7,359 research outputs found
The Infectious Disease Ontology in the Age of COVID-19
The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health. IDO Core is designed to be a disease and pathogen neutral ontology, covering just those types of entities and relations that are relevant to infectious diseases generally. IDO Core is then extended by a collection of ontology modules focusing on specific diseases and pathogens. In this paper we present applications of IDO Core within various areas of infectious disease research, together with an overview of all IDO extension ontologies and the methodology on the basis of which they are built. We also survey recent developments involving IDO, including the creation of IDO Virus; the Coronaviruses Infectious Disease Ontology (CIDO); and an extension of CIDO focused on COVID-19 (IDO-CovID-19).We also discuss how these ontologies might assist in information-driven efforts to deal with the ongoing COVID-19 pandemic, to accelerate data discovery in the early stages of future pandemics, and to promote reproducibility of infectious disease research
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Proceedings ICPW'07: 2nd International Conference on the Pragmatic Web, 22-23 Oct. 2007, Tilburg: NL
Proceedings ICPW'07: 2nd International Conference on the Pragmatic Web, 22-23 Oct. 2007, Tilburg: N
Semantic reasoning for intelligent emergency response applications
Emergency response applications require the processing of large amounts of data, generated by a diverse set of sensors and devices, in order to provide for an accurate and concise view of the situation at hand. The adoption of semantic technologies allows for the definition of a formal domain model and intelligent data processing and reasoning on this model based on generated device and sensor measurements. This paper presents a novel approach to emergency response applications, such as fire fighting, integrating a formal semantic domain model into an event-based decision support system, which supports reasoning on this model. The developed model consists of several generic ontologies describing concepts and properties which can be applied to diverse context-aware applications. These are extended with emergency response specific ontologies. Additionally, inference on the model performed by a reasoning engine is dynamically synchronized with the rest of the architectural components. This allows to automatically trigger events based on predefined conditions. The proposed ontology and developed reasoning methodology is validated on two scenarios, i.e. (i) the construction of an emergency response incident and corresponding scenario and (ii) monitoring of the state of a fire fighter during an emergency response
A canonical theory of dynamic decision-making
Decision-making behavior is studied in many very different fields, from medicine and eco- nomics to psychology and neuroscience, with major contributions from mathematics and statistics, computer science, AI, and other technical disciplines. However the conceptual- ization of what decision-making is and methods for studying it vary greatly and this has resulted in fragmentation of the field. A theory that can accommodate various perspectives may facilitate interdisciplinary working. We present such a theory in which decision-making is articulated as a set of canonical functions that are sufficiently general to accommodate diverse viewpoints, yet sufficiently precise that they can be instantiated in different ways for specific theoretical or practical purposes. The canons cover the whole decision cycle, from the framing of a decision based on the goals, beliefs, and background knowledge of the decision-maker to the formulation of decision options, establishing preferences over them, and making commitments. Commitments can lead to the initiation of new decisions and any step in the cycle can incorporate reasoning about previous decisions and the rationales for them, and lead to revising or abandoning existing commitments. The theory situates decision-making with respect to other high-level cognitive capabilities like problem solving, planning, and collaborative decision-making. The canonical approach is assessed in three domains: cognitive and neuropsychology, artificial intelligence, and decision engineering
Constructing Ontology-Based Cancer Treatment Decision Support System with Case-Based Reasoning
Decision support is a probabilistic and quantitative method designed for
modeling problems in situations with ambiguity. Computer technology can be
employed to provide clinical decision support and treatment recommendations.
The problem of natural language applications is that they lack formality and
the interpretation is not consistent. Conversely, ontologies can capture the
intended meaning and specify modeling primitives. Disease Ontology (DO) that
pertains to cancer's clinical stages and their corresponding information
components is utilized to improve the reasoning ability of a decision support
system (DSS). The proposed DSS uses Case-Based Reasoning (CBR) to consider
disease manifestations and provides physicians with treatment solutions from
similar previous cases for reference. The proposed DSS supports natural
language processing (NLP) queries. The DSS obtained 84.63% accuracy in disease
classification with the help of the ontology
Ontology of core data mining entities
In this article, we present OntoDM-core, an ontology of core data mining
entities. OntoDM-core defines themost essential datamining entities in a three-layered
ontological structure comprising of a specification, an implementation and an application
layer. It provides a representational framework for the description of mining
structured data, and in addition provides taxonomies of datasets, data mining tasks,
generalizations, data mining algorithms and constraints, based on the type of data.
OntoDM-core is designed to support a wide range of applications/use cases, such as
semantic annotation of data mining algorithms, datasets and results; annotation of
QSAR studies in the context of drug discovery investigations; and disambiguation of
terms in text mining. The ontology has been thoroughly assessed following the practices
in ontology engineering, is fully interoperable with many domain resources and
is easy to extend
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