544,026 research outputs found
What (If Anything) Do Satisfaction Scores Tell Us about the Intertemporal Change in Living Conditions
This paper looks at the information content of satisfaction scores. It is argued that the information content depends on the extent to which people adapt to living conditions in general. Using data from the German Socio-Economic Panel Study (SOEP), the estimation of a dynamic panel data model provides evidence that adaptation takes place within a relatively short window of time: changes in living conditions are, for the most part, absorbed by an adjustment of the adaptation level within one year. This leads to the conclusion that the information content of satisfaction scores accentuates recent changes in living conditions. Remote changes are notcaptured by the according survey questions, even if these changes have long-term impact on living conditions. The usefulness of satisfaction scores as an indicator of people's living conditions is discussed.adaptation, dynamic panel data model, subjective well-being, satisfaction
Streaming Video QoE Modeling and Prediction: A Long Short-Term Memory Approach
HTTP based adaptive video streaming has become a popular choice of streaming
due to the reliable transmission and the flexibility offered to adapt to
varying network conditions. However, due to rate adaptation in adaptive
streaming, the quality of the videos at the client keeps varying with time
depending on the end-to-end network conditions. Further, varying network
conditions can lead to the video client running out of playback content
resulting in rebuffering events. These factors affect the user satisfaction and
cause degradation of the user quality of experience (QoE). It is important to
quantify the perceptual QoE of the streaming video users and monitor the same
in a continuous manner so that the QoE degradation can be minimized. However,
the continuous evaluation of QoE is challenging as it is determined by complex
dynamic interactions among the QoE influencing factors. Towards this end, we
present LSTM-QoE, a recurrent neural network based QoE prediction model using a
Long Short-Term Memory (LSTM) network. The LSTM-QoE is a network of cascaded
LSTM blocks to capture the nonlinearities and the complex temporal dependencies
involved in the time varying QoE. Based on an evaluation over several publicly
available continuous QoE databases, we demonstrate that the LSTM-QoE has the
capability to model the QoE dynamics effectively. We compare the proposed model
with the state-of-the-art QoE prediction models and show that it provides
superior performance across these databases. Further, we discuss the state
space perspective for the LSTM-QoE and show the efficacy of the state space
modeling approaches for QoE prediction
Ribosomal RNA diversity predicts genome diversity in gut bacteria and their relatives
The mammalian gut is an attractive model for exploring the general question of how habitat impacts the evolution of gene content. Therefore, we have characterized the relationship between 16 S rRNA gene sequence similarity and overall levels of gene conservation in four groups of species: gut specialists and cosmopolitans, each of which can be divided into pathogens and non-pathogens. At short phylogenetic distances, specialist or cosmopolitan bacteria found in the gut share fewer genes than is typical for genomes that come from non-gut environments, but at longer phylogenetic distances gut bacteria are more similar to each other than are genomes at equivalent evolutionary distances from non-gut environments, suggesting a pattern of short-term specialization but long-term convergence. Moreover, this pattern is observed in both pathogens and non-pathogens, and can even be seen in the plasmids carried by gut bacteria. This observation is consistent with the finding that, despite considerable interpersonal variation in species content, there is surprising functional convergence in the microbiome of different humans. Finally, we observe that even within bacterial species or genera 16S rRNA divergence provides useful information about average conservation of gene content. The results described here should be useful for guiding strain selection to maximize novel gene discovery in large-scale genome sequencing projects, while the approach could be applied in studies seeking to understand the effects of habitat adaptation on genome evolution across other body habitats or environment types
Improving content based image retrieval by identifying least and most correlated visual words
In this paper, we propose a model for direct incorporation of im- age content into a (short-term) user profile based on correlations between visual words and adaptation of the similarity measure. The relationships between visual words at different contextual levels are explored. We introduce and compare var- ious notions of correlation, which in general we will refer to as image-level and proximity-based. The information about the most and the least correlated visual words can be exploited in order to adapt the similarity measure. The evaluation, preceding an experiment involving real users (future work), is performed within the Pseudo Relevance Feedback framework. We test our new method on three large data collections, namely MIRFlickr, ImageCLEF, and a collection from British National Geological Survey (BGS). The proposed model is computation- ally cheap and scalable to large image collections
Understanding and Improving Older Male Participation and Older Adult Adherence in Evidence-Based Health Promotion Programs
The aging population and burden of chronic conditions have led researchers and practitioners to develop, implement, and evaluate evidence-based programs (EBPs) for older adults. The Healthy Aging Regional Collaborative (HARC) was established to make EBPs including Diabetes Self-Management Program, Chronic Disease Self-Management Program, Matter of Balance, and EnhanceFitness (EF) accessible in south Florida. According to the REAIM model, reach, effectiveness, adoption, implementation, and maintenance determine the impact of EBPs. Evaluation of HARC demonstrated widespread adoption of EBPs by community organizations that reached diverse participants and effectiveness among participants attending the recommended number of sessions, but only 19% of EBP participants were male, and only 25% of EF participants met attendance criteria for adherence. This mixed-methods dissertation explored program instructor and coordinator perspectives on barriers and strategies related to male participation in EBPs, examined predictors of short-term and long-term adherence to EF, and applied a theoretical framework to explore participant and instructor perspectives on factors influencing adherence to EF. Fourteen program coordinators participated in a focus group to identify barriers and strategies to improve male participation, and 49 instructors participated in a survey to triangulate findings. Themes among barriers to male participation included women outnumbering men in programs, incompatibility of programs with male gender roles, and preference for other activities. Themes among strategies included endorsement by male community leaders, advertisements featuring males, and content adaptation. Among 5,619 EF participants, logistic regression confirmed age, race/ethnicity, gender, and health status as significant predictors of adherence. The likelihood of short-term and long-term adherence increased with age and health. Black participants were less likely than whites to adhere short-term (OR=0.82, p=.05) but more likely to adhere long-term (OR=1.77, p=.000). Hispanics were more likely than whites to adhere short-term (OR=1.25, p=.008) and long-term (OR=1.30, p=.001). Men were more likely to meet the criteria for short-term (OR=1.47, p=.001) and long-term adherence (OR=1.19, p=.04). Interviews with 12 adherent EF participants and 10 instructors revealed cues to action, goals, beliefs, intentions, program factors, social factors, and benefits that supported adherence. Findings inform efforts to improve participation and adherence in EBPs and maximize their impact on health among older adults
Ventricular structure, function, and mechanics at high altitude: chronic remodeling in Sherpa vs. short-term lowlander adaptation
Short-term, high-altitude (HA) exposure raises pulmonary artery systolic pressure (PASP) and decreases left-ventricular (LV) volumes. However, relatively little is known of the long-term cardiac consequences of prolonged exposure in Sherpa, a highly adapted HA population. To investigate short-term adaptation and potential long-term cardiac remodeling, we studied ventricular structure and function in Sherpa at 5,050 m (n = 11; 31 ± 13 yr; mass 68 ± 10 kg; height 169 ± 6 cm) and lowlanders at sea level (SL) and following 10 ± 3 days at 5,050 m (n = 9; 34 ± 7 yr; mass 82 ± 10 kg; height 177 ± 6 cm) using conventional and speckle-tracking echocardiography. At HA, PASP was higher in Sherpa and lowlanders compared with lowlanders at SL (both P < 0.05). Sherpa had smaller right-ventricular (RV) and LV stroke volumes than lowlanders at SL with lower RV systolic strain (P < 0.05) but similar LV systolic mechanics. In contrast to LV systolic mechanics, LV diastolic, untwisting velocity was significantly lower in Sherpa compared with lowlanders at both SL and HA. After partial acclimatization, lowlanders demonstrated no change in the RV end-diastolic area; however, both RV strain and LV end-diastolic volume were reduced. In conclusion, short-term hypoxia induced a reduction in RV systolic function that was also evident in Sherpa following chronic exposure. We propose that this was consequent to a persistently higher PASP. In contrast to the RV, remodeling of LV volumes and normalization of systolic mechanics indicate structural and functional adaptation to HA. However, altered LV diastolic relaxation after chronic hypoxic exposure may reflect differential remodeling of systolic and diastolic LV function.
exposure to high altitude (HA) challenges the cardiovascular system to meet the metabolic demand for oxygen (O2) in an environment where arterial O2 content is markedly reduced. The drop in arterial O2 has both direct and indirect consequences for the heart, including depressed inotropy of cardiac muscle (40, 44), changes in blood volume and viscosity, and vasoconstriction of the pulmonary arteries (33). Despite these broad physiological changes, which have been reviewed previously (28, 49), there is evidence that the heart copes relatively well at HA (29, 34).
Short-term HA exposure in lowland natives is characterized by a decreased plasma volume (PV), an increased sympathetic nerve activity, and pulmonary vasoconstriction (17, 30, 37), all of which have considerable impact on cardiac function and in time, could stimulate cardiac remodeling. Himalayan native Sherpa, who are of Tibetan lineage and have resided at HA for ∼25,000 yr (2), are well adapted to life at HA, demonstrating greater lung-diffusing capacity (11) and an absence of polycythemia compared with acclimatized lowlanders (4). Previous studies have also reported Sherpa to have higher maximal heart rates (HRs) and only moderate pulmonary hypertension compared with lowlanders at HA (11, 25). Due to their longevity at HA, Sherpa provide an excellent model to investigate the effects of chronic hypoxic exposure. Despite this, neither the acute nor lifelong effects of HA on right- and left-ventricular (RV and LV, respectively) structure and function have been fully assessed in lowlanders or the unique Sherpa population.
Due to the unique arrangement of myofibers, cardiac form and function are intrinsically linked, as reflected in the cardiac mechanics (LV twist and rotation and ventricular strain) that underpin ventricular function. In response to altered physiological demand, ventricular mechanics acutely change (16, 41) and chronically remodel (31, 42) to reduce myofiber stress and achieve efficient ejection (5, 47). Therefore, concomitant examination of myocardial mechanics and ventricular structure in both the acute and chronic HA setting will provide novel insight into human adaptation to hypoxia.
To investigate the effects of chronic hypoxic exposure, we compared ventricular volumes and mechanics in Sherpa at 5,050 m with lowlanders at sea level (SL). In addition, to reveal potential stimuli for remodeling and to examine the time course of adaptation, we compared Sherpa with lowlanders after short-term HA exposure.
We hypothesized that: 1) Sherpa would exhibit smaller LV volumes and a higher RV/LV ratio than lowlanders at SL, 2) LV mechanics in Sherpa will closely resemble those of lowlanders at SL, and 3) following partial acclimatization to HA, LV volumes would be reduced in lowlanders and LV mechanics acutely increased
Topography induced spatial variations in diurnal cycles of assimilation and latent heat of Mediterranean forest
The aim of this study is to explain topography induced spatial variations in the diurnal cycles of assimilation and latent heat of Mediterranean forest. Spatial variations of the fluxes are caused by variations in weather conditions and in vegetation characteristics. Weather conditions reflect short-term effects of climate, whereas vegetation characteristics, through adaptation and acclimation, long-term effects of climate. In this study measurements of plant physiology and weather conditions are used to explain observed differences in the fluxes. A model is used to study which part of the differences in the fluxes is caused by weather conditions and which part by vegetation characteristics. Data were collected at four experimental sub-Mediterranean deciduous forest plots in a heterogeneous terrain with contrasting aspect, soil water availability, humidity and temperature. We used a sun-shade model to scale fluxes from leaf to canopy, and calculated the canopy energy balance. Parameter values were derived from measurements of light interception, leaf chamber photosynthesis, leaf nitrogen content and <sup>13</sup>C isotope discrimination in leaf material. Leaf nitrogen content is a measure of photosynthetic capacity, and <sup>13</sup>C isotope discrimination of water use efficiency. For validation, sap-flux based measurements of transpiration were used. The model predicted diurnal cycles of transpiration and stomatal conductance, both their magnitudes and differences in afternoon stomatal closure between slopes of different aspect within the confidence interval of the validation data. Weather conditions mainly responsible for the shape of the diurnal cycles, and vegetation parameters for the magnitude of the fluxes. Although the data do not allow for a quantification of the two effects, the differences in vegetation parameters and weather among the plots and the sensitivity of the fluxes to them suggest that the diurnal cycles were more strongly affected by spatial variations in vegetation parameters than by meteorological variables. This indicates that topography induced variations in vegetation parameters are of equal importance to the fluxes as topography induced variations in radiation, humidity and temperature
Towards Affordable Disclosure of Spoken Word Archives
This paper presents and discusses ongoing work aiming at affordable disclosure of real-world spoken word archives in general, and in particular of a collection of recorded interviews with Dutch survivors of World War II concentration camp Buchenwald. Given such collections, the least we want to be able to provide is search at different levels and a flexible way of presenting results. Strategies for automatic annotation based on speech recognition – supporting e.g., within-document search– are outlined and discussed with respect to the Buchenwald interview collection. In addition, usability aspects of the spoken word search are discussed on the basis of our experiences with the online Buchenwald web portal. It is concluded that, although user feedback is generally fairly positive, automatic annotation performance is still far from satisfactory, and requires additional research
Plastic and evolutionary responses of Chlamydomonas reinhardtii to multiple environmental drivers
In my thesis I present data collected from a long-term selection experiment using the
freshwater model organism Chlamydomonas reinhardtii. The selection experiment
was designed to disentangle the effects of the number of multiple environmental
drivers (MEDs) and the identity of those environmental drivers including high CO2,
high temperature, general nutrient depletion, reduced light intensity, reduced
phosphate availability, the addition of a herbicide, UV radiation and reduced pH.
Using up to eight environmental drivers, I show how simple organisms such as C.
reinhardtii evolve in response to MEDs.
The first step in this investigation is to examine the short-term response of MEDs.
Data collected at the beginning of the selection experiment will provide insight into
the early stages of microevolution by investigating key differences in the short-term
(plastic) responses to few vs. many MEDs. Here, I focus on how the data collected
from the responses to single environmental drivers can help us predict the responses
to MEDs by using ecological models (additive, comparative, multiplicative). I show
that the short-term plastic responses to single environmental drivers can predict the
effect of MEDs using the comparative model because the response is largely driven
by the single dominant driver present. I also demonstrate the importance of the
number of environmental drivers (NED) for making predictions from the single
environmental drivers and show that predictions become more reliable as the NED
increases. The results gathered from short-term responses provide evidence that
single environmental driver studies are useful for predicting the effect of MEDs.
After evolution, I found that the strength of selection varies with NED in a
predictable way, which connects the NED to the evolutionary response (size of the
direct response) through the strength of selection. Here, I used statistical models to
quantify the effect of NED on the evolutionary response to MEDs and then
interpreted this by considering the possible genetic constraints on adaptation to
MEDs.
A subset of populations evolved in environments with five environmental drivers and
all populations evolved in the single environmental driver environments are used to
examine how adapting to single vs. many environmental drivers affect local
adaptation. I examine how populations selected in environments with one
environmental driver, five environmental drivers and the evolved control, differ in
their response to new environments with the same NED, environments with different
NED, and a novel environment. I found that there is a relationship between local
adaptation and the strength of selection in the local environment and patterns of local
adaptation are affected by the NED of new environments. Lastly, I present the
phenotypic consequences of evolution under MEDs. I found that before evolution,
measures of chlorophyll content and cell size decline with increasing NED.
However, after evolution the relationship between chlorophyll content and cell size
with NED is weaker because populations converge on the same phenotypes as they
evolve. I also present a case-study of how mass spectrometry methods can be used
to better understand underlying molecular mechanisms of two phenotypes
(chlorophyll positive and chlorophyll negative cells).
This selection experiment is a good example of how laboratory investigations and
model organisms can be used to design experiments with enough replication to have
high statistical power in order to make more accurate predictions on the short- long-term
effects of MEDs. Whilst there have been some studies on the effects of MEDs,
these studies rarely have more than three environmental drivers (sometimes 5
environmental drivers) and there are only a handful of long-term MED studies. This
study can be used to develop a priori hypotheses for investigating how
environmental change will shape natural microbial communities, and is especially
useful for organisms where long-term studies with multiple environmental drivers
are unfeasible
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