Supervised Learning Models for the Preliminary Detection of COVID-19 in Patients Using Demographic and Epidemiological Parameters

The World Health Organization labelled the new COVID-19 breakout a public health crisis of worldwide concern on 30 January 2020, and it was named the new global pandemic in March 2020. It has had catastrophic consequences on the world economy and well-being of people and has put a tremendous strain on already-scarce healthcare systems globally, particularly in underdeveloped countries. Over 11 billion vaccine doses have already been administered worldwide, and the benefits of these vaccinations will take some time to appear. Today, the only practical approach to diagnosing COVID-19 is through the RT-PCR and RAT tests, which have sometimes been known to give unreliable results. Timely diagnosis and implementation of precautionary measures will likely improve the survival outcome and decrease the fatality rates. In this study, we propose an innovative way to predict COVID-19 with the help of alternative non-clinical methods such as supervised machine learning models to identify the patients at risk based on their characteristic parameters and underlying comorbidities. Medical records of patients from Mexico admitted between 23 January 2020 and 26 March 2022, were chosen for this purpose. Among several supervised machine learning approaches tested, the XGBoost model achieved the best results with an accuracy of 92%. It is an easy, non-invasive, inexpensive, instant and accurate way of forecasting those at risk of contracting the virus. However, it is pretty early to deduce that this method can be used as an alternative in the clinical diagnosis of coronavirus cases

Development and evaluation of machine learning algorithms for biomedical applications

Gene network inference and drug response prediction are two important problems in computational biomedicine. The former helps scientists better understand the functional elements and regulatory circuits of cells. The latter helps a physician gain full understanding of the effective treatment on patients. Both problems have been widely studied, though current solutions are far from perfect. More research is needed to improve the accuracy of existing approaches. This dissertation develops machine learning and data mining algorithms, and applies these algorithms to solve the two important biomedical problems. Specifically, to tackle the gene network inference problem, the dissertation proposes (i) new techniques for selecting topological features suitable for link prediction in gene networks; a graph sparsification method for network sampling; (iii) combined supervised and unsupervised methods to infer gene networks; and (iv) sampling and boosting techniques for reverse engineering gene networks. For drug sensitivity prediction problem, the dissertation presents (i) an instance selection technique and hybrid method for drug sensitivity prediction; (ii) a link prediction approach to drug sensitivity prediction; a noise-filtering method for drug sensitivity prediction; and (iv) transfer learning approaches for enhancing the performance of drug sensitivity prediction. Substantial experiments are conducted to evaluate the effectiveness and efficiency of the proposed algorithms. Experimental results demonstrate the feasibility of the algorithms and their superiority over the existing approaches

Applications

Volume 3 describes how resource-aware machine learning methods and techniques are used to successfully solve real-world problems. The book provides numerous specific application examples: in health and medicine for risk modelling, diagnosis, and treatment selection for diseases in electronics, steel production and milling for quality control during manufacturing processes in traffic, logistics for smart cities and for mobile communications

Applications

Volume 3 describes how resource-aware machine learning methods and techniques are used to successfully solve real-world problems. The book provides numerous specific application examples: in health and medicine for risk modelling, diagnosis, and treatment selection for diseases in electronics, steel production and milling for quality control during manufacturing processes in traffic, logistics for smart cities and for mobile communications

Computational Methods for the Analysis of Genomic Data and Biological Processes

In recent decades, new technologies have made remarkable progress in helping to understand biological systems. Rapid advances in genomic profiling techniques such as microarrays or high-performance sequencing have brought new opportunities and challenges in the fields of computational biology and bioinformatics. Such genetic sequencing techniques allow large amounts of data to be produced, whose analysis and cross-integration could provide a complete view of organisms. As a result, it is necessary to develop new techniques and algorithms that carry out an analysis of these data with reliability and efficiency. This Special Issue collected the latest advances in the field of computational methods for the analysis of gene expression data, and, in particular, the modeling of biological processes. Here we present eleven works selected to be published in this Special Issue due to their interest, quality, and originality

Personalized Medicine in Epidemics

This reprint contains 11 chapters on a wide range of subjects related to the impacts of different types of epidemics on our ability to practice personalized medicine. Together, these chapters provide a broad overview with many different examples of epidemics. The personalization of medicine is present both despite and because of epidemics. Many more examples are possible, but this reprint offers a primary overview emphasizing the widely spread relevance of the topic

WOFEX 2021 : 19th annual workshop, Ostrava, 1th September 2021 : proceedings of papers

The workshop WOFEX 2021 (PhD workshop of Faculty of Electrical Engineer-ing and Computer Science) was held on September 1st September 2021 at the VSB – Technical University of Ostrava. The workshop offers an opportunity for students to meet and share their research experiences, to discover commonalities in research and studentship, and to foster a collaborative environment for joint problem solving. PhD students are encouraged to attend in order to ensure a broad, unconfined discussion. In that view, this workshop is intended for students and researchers of this faculty offering opportunities to meet new colleagues.Ostrav