Neuromuscular disease classification system

Diagnosis of neuromuscular diseases is based on subjective visual assessment of biopsies from patients by the pathologist specialist. A system for objective analysis and classification of muscular dystrophies and neurogenic atrophies through muscle biopsy images of fluorescence microscopy is presented. The procedure starts with an accurate segmentation of the muscle fibers using mathematical morphology and a watershed transform. A feature extraction step is carried out in two parts: 24 features that pathologists take into account to diagnose the diseases and 58 structural features that the human eye cannot see, based on the assumption that the biopsy is considered as a graph, where the nodes are represented by each fiber, and two nodes are connected if two fibers are adjacent. A feature selection using sequential forward selection and sequential backward selection methods, a classification using a Fuzzy ARTMAP neural network, and a study of grading the severity are performed on these two sets of features. A database consisting of 91 images was used: 71 images for the training step and 20 as the test. A classification error of 0% was obtained. It is concluded that the addition of features undetectable by the human visual inspection improves the categorization of atrophic pattern

Automated construction of a hierarchy of self-organized neural network classifiers

This paper documents an effort to design and implement a neural network-based, automatic classification system which dynamically constructs and trains a decision tree. The system is a combination of neural network and decision tree technology. The decision tree is constructed to partition a large classification problem into smaller problems. The neural network modules then solve these smaller problems. We used a variant of the Fuzzy ARTMAP neural network which can be trained much more quickly than traditional neural networks. The research extends the concept of self-organization from within the neural network to the overall structure of the dynamically constructed decision hierarchy. The primary advantage is avoidance of manual tedium and subjective bias in constructing decision hierarchies. Additionally, removing the need for manual construction of the hierarchy opens up a large class of potential classification applications. When tested on data from real-world images, the automatically generated hierarchies performed slightly better than an intuitive (handbuilt) hierarchy. Because the neural networks at the nodes of the decision hierarchy are solving smaller problems, generalization performance can really be improved if the number of features used to solve these problems is reduced. Algorithms for automatically selecting which features to use for each individual classification module were also implemented. We were able to achieve the same level of performance as in previous manual efforts, but in an efficient, automatic manner. The technology developed has great potential in a number of commercial areas, including data mining, pattern recognition, and intelligent interfaces for personal computer applications. Sample applications include: fraud detection, bankruptcy prediction, data mining agent, scalable object recognition system, email agent, resource librarian agent, and a decision aid agent

A survey on utilization of data mining approaches for dermatological (skin) diseases prediction

Due to recent technology advances, large volumes of medical data is obtained. These data contain valuable information. Therefore data mining techniques can be used to extract useful patterns. This paper is intended to introduce data mining and its various techniques and a survey of the available literature on medical data mining. We emphasize mainly on the application of data mining on skin diseases. A categorization has been provided based on the different data mining techniques. The utility of the various data mining methodologies is highlighted. Generally association mining is suitable for extracting rules. It has been used especially in cancer diagnosis. Classification is a robust method in medical mining. In this paper, we have summarized the different uses of classification in dermatology. It is one of the most important methods for diagnosis of erythemato-squamous diseases. There are different methods like Neural Networks, Genetic Algorithms and fuzzy classifiaction in this topic. Clustering is a useful method in medical images mining. The purpose of clustering techniques is to find a structure for the given data by finding similarities between data according to data characteristics. Clustering has some applications in dermatology. Besides introducing different mining methods, we have investigated some challenges which exist in mining skin data

A Review of Fault Diagnosing Methods in Power Transmission Systems

Transient stability is important in power systems. Disturbances like faults need to be segregated to restore transient stability. A comprehensive review of fault diagnosing methods in the power transmission system is presented in this paper. Typically, voltage and current samples are deployed for analysis. Three tasks/topics; fault detection, classification, and location are presented separately to convey a more logical and comprehensive understanding of the concepts. Feature extractions, transformations with dimensionality reduction methods are discussed. Fault classification and location techniques largely use artificial intelligence (AI) and signal processing methods. After the discussion of overall methods and concepts, advancements and future aspects are discussed. Generalized strengths and weaknesses of different AI and machine learning-based algorithms are assessed. A comparison of different fault detection, classification, and location methods is also presented considering features, inputs, complexity, system used and results. This paper may serve as a guideline for the researchers to understand different methods and techniques in this field

Modular feature selection using relative importance factors

Feature selection plays an important role in finding relevant or irrelevant features in classification. Genetic algorithms (GAs) have been used as conventional methods for classifiers to adaptively evolve solutions for classification problems. In this paper, we explore the use of feature selection in modular GA-based classification. We propose a new feature selection technique, Relative Importance Factor (RIF), to find irrelevant features in the feature space of each module. By removing these features, we aim to improve classification accuracy and reduce the dimensionality of classification problems. Benchmark classification data sets are used to evaluate the proposed approaches. The experiment results show that RIF can be used to determine irrelevant features and help achieve higher classification accuracy with the feature space dimension reduced. The complexity of the resulting rule sets is also reduced which means the modular classifiers with irrelevant features removed will be able to classify data with a higher throughput

Adaptive Resonance Theory: Self-Organizing Networks for Stable Learning, Recognition, and Prediction

Adaptive Resonance Theory (ART) is a neural theory of human and primate information processing and of adaptive pattern recognition and prediction for technology. Biological applications to attentive learning of visual recognition categories by inferotemporal cortex and hippocampal system, medial temporal amnesia, corticogeniculate synchronization, auditory streaming, speech recognition, and eye movement control are noted. ARTMAP systems for technology integrate neural networks, fuzzy logic, and expert production systems to carry out both unsupervised and supervised learning. Fast and slow learning are both stable response to large non stationary databases. Match tracking search conjointly maximizes learned compression while minimizing predictive error. Spatial and temporal evidence accumulation improve accuracy in 3-D object recognition. Other applications are noted.Office of Naval Research (N00014-95-I-0657, N00014-95-1-0409, N00014-92-J-1309, N00014-92-J4015); National Science Foundation (IRI-94-1659