Neuron-level dynamics of oscillatory network structure and markerless tracking of kinematics during grasping

Oscillatory synchrony is proposed to play an important role in flexible sensory-motor transformations. Thereby, it is assumed that changes in the oscillatory network structure at the level of single neurons lead to flexible information processing. Yet, how the oscillatory network structure at the neuron-level changes with different behavior remains elusive. To address this gap, we examined changes in the fronto-parietal oscillatory network structure at the neuron-level, while monkeys performed a flexible sensory-motor grasping task. We found that neurons formed separate subnetworks in the low frequency and beta bands. The beta subnetwork was active during steady states and the low frequency network during active states of the task, suggesting that both frequencies are mutually exclusive at the neuron-level. Furthermore, both frequency subnetworks reconfigured at the neuron-level for different grip and context conditions, which was mostly lost at any scale larger than neurons in the network. Our results, therefore, suggest that the oscillatory network structure at the neuron-level meets the necessary requirements for the coordination of flexible sensory-motor transformations. Supplementarily, tracking hand kinematics is a crucial experimental requirement to analyze neuronal control of grasp movements. To this end, a 3D markerless, gloveless hand tracking system was developed using computer vision and deep learning techniques. 2021-11-3

Ultrafast electron dynamics in molecules within density-matrix-based configuration interaction framework

The main goal of this thesis is to present the results of work concerning photon-induced ultrafast spin dynamics being theoretically modeled within the framework of ab-initio calculations. The effect of chemical structure on the ultrafast spin-flip dynamics in core-excited states of transition metal complexes has been studied. Detailed analysis of spin-orbit coupling-driven dynamics in core-excited states, based on the preselection of states and utilizing the Wigner-Eckart theorem, is conducted. A general framework to numerically simulate the ultrafast electron dynamics was developed

Modeling and Simulation in Engineering

This book provides an open platform to establish and share knowledge developed by scholars, scientists, and engineers from all over the world, about various applications of the modeling and simulation in the design process of products, in various engineering fields. The book consists of 12 chapters arranged in two sections (3D Modeling and Virtual Prototyping), reflecting the multidimensionality of applications related to modeling and simulation. Some of the most recent modeling and simulation techniques, as well as some of the most accurate and sophisticated software in treating complex systems, are applied. All the original contributions in this book are jointed by the basic principle of a successful modeling and simulation process: as complex as necessary, and as simple as possible. The idea is to manipulate the simplifying assumptions in a way that reduces the complexity of the model (in order to make a real-time simulation), but without altering the precision of the results

Model-based operator guidance in interactive, semi-automated production processes

This contribution focuses on the task of guiding and supervision of technical processes realized by human operators. The review of publications of the last decades discloses that especially technical processes with strong interconnection of human operator and manufacturing process are not adequately addressed by the evolved automation approaches. Integrating human process knowledge and experience into the resulting automation system is still a major concern. Besides the introduction of automation in a handcrafting process that is increasing the overall system complexity, the design of the human-machine interface to the automation system is of central importance. Within this thesis, the trade-off between manual manufacturing and automation is addressed by a semi-automation approach. The application example is the no-bake molding process, a mold manufacturing process for casts that is traditionally handmade. Within this process the human operator plays a central role (i.e. knowledge and expertise), whereas the (intelligent) automation is carrying out physical operation, which is guided and supervised by the human operator. This is achieved by experimentally identified quality representing process variables that allow for in-process feedback to the human operator. Process guiding assistance is given using a formalization approach of the human-automation-interaction. By deducing situative information of interest from the resulting human-automation-system model with respect to the current process goal, the established process model is used for supervision and assistance of the overall process. The design of the human-machine-interface is based on a detailed analysis of the handcrafted process and is realized as a direct, intuitively usable, marker-based interaction technique. The integrated human-automation-system and the corresponding human-machine-interface with process guidance assistance functionality is initially evaluated. The results are discussed for the future work with respect to the individual, human operator-specific process understanding and process reproducibility.Diese Arbeit befasst sich mit Fachkraftaufgaben in der Führung und Überwachung von technischen Prozessen. Die Übersicht der Publikationen der letzten Jahrzehnte eröffnet, dass insbesondere technische Prozesse mit enger Verknüpfung von Mensch und Herstellungsprozess bei den entwickelten Automatisierungsansätzen nicht hinreichend berücksichtigt werden. Die Integration von Prozesswissen und -erfahrung in das resultierende Automatisierungssystem bleibt eine offene Fragestellung. Neben der Einführung von Automation in Handarbeitsprozesse, die die Komplexität des Gesamtsystems erhöhen, ist die Gestaltung der Mensch-Maschine-Schnittstelle zum Automatisierungssystem von zentraler Bedeutung. Der Konflikt zwischen Handarbeit und Automatisierung wird in dieser Arbeit durch die Einführung einer Teilautomatisierung gelöst. Das Anwendungsbeispiel ist das Kaltharzverfahren, ein traditionell in Handarbeit bewältigter Herstellungsprozess für Gussformen. In diesem Prozess spielt die Fachkraft eine zentrale Rolle (z. B. durch ihr Prozesswissen und ihre Expertise), während die (intelligente) Automatisierung –geführt und überwacht durch die Fachkraft– anfallende physische Aktionen ausführt. Dies wird durch experimentell ermit- telte qualitäts-beschreibende Prozessgrößen erreicht, die eine in-prozess Rückführung zum Bedienpersonal ermöglichen. Prozessführungsassistenz ist basierend auf die Formalisierung der Mensch-Automation-Interaktion gegeben. Durch die Bestimmung von situativen Informationen hoher Wichtigkeit aus dem resultierenden Mensch-Automation-System Modell bezogen auf das aktuelle Prozessziel, wird das bestehende Prozessmodell zur Überwachung und Prozessführungsassistenz des Gesamtprozesses genutzt. Die Gestaltung der Mensch-Maschine-Schnittstelle basiert auf einer detaillierten Analyse des Handarbeitsprozesses und ist als direkte, intuitiv bedienbare, markerbasierte Interaktionstechnik realisiert. Das integrierte Mensch-Automation-System sowie die zugehörige Mensch-Maschine-Schnittstelle inklusive Prozessführungsassistenzfunktionen wurden initial evaluiert. Die erzielten Ergebnisse werden hinsichtlich des individuellen, fachkraftabhängigen Prozesswissens und der Reproduzierbarkeit für den Ausblick diskutiert

Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance (NMR) spectroscopy is a nondestructive technique that can be used to characterize a wide variety of systems. Sustained development of both methodology and instrumentation have allowed NMR to evolve as a powerful technology, with applications in pure sciences, medicine, drug development, and important branches of industry. NMR provides precise structural information down to each atom and bond in a molecule, and is the only method for the determination of structures of molecules in a solution. This book compiles a series of articles describing the application of NMR in a variety of interesting scientific challenges. The articles illustrate the versatility and flexibility of NMR

(Re)Placing America: Cold War Mapping and the Mediation of International Space

The United States emerged from World War II as an undeniably global power, and as the Cold War unfolded, America faced decisions about where to place and display its power on the globe. The Cold War was a battle between two ideologies and competing world systems, both of which were vying for space and had the tools and technologies to control those spaces. Maps became a central vehicle for the testing of these new boundaries. Mapping projects and programs emerged from a variety of popular cartographers, foreign policy strategists, defense leaders, Congressional representatives, scientists, oppositional movements, labor unions, educational publishers, even everyday citizens. As each of these sources confirms, the scope of American commitments had expanded considerably; to account for this expansion, a cartographic impulse underwrote the continually evolving Cold War, and the tensions of art and science, realism and idealism, and space and place inherent in this impulse helped form the fault lines of the conflict. (Re)Placing America looks largely at the ways that cartography adapted to such changes and tensions in the second half of the twentieth century, and how the United States marshaled the practice of mapping in a variety of ways to account for the shift to internationalism. This dissertation explores how cartography mediated visions of space, and particularly, how it defined America's place within those spaces. Treating cartography as a complex rhetorical process of production, display, and circulation, the five chapters cover major geopolitical thematics, and the responding evolution of maps, from World War II until the Cold War's end in the early 1990s. Some of these driving themes include the "air-age" expansion of visual perspectives and strategic potential in journalistic maps; the appropriation of cartography as a medium for intelligence and national security objectives; the marshaling of maps as evidential weapons against the Soviet Union in diplomatic exchanges, Congressional reports, and government-sponsored propaganda; the shifts from East/West antagonisms to North/South ones as cartography was drafted into the modernization efforts of the U.S. in mapping the Third World; and the Defense Department's use of maps to argue for nuclear deterrence, while protest groups made radical cartographic challenges to these practices of state power. (Re)Placing America reads closely the maps of the forty-years-plus conflict and considers the complexity of their internal codes (in colors, shapes, icons, etc.), while also reaching out externally to the intersecting interests and visions of the cartographic producers and the Cold War contexts in which they emerged. The project seeks out and explores particular nodal points and thematics where maps consolidated and shaped changing shifts in perception, where cartographic fragments cohered around the defining moments, but also sometimes in the everyday politics of the Cold War. Ultimately, this project offers four conclusions about and conduct and operation of American mapping during the complex, ideologically charged time of the Cold War. First, the function of the map to both "fix" and "unfix" particular perceptions of the world is relevant to assessing how America sought to stabilize its place in a rapidly changing world. Second, the internationalism of the Cold War was bound up in the capacities for cartography to document and adapt to it. Third, the humanistic notion of a geographical imagination is central to understanding why particular Cold War agents and institutions continually drew on cartography to represent their interests. Finally, combining an ideological approach to reading maps as articulators of contextual tensions and historical ideas with an instrumental approach to maps as material, strategic documents can best help to situate cartography as an ongoing process of production, circulation, and display

Disruption in the Arts

The volume examines aesthetic disruptions within the various arts in contemporary culture. It assumes that the political potential of art is not solely derived from presenting its audiences with openly political content. Rather, it creates a space of perception and interaction using formal means, thus problematizing the self-evidence of hegemonic structures of communication