Learning-Based Matheuristic Solution Methods for Stochastic Network Design

Cette dissertation consiste en trois études, chacune constituant un article de recherche. Dans tous les trois articles, nous considérons le problème de conception de réseaux multiproduits, avec coût fixe, capacité et des demandes stochastiques en tant que programmes stochastiques en deux étapes. Dans un tel contexte, les décisions de conception sont prises dans la première étape avant que la demande réelle ne soit réalisée, tandis que les décisions de flux de la deuxième étape ajustent la solution de la première étape à la réalisation de la demande observée. Nous considérons l’incertitude de la demande comme un nombre fini de scénarios discrets, ce qui est une approche courante dans la littérature. En utilisant l’ensemble de scénarios, le problème mixte en nombre entier (MIP) résultant, appelé formulation étendue (FE), est extrêmement difficile à résoudre, sauf dans des cas triviaux. Cette thèse vise à faire progresser le corpus de connaissances en développant des algorithmes efficaces intégrant des mécanismes d’apprentissage en matheuristique, capables de traiter efficacement des problèmes stochastiques de conception pour des réseaux de grande taille. Le premier article, s’intitulé "A Learning-Based Matheuristc for Stochastic Multicommodity Network Design". Nous introduisons et décrivons formellement un nouveau mécanisme d’apprentissage basé sur l’optimisation pour extraire des informations concernant la structure de la solution du problème stochastique à partir de solutions obtenues avec des combinaisons particulières de scénarios. Nous proposons ensuite une matheuristique "Learn&Optimize", qui utilise les méthodes d’apprentissage pour déduire un ensemble de variables de conception prometteuses, en conjonction avec un solveur MIP de pointe pour résoudre un problème réduit. Le deuxième article, s’intitulé "A Reduced-Cost-Based Restriction and Refinement Matheuristic for Stochastic Network Design". Nous étudions comment concevoir efficacement des mécanismes d’apprentissage basés sur l’information duale afin de guider la détermination des variables dans le contexte de la conception de réseaux stochastiques. Ce travail examine les coûts réduits associés aux variables hors base dans les solutions déterministes pour guider la sélection des variables dans la formulation stochastique. Nous proposons plusieurs stratégies pour extraire des informations sur les coûts réduits afin de fixer un ensemble approprié de variables dans le modèle restreint. Nous proposons ensuite une approche matheuristique utilisant des techniques itératives de réduction des problèmes. Le troisième article, s’intitulé "An Integrated Learning and Progressive Hedging Method to Solve Stochastic Network Design". Ici, notre objectif principal est de concevoir une méthode de résolution capable de gérer un grand nombre de scénarios. Nous nous appuyons sur l’algorithme Progressive Hedging (PHA), ou les scénarios sont regroupés en sous-problèmes. Nous intégrons des methodes d’apprentissage au sein de PHA pour traiter une grand nombre de scénarios. Dans notre approche, les mécanismes d’apprentissage developpés dans le premier article de cette thèse sont adaptés pour résoudre les sous-problèmes multi-scénarios. Nous introduisons une nouvelle solution de référence à chaque étape d’agrégation de notre ILPH en exploitant les informations collectées à partir des sous problèmes et nous utilisons ces informations pour mettre à jour les pénalités dans PHA. Par conséquent, PHA est guidé par les informations locales fournies par la procédure d’apprentissage, résultant en une approche intégrée capable de traiter des instances complexes et de grande taille. Dans les trois articles, nous montrons, au moyen de campagnes expérimentales approfondies, l’intérêt des approches proposées en termes de temps de calcul et de qualité des solutions produites, en particulier pour traiter des cas très difficiles avec un grand nombre de scénarios.This dissertation consists of three studies, each of which constitutes a self-contained research article. In all of the three articles, we consider the multi-commodity capacitated fixed-charge network design problem with uncertain demands as a two-stage stochastic program. In such setting, design decisions are made in the first stage before the actual demand is realized, while second-stage flow-routing decisions adjust the first-stage solution to the observed demand realization. We consider the demand uncertainty as a finite number of discrete scenarios, which is a common approach in the literature. By using the scenario set, the resulting large-scale mixed integer program (MIP) problem, referred to as the extensive form (EF), is extremely hard to solve exactly in all but trivial cases. This dissertation is aimed at advancing the body of knowledge by developing efficient algorithms incorporating learning mechanisms in matheuristics, which are able to handle large scale instances of stochastic network design problems efficiently. In the first article, we propose a novel Learning-Based Matheuristic for Stochastic Network Design Problems. We introduce and formally describe a new optimizationbased learning mechanism to extract information regarding the solution structure of a stochastic problem out of the solutions of particular combinations of scenarios. We subsequently propose the Learn&Optimize matheuristic, which makes use of the learning methods in inferring a set of promising design variables, in conjunction with a state-ofthe- art MIP solver to address a reduced problem. In the second article, we introduce a Reduced-Cost-Based Restriction and Refinement Matheuristic. We study on how to efficiently design learning mechanisms based on dual information as a means of guiding variable fixing in the context of stochastic network design. The present work investigates how the reduced cost associated with non-basic variables in deterministic solutions can be leveraged to guide variable selection within stochastic formulations. We specifically propose several strategies to extract reduced cost information so as to effectively identify an appropriate set of fixed variables within a restricted model. We then propose a matheuristic approach using problem reduction techniques iteratively (i.e., defining and exploring restricted region of global solutions, as guided by applicable dual information). Finally, in the third article, our main goal is to design a solution method that is able to manage a large number of scenarios. We rely on the progressive hedging algorithm (PHA) where the scenarios are grouped in subproblems. We propose a two phase integrated learning and progressive hedging (ILPH) approach to deal with a large number of scenarios. Within our proposed approach, the learning mechanisms from the first study of this dissertation have been adapted as an efficient heuristic method to address the multi-scenario subproblems within each iteration of PHA.We introduce a new reference point within each aggregation step of our proposed ILPH by exploiting the information garnered from subproblems, and using this information to update the penalties. Consequently, the ILPH is governed and guided by the local information provided by the learning procedure, resulting in an integrated approach capable of handling very large and complex instances. In all of the three mentioned articles, we show, by means of extensive experimental campaigns, the interest of the proposed approaches in terms of computation time and solution quality, especially in dealing with very difficult instances with a large number of scenarios

Lagrangian-based methods for single and multi-layer multicommodity capacitated network design

Le problème de conception de réseau avec coûts fixes et capacités (MCFND) et le problème de conception de réseau multicouches (MLND) sont parmi les problèmes de conception de réseau les plus importants. Dans le problème MCFND monocouche, plusieurs produits doivent être acheminés entre des paires origine-destination différentes d’un réseau potentiel donné. Des liaisons doivent être ouvertes pour acheminer les produits, chaque liaison ayant une capacité donnée. Le problème est de trouver la conception du réseau à coût minimum de sorte que les demandes soient satisfaites et que les capacités soient respectées. Dans le problème MLND, il existe plusieurs réseaux potentiels, chacun correspondant à une couche donnée. Dans chaque couche, les demandes pour un ensemble de produits doivent être satisfaites. Pour ouvrir un lien dans une couche particulière, une chaîne de liens de support dans une autre couche doit être ouverte. Nous abordons le problème de conception de réseau multiproduits multicouches à flot unique avec coûts fixes et capacités (MSMCFND), où les produits doivent être acheminés uniquement dans l’une des couches. Les algorithmes basés sur la relaxation lagrangienne sont l’une des méthodes de résolution les plus efficaces pour résoudre les problèmes de conception de réseau. Nous présentons de nouvelles relaxations à base de noeuds, où le sous-problème résultant se décompose par noeud. Nous montrons que la décomposition lagrangienne améliore significativement les limites des relaxations traditionnelles. Les problèmes de conception du réseau ont été étudiés dans la littérature. Cependant, ces dernières années, des applications intéressantes des problèmes MLND sont apparues, qui ne sont pas couvertes dans ces études. Nous présentons un examen des problèmes de MLND et proposons une formulation générale pour le MLND. Nous proposons également une formulation générale et une méthodologie de relaxation lagrangienne efficace pour le problème MMCFND. La méthode est compétitive avec un logiciel commercial de programmation en nombres entiers, et donne généralement de meilleurs résultats.The multicommodity capacitated fixed-charge network design problem (MCFND) and the multilayer network design problem (MLND) are among the most important network design problems. In the single-layer MCFND problem, several commodities have to be routed between different origin-destination pairs of a given potential network. Appropriate capacitated links have to be opened to route the commodities. The problem is to find the minimum cost design and routing such that the demands are satisfied and the capacities are respected. In the MLND, there are several potential networks, each at a given layer. In each network, the flow requirements for a set of commodities must be satisfied. However, the selection of the links is interdependent. To open a link in a particular layer, a chain of supporting links in another layer has to be opened. We address the multilayer single flow-type multicommodity capacitated fixed-charge network design problem (MSMCFND), where commodities are routed only in one of the layers. Lagrangian-based algorithms are one of the most effective solution methods to solve network design problems. The traditional Lagrangian relaxations for the MCFND problem are the flow and knapsack relaxations, where the resulting Lagrangian subproblems decompose by commodity and by arc, respectively. We present new node-based relaxations, where the resulting subproblem decomposes by node. We show that the Lagrangian dual bound improves significantly upon the bounds of the traditional relaxations. We also propose a Lagrangian-based algorithm to obtain upper bounds. Network design problems have been the object of extensive literature reviews. However, in recent years, interesting applications of multilayer problems have appeared that are not covered in these surveys. We present a review of multilayer problems and propose a general formulation for the MLND. We also propose a general formulation and an efficient Lagrangian-based solution methodology for the MMCFND problem. The method is competitive with (and often significantly better than) a state-of-the-art mixedinteger programming solver on a large set of randomly generated instances

A new algorithm for optimal solution of fixed charge transportation problem

summary:Fixed charge transportation problem (FCTP) is a supply chain problem. In this problem, in addition to the cost per unit for each transported product, a fixed cost is also required. The aim is to carry out the transportation process at the lowest possible cost. As with all supply chain problems, this problem may have one, two, or three stages. An algorithm that can find the optimal solution for the problem in polynomial time is not known, even if it is a single-stage problem. For this reason, new algorithms have been proposed in recent years to provide an approximate solution for the problem. The vast majority of these algorithms are meta-heuristic algorithms. In this study, we propose a new heuristic algorithm to find an optimal solution for the 1-stage FCTP. We compare the results of our algorithm with the results of other existing algorithms

Models and Algorithms for the Optimisation of Replenishment, Production and Distribution Plans in Industrial Enterprises

Tesis por compendio[ES] La optimización en las empresas manufactureras es especialmente importante, debido a las grandes inversiones que realizan, ya que a veces estas inversiones no obtienen el rendimiento esperado porque los márgenes de beneficio de los productos son muy ajustados. Por ello, las empresas tratan de maximizar el uso de los recursos productivos y financieros minimizando el tiempo perdido y, al mismo tiempo, mejorando los flujos de los procesos y satisfaciendo las necesidades del mercado. El proceso de planificación es una actividad crítica para las empresas. Esta tarea implica grandes retos debido a los cambios del mercado, las alteraciones en los procesos de producción dentro de la empresa y en la cadena de suministro, y los cambios en la legislación, entre otros. La planificación del aprovisionamiento, la producción y la distribución desempeña un papel fundamental en el rendimiento de las empresas manufactureras, ya que una planificación ineficaz de los proveedores, los procesos de producción y los sistemas de distribución contribuye a aumentar los costes de los productos, a alargar los plazos de entrega y a reducir los beneficios. La planificación eficaz es un proceso complejo que abarca una amplia gama de actividades para garantizar que los equipos, los materiales y los recursos humanos estén disponibles en el momento y el lugar adecuados. Motivados por la complejidad de la planificación en las empresas manufactureras, esta tesis estudia y desarrolla herramientas cuantitativas para ayudar a los planificadores en los procesos de la planificación del aprovisionamiento, producción y distribución. Desde esta perspectiva, se proponen modelos realistas y métodos eficientes para apoyar la toma de decisiones en las empresas industriales, principalmente en las pequeñas y medianas empresas (PYMES). Las aportaciones de esta tesis suponen un avance científico basado en una exhaustiva revisión bibliográfica sobre la planificación del aprovisionamiento, la producción y la distribución que ayuda a comprender los principales modelos y algoritmos utilizados para resolver estos planes, y pone en relieve las tendencias y las futuras direcciones de investigación. También proporciona un marco holístico para caracterizar los modelos y algoritmos centrándose en la planificación de la producción, la programación y la secuenciación. Esta tesis también propone una herramienta de apoyo a la decisión para seleccionar un algoritmo o método de solución para resolver problemas concretos de la planificación del aprovisionamiento, producción y distribución en función de su complejidad, lo que permite a los planificadores no duplicar esfuerzos de modelización o programación de técnicas de solución. Por último, se desarrollan nuevos modelos matemáticos y enfoques de solución de última generación, como los algoritmos matheurísticos, que combinan la programación matemática y las técnicas metaheurísticas. Los nuevos modelos y algoritmos comprenden mejoras en términos de rendimiento computacional, e incluyen características realistas de los problemas del mundo real a los que se enfrentan las empresas de fabricación. Los modelos matemáticos han sido validados con un caso de una importante empresa del sector de la automoción en España, lo que ha permitido evaluar la relevancia práctica de estos novedosos modelos utilizando instancias de gran tamaño, similares a las existentes en la empresa objeto de estudio. Además, los algoritmos matheurísticos han sido probados utilizando herramientas libres y de código abierto. Esto también contribuye a la práctica de la investigación operativa, y proporciona una visión de cómo desplegar estos métodos de solución y el tiempo de cálculo y rendimiento de la brecha que se puede obtener mediante el uso de software libre o de código abierto.[CA] L'optimització a les empreses manufactureres és especialment important, a causa de les grans inversions que realitzen, ja que de vegades aquestes inversions no obtenen el rendiment esperat perquè els marges de benefici dels productes són molt ajustats. Per això, les empreses intenten maximitzar l'ús dels recursos productius i financers minimitzant el temps perdut i, alhora, millorant els fluxos dels processos i satisfent les necessitats del mercat. El procés de planificació és una activitat crítica per a les empreses. Aquesta tasca implica grans reptes a causa dels canvis del mercat, les alteracions en els processos de producció dins de l'empresa i la cadena de subministrament, i els canvis en la legislació, entre altres. La planificació de l'aprovisionament, la producció i la distribució té un paper fonamental en el rendiment de les empreses manufactureres, ja que una planificació ineficaç dels proveïdors, els processos de producció i els sistemes de distribució contribueix a augmentar els costos dels productes, allargar els terminis de lliurament i reduir els beneficis. La planificació eficaç és un procés complex que abasta una àmplia gamma d'activitats per garantir que els equips, els materials i els recursos humans estiguen disponibles al moment i al lloc adequats. Motivats per la complexitat de la planificació a les empreses manufactureres, aquesta tesi estudia i desenvolupa eines quantitatives per ajudar als planificadors en els processos de la planificació de l'aprovisionament, producció i distribució. Des d'aquesta perspectiva, es proposen models realistes i mètodes eficients per donar suport a la presa de decisions a les empreses industrials, principalment a les petites i mitjanes empreses (PIMES). Les aportacions d'aquesta tesi suposen un avenç científic basat en una exhaustiva revisió bibliogràfica sobre la planificació de l'aprovisionament, la producció i la distribució que ajuda a comprendre els principals models i algorismes utilitzats per resoldre aquests plans, i posa de relleu les tendències i les futures direccions de recerca. També proporciona un marc holístic per caracteritzar els models i algorismes centrant-se en la planificació de la producció, la programació i la seqüenciació. Aquesta tesi també proposa una eina de suport a la decisió per seleccionar un algorisme o mètode de solució per resoldre problemes concrets de la planificació de l'aprovisionament, producció i distribució en funció de la seua complexitat, cosa que permet als planificadors no duplicar esforços de modelització o programació de tècniques de solució. Finalment, es desenvolupen nous models matemàtics i enfocaments de solució d'última generació, com ara els algoritmes matheurístics, que combinen la programació matemàtica i les tècniques metaheurístiques. Els nous models i algoritmes comprenen millores en termes de rendiment computacional, i inclouen característiques realistes dels problemes del món real a què s'enfronten les empreses de fabricació. Els models matemàtics han estat validats amb un cas d'una important empresa del sector de l'automoció a Espanya, cosa que ha permés avaluar la rellevància pràctica d'aquests nous models utilitzant instàncies grans, similars a les existents a l'empresa objecte d'estudi. A més, els algorismes matheurístics han estat provats utilitzant eines lliures i de codi obert. Això també contribueix a la pràctica de la investigació operativa, i proporciona una visió de com desplegar aquests mètodes de solució i el temps de càlcul i rendiment de la bretxa que es pot obtindre mitjançant l'ús de programari lliure o de codi obert.[EN] Optimisation in manufacturing companies is especially important, due to the large investments they make, as sometimes these investments do not obtain the expected return because the profit margins of products are very tight. Therefore, companies seek to maximise the use of productive and financial resources by minimising lost time and, at the same time, improving process flows while meeting market needs. The planning process is a critical activity for companies. This task involves great challenges due to market changes, alterations in production processes within the company and in the supply chain, and changes in legislation, among others. Planning of replenishment, production and distribution plays a critical role in the performance of manufacturing companies because ineffective planning of suppliers, production processes and distribution systems contributes to higher product costs, longer lead times and less profits. Effective planning is a complex process that encompasses a wide range of activities to ensure that equipment, materials and human resources are available in the right time and the right place. Motivated by the complexity of planning in manufacturing companies, this thesis studies and develops quantitative tools to help planners in the replenishment, production and delivery planning processes. From this perspective, realistic models and efficient methods are proposed to support decision making in industrial companies, mainly in small- and medium-sized enterprises (SMEs). The contributions of this thesis represent a scientific breakthrough based on a comprehensive literature review about replenishment, production and distribution planning that helps to understand the main models and algorithms used to solve these plans, and highlights trends and future research directions. It also provides a holistic framework to characterise models and algorithms by focusing on production planning, scheduling and sequencing. This thesis also proposes a decision support tool for selecting an algorithm or solution method to solve concrete replenishment, production and distribution planning problems according to their complexity, which allows planners to not duplicate efforts modelling or programming solution techniques. Finally, new state-of-the-art mathematical models and solution approaches are developed, such as matheuristic algorithms, which combine mathematical programming and metaheuristic techniques. The new models and algorithms comprise improvements in computational performance terms, and include realistic features of real-world problems faced by manufacturing companies. The mathematical models have been validated with a case of an important company in the automotive sector in Spain, which allowed to evaluate the practical relevance of these novel models using large instances, similarly to those existing in the company under study. In addition, the matheuristic algorithms have been tested using free and open-source tools. This also helps to contribute to the practice of operations research, and provides insight into how to deploy these solution methods and the computational time and gap performance that can be obtained by using free or open-source software.This work would not have been possible without the following funding sources: Conselleria de Educación, Investigación, Cultura y Deporte, Generalitat Valenciana for hiring predoctoral research staff with Grant (ACIF/2018/170) and the European Social Fund with the Grant Operational Programme of FSE 2014-2020. Conselleria de Educación, Investigación, Cultura y Deporte, Generalitat Valenciana for predoctoral contract students to stay in research centers outside the research centers outside the Valencian Community (BEFPI/2021/040) and the European Social Fund.Guzmán Ortiz, BE. (2022). Models and Algorithms for the Optimisation of Replenishment, Production and Distribution Plans in Industrial Enterprises [Tesis doctoral]. Universitat Politècnica de València. https://doi.org/10.4995/Thesis/10251/187461Compendi

Risk-Based Optimal Scheduling for the Predictive Maintenance of Railway Infrastructure

In this thesis a risk-based decision support system to schedule the predictive maintenance activities, is proposed. The model deals with the maintenance planning of a railway infrastructure in which the due-dates are defined via failure risk analysis.The novelty of the approach consists of the risk concept introduction in railway maintenance scheduling, according to ISO 55000 guidelines, thus implying that the maintenance priorities are based on asset criticality, determined taking into account the relevant failure probability, related to asset degradation conditions, and the consequent damages

Recharge strategies for the electric vehicle routing problem with time windows in deterministic and stochastic environments

Due to increasing concerns about greenhouse gas emissions in recent years, many companies have had an interest in using alternative fuel vehicles in their fleets. Electric vehicles (EVs) are one of these vehicles and they have various advantages such as zero tailpipe emissions, low maintenance costs and low energy consumption. However, their acquisition costs are higher compared to the conventional vehicles and recharging the battery may take significant amount of time compared to the short fueling times. Hence, to overcome these challenges, logistics decisions have to be made effectively. The problem of planning EVs’ activities has been introduced to the literature as the Electric Vehicle Routing Problem (EVRP), which is a special case of the classical VRP where the fleet consists of EVs. The difference between this problem and the classical VRP is that vehicles have batteries as the energy source and the battery is being discharged while the EV is traveling. Hence, the EVs may recharge their batteries at the recharging stations to continue their routes. These stations are located at distant locations and there are few of them compared to the common fuel stations. Recharging may be performed at any level of the battery and the recharging time increases with the recharge amount. In some stations, there may be different chargers which vary in terms of charging speed. For instance, fast chargers recharge the battery faster, but they incur higher cost. Furthermore, EVs may wait in the queue at the stations since there may be other EVs which arrive earlier and wait for ii service. In this dissertation, we address four problems which consider these different features of the EVRP. First, we study the EVRP with Time Windows where the batteries can be recharged partially at the recharging stations. Second, we extend this problem where the recharging stations are equipped with multiple types of chargers which differ by recharging rates and unit recharging costs. Next, we consider a stochastic environment where an EV may wait in the queue before recharging due to other EVs that have arrived earlier at that station. The waiting times depend on the time of the visit during the day, i.e., they are longer in the rush hours. Furthermore, the recharging time is assumed to be a nonlinear function of the energy recharged. In the final problem, we consider random waiting times at the recharging stations. In this case, the EVs do not have information about the queue lengths of the stations before they arrive at. We propose Adaptive Large Neighborhood Search heuristics and matheuristics to solve these problems effectivel

Truckload Shipment Planning and Procurement

This dissertation presents three issues encountered by a shipper in the context of truckload transportation. In all of the studies, we utilize optimization techniques to model and solve the problems. Each study is inspired from the real world and much of the data used in the experiments is real data or representative of real data. The first topic is about the freight consolidation in truckload transportation. We integrate it with a purchase incentive program to increase truckload utilization and maximize profit. The second topic is about supporting decision making collaboration among departments of a manufacturer. It is a bi-objective optimization model. The third topic is about procurement in an adverse market. We study a modification of the existing procurement process to consider the market stochastic into marking decisions. In all three studies, our target is to develop effectively methodologies to seek optimal answers within a reasonable amount of time

Mathematical optimization and learning models to address uncertainties and sustainability of supply chain management

As concerns about climate change, biodiversity loss, and pollution have become more widespread, new worldwide challenges deal with the protection of the environment and the conservation of natural resources. Thus, in order to empower sustainability and circular economy ambitions, the world has shifted to embrace sustainable practices and policies. This is carried out, primarily, through the implementation of sustainable business practices and increased investments in green technology. Advanced information systems, digital technologies and mathematical models are required to respond to the demanding targets of the sustainability paradigm. This trend is expanding with the growing interest in production and services sustainability in order to achieve economic growth and development while preventing their negative impact on the environment. A significant step forward in this direction is enabled by Supply Chain Management (SCM) practices that exploit mathematical and statistical modeling to better support decisions affecting both profitability and sustainability targets. Indeed, these targets should not be approached as competing goals, but rather addressed simultaneously within a comprehensive vision that responds adequately to both of them. Accordingly, Green Supply Chain Management (GSCM) can achieve its goals through innovative management approaches that consider sustainable efficiency and profitability to be clearly linked by the savings that result from applying optimization techniques. To confirm the above, there is a growing trend of applying mathematical optimization models for enhancing decision-making in pursuit of both environmental and profit performance. Indeed, GSCM takes into account many decision problems, such as facility location, capacity allocation, production planning and vehicle routing. Besides sustainability, uncertainty is another critical issue in Supply Chain Management (SCM). Considering a deterministic approach would definitely fail to provide concrete decision support when modeling those kinds of scenarios. According to various hypothesis and strategies, uncertainties can be addressed by exploiting several modeling approaches arising from statistics, statistical learning and mathematical programming. While statistical and learning models accounts variability by definition, Robust Optimization (RO) is a particular modeling approach that is commonly applied in solving mathematical programming problems where a certain set of parameters are subject to uncertainty. In this dissertation, mathematical and learning models are exploited according to different approaches and models combinations, providing new formulations and frameworks to address strategic and operational problems of GSCM under uncertainty. All models and frameworks presented in this dissertation are tested and validated on real-case instances

Stochastic Service Network Design for Intermodal Freight Transportation

In view of the accelerating climate change, greenhouse gas emissions from freight transportation must be significantly reduced over the next decades. Intermodal transportation can make a significant contribution here. During the transportation process, different modes of transportation are combined, enabling a modal shift to environmentally friendly alternatives such as rail and inland waterway transportation. However, at the same time, the organization of several modes is more complex compared to the unimodal case (where, for example, only trucks are employed). In particular, an efficient management of uncertainties, such as fluctuating transportation demand volumes or delays, is required to realize low costs and transportation times, thereby ensuring the attractiveness of intermodal transportation for a further modal shift. Stochastic service network design can explicitly consider such uncertainities in the planning in order to increase the performance of intermodal transportation. Decisions for the network design as well as for the mode choice are defined by mathematical optimization models, which originate from operations research and include relevant uncertainities by stochastic parameters. As central research gap, this dissertation addresses important operational constraints and decision variables of real-life intermodal networks, which have not been considered in these models so far and, in consequence, strongly limit their application in everyday operations. The resulting research contribution are two new variants of stochastic service network design models: The "stochastic service network design with integrated vehicle routing problem" integrates corresponding routing problems for road vehicles into the planning of intermodal networks. This new variant ensures a cost- and delay-minimal mode choice in the case of uncertain transportation times. The "stochastic service network design with short-term schedule modifications" deals with modifications of intermodal transportation schedules in order to adapt them to fluctuating demand as best as possible. For both new model variants, heuristic solution methods are presented which can efficiently solve even large network instances. Extensive case studies with real-world data demonstrate significant savings potentials compared to deterministic models as well as (simplified) stochastic models that already exist in literature