The Birth of German Biotechnology Industry: Did Venture Capital run the Show?

The goal of this paper is to point out the role played by private equity investors (venture-capital companies and corporate investors) in the emergence of a new biotechnology industry in Germany in the second half of the 90?s. This analysis takes into account the different business models and business fields to be found in the biotechnology industry. Based on theoretical arguments, a great relevance of VC-companies in financing young innovative biotechnology firms developing health care applications and technology platforms is expected, whereas corporate investors like pharmaceutical and chemical industries should play a more important role in financing supplier companies. Corporate investors are also expected to be significantly present in the equity financing of health care biotechnology companies. Empirical results from descriptive and multivariate analyses confirm all hypotheses but one: surprisingly, corporate investors invested only marginally in the equity funding of biotechnology firms developing new health care products or services. --Start-ups,Biotechnology,Venture Capital,Discrete Choice

The Birth of German Biotechnology Industry – Did Venture Capital run the show?

We answer the questions, how many firms acting in the modern German biotechnology industry are funded by venture capital companies (VCC) as well as equity funded by corporate investors. The theory suggests a high relevance of VCC as venturing partner of high-tech projects. In addition we argue that corporate investors are a venturing partner of firms with high-risk projects to a lower extent.Incumbents,however, are confronted with some opportunities in the low-risk area of the biotechnology industry to secure an optimal supply for the current product pipeline.Our empirical results emphasize a crucial importance of venture capital as financial resource for high-risk projects: whereas 42 percent of all healthcare developer in the early stage are venture-backed firms, only a small share of low-risk projects received venture capital. The results for corporate investors are reversible.Fewer high-tech projects and more low-risk projects compared to VCC are equity financed by corporate investors. The econometric analysis suggests that the observed pattern is mainly driven by the level of project risk and hence, supports all our hypotheses.Biotechnology, Start-ups, Venture Capital, Discrete Choice

New product development in an emerging economy: analysing the role of supplier involvement practices by using Bayesian Markov chain Monte Carlo technique

The research question is whether the positive relationship found between supplier involvement practices and new product development performances in developed economies also holds in emerging economies. The role of supplier involvement practices in new product development performance is yet to be substantially investigated in the emerging economies (other than China). This premise was examined by distributing a survey instrument (Jayaram’s (2008) published survey instrument that has been utilised in developed economies) to Malaysian manufacturing companies. To gauge the relationship between the supplier involvement practices and new product development (NPD) project performance of 146 companies, structural equation modelling was adopted. Our findings prove that supplier involvement practices have a significant positive impact on NPD project performance in an emerging economy with respect to quality objectives, design objectives, cost objectives, and “time-to-market” objectives. Further analysis using the Bayesian Markov Chain Monte Carlo algorithm, yielding a more credible and feasible differentiation, confirmed these results (even in the case of an emerging economy) and indicated that these practices have a 28% impact on variance of NPD project performance. This considerable effect implies that supplier involvement is a must have, although further research is needed to identify the contingencies for its practices

What type of innovative firms acquire knowledge intensive services and from which suppliers?

Knowledge intensive services (KIS) and, in particular, R&D services contribute significantly to innovation in firms. The objective of this paper is to find out which characteristics of firms explain the acquisition of R&D services and to analyse whether there are differences depending on the typology of the supplier (universities, technology centres and consulting firms). Three main conclusions emerge from the econometric estimations. Firstly, the results show that size and age matter in the decision to buy R&D services, but these characteristics of firms do not have any particular influence in the decision to choose a specific supplier. Secondly, our results are consistent with the relevance that the literature gives to human capital in absorbing external knowledge. The variables used to control for human skills have a positive effect on the decision to buy R&D services. On the contrary, the estimates of other variables that capture internal knowledge base suggest that there is a substitution process between internal R&D activities and acquiring R&D services. Thirdly, innovation policy has a significant influence on the decision to acquire R&D services.Knowledge intensive services; R&D services; universities; technology centres; consulting firms; innovation policy

Sustainable supply chain management needs sustainable logistics services. The strategic role played by logistics service providers

Purpose – The purpose of this research is to examine the concept of sustainable service co-creation in triadic business relationships in logistics and supply chain management. More companies seek to develop sustainable solutions that would not be sustainable exclusively for themselves but for the supply chain they belong to. In doing that – especially when dealing with services – they may need the external support from logistics service providers (LSPs). This paper aims to explore the innovative initiatives undertaken by LSPs in triadic relationship management with their customers and suppliers while co-creating sustainable services along the supply chain. Design/methodology/approach – To investigate the research question, a systematic literature review and empirical exploratory investigation through case study will be conducted adopting the qualitative methodology, to explore trends and evolving paradigms. Findings – A literature review conducted in this paper enriches existing literature through an integration of sustainability in a viable system approach and logistics service provision, in particular, it investigates the ways in which sustainability is achieved. It is assumed that the triadic relationship among an LSP and its customers and suppliers requires significant modifications in collaboration and an innovative approach in operating procedures. Research limitations/implications – This paper is an exploratory study and limited in its scope to an example of a relationship that focuses mainly on three actors: the supplier, the LSP and the customer. However, it could be extended in terms of numbers of case studies investigated. Practical implications – The implications arising from the literature and the empirical research offer a range of current sustainable practices in the services sector. This could be a starting point for other research and company activities. Originality/value – There is little research that addresses the issue of sustainability and logistics service providers simultaneously, hence the present paper is meant to fill the gap by providing a foundation which actors of different supply chains could use as a benchmark. This study gives evidence of how logistics services may contribute to sustainable development. Key words – sustainable supply chain management, logistics service providers, viable system approach, co-creation, business relationship managemen

A new perspective on traffic control management using triangular interval type-2 fuzzy sets and interval neutrosophic sets

Controlling traffic flow on roads is an important traffic management task necessary to ensure a peaceful and safe environment for people. The number of cars on roads at any given time is always unknown. Type-2 fuzzy sets and neutrosophic sets play a vital role in dealing efficiently with such uncertainty. In this paper, a triangular interval type-2 Schweizer and Sklar weighted arithmetic (TIT2SSWA) operator and a triangular interval type-2 Schweizer and Sklar weighted geometric (TIT2SSWG) operator based on Schweizer and Sklar triangular norms have been studied, and the validity of these operators has been checked using a numerical example and extended to an interval neutrosophic environment by proposing interval neutrosophic Schweizer and Sklar weighted arithmetic (INSSWA) and interval neutrosophic Schweizer and Sklar weighted geometric (INSSWG) operators. Furthermore, their properties have been examined; some of the more important properties are examined in detail. Moreover, we proposed an improved score function for interval neutrosophic numbers (INNs) to control traffic flow that has been analyzed by identifying the junction that has more vehicles. This improved score function uses score values of triangular interval type-2 fuzzy numbers (TIT2FNs) and interval neutrosophic numbers

Absorptive capacity and relationship learning mechanisms as complementary drivers of green innovation performance

This paper aims to explore in depth how internal and external knowledge-based drivers actually affect the firms\u2019 green innovation performance. Subsequently, this study analyzes the relationships between absorptive capacity (internal knowledge-based driver), relationship learning (external knowledge-based driver) and green innovation performance. This study relies on a sample of 112 firms belonging to the Spanish automotive components manufacturing sector (ACMS) and uses partial least squares path modeling to test the hypotheses proposed. The empirical results show that both absorptive capacity and relationship learning exert a significant positive effect on the dependent variable and that relationship learning moderates the link between absorptive capacity and green innovation performance. This paper presents some limitations with respect to the particular sector (i.e. the ACMS) and geographical context (Spain). For this reason, researchers must be thoughtful while generalizing these results to distinct scenarios. Managers should devote more time and resources to reinforce their absorptive capacity as an important strategic tool to generate new knowledge and hence foster green innovation performance in manufacturing industries. The paper shows the importance of encouraging decision-makers to cultivate and rely on relationship learning mechanisms with their main stakeholders and to acquire the necessary information and knowledge that might be valuable in the maturity of green innovations. This study proposes that relationship learning plays a moderating role in the relationship between absorptive capacity and green innovation performance