors this paper presents an analysis of the benefits of integrating case study and survey research methods. The emphasis is on the qualitative case study method and how it can compliment more quantitative survey research. Benefits are demonstrated through specific examples from the reference study.</i

    Mining Knowledge in Astrophysical Massive Data Sets

    Full text link
    Modern scientific data mainly consist of huge datasets gathered by a very large number of techniques and stored in very diversified and often incompatible data repositories. More in general, in the e-science environment, it is considered as a critical and urgent requirement to integrate services across distributed, heterogeneous, dynamic "virtual organizations" formed by different resources within a single enterprise. In the last decade, Astronomy has become an immensely data rich field due to the evolution of detectors (plates to digital to mosaics), telescopes and space instruments. The Virtual Observatory approach consists into the federation under common standards of all astronomical archives available worldwide, as well as data analysis, data mining and data exploration applications. The main drive behind such effort being that once the infrastructure will be completed, it will allow a new type of multi-wavelength, multi-epoch science which can only be barely imagined. Data Mining, or Knowledge Discovery in Databases, while being the main methodology to extract the scientific information contained in such MDS (Massive Data Sets), poses crucial problems since it has to orchestrate complex problems posed by transparent access to different computing environments, scalability of algorithms, reusability of resources, etc. In the present paper we summarize the present status of the MDS in the Virtual Observatory and what is currently done and planned to bring advanced Data Mining methodologies in the case of the DAME (DAta Mining & Exploration) project.Comment: Pages 845-849 1rs International Conference on Frontiers in Diagnostics Technologie
    • …
    corecore