5,216 research outputs found
Deep transfer learning for improving single-EEG arousal detection
Datasets in sleep science present challenges for machine learning algorithms
due to differences in recording setups across clinics. We investigate two deep
transfer learning strategies for overcoming the channel mismatch problem for
cases where two datasets do not contain exactly the same setup leading to
degraded performance in single-EEG models. Specifically, we train a baseline
model on multivariate polysomnography data and subsequently replace the first
two layers to prepare the architecture for single-channel
electroencephalography data. Using a fine-tuning strategy, our model yields
similar performance to the baseline model (F1=0.682 and F1=0.694,
respectively), and was significantly better than a comparable single-channel
model. Our results are promising for researchers working with small databases
who wish to use deep learning models pre-trained on larger databases.Comment: Accepted for presentation at EMBC202
Towards a Flexible Deep Learning Method for Automatic Detection of Clinically Relevant Multi-Modal Events in the Polysomnogram
Much attention has been given to automatic sleep staging algorithms in past
years, but the detection of discrete events in sleep studies is also crucial
for precise characterization of sleep patterns and possible diagnosis of sleep
disorders. We propose here a deep learning model for automatic detection and
annotation of arousals and leg movements. Both of these are commonly seen
during normal sleep, while an excessive amount of either is linked to disrupted
sleep patterns, excessive daytime sleepiness impacting quality of life, and
various sleep disorders. Our model was trained on 1,485 subjects and tested on
1,000 separate recordings of sleep. We tested two different experimental setups
and found optimal arousal detection was attained by including a recurrent
neural network module in our default model with a dynamic default event window
(F1 = 0.75), while optimal leg movement detection was attained using a static
event window (F1 = 0.65). Our work show promise while still allowing for
improvements. Specifically, future research will explore the proposed model as
a general-purpose sleep analysis model.Comment: Accepted for publication in 41st International Engineering in
Medicine and Biology Conference (EMBC), July 23-27, 201
RED: Deep Recurrent Neural Networks for Sleep EEG Event Detection
The brain electrical activity presents several short events during sleep that
can be observed as distinctive micro-structures in the electroencephalogram
(EEG), such as sleep spindles and K-complexes. These events have been
associated with biological processes and neurological disorders, making them a
research topic in sleep medicine. However, manual detection limits their study
because it is time-consuming and affected by significant inter-expert
variability, motivating automatic approaches. We propose a deep learning
approach based on convolutional and recurrent neural networks for sleep EEG
event detection called Recurrent Event Detector (RED). RED uses one of two
input representations: a) the time-domain EEG signal, or b) a complex
spectrogram of the signal obtained with the Continuous Wavelet Transform (CWT).
Unlike previous approaches, a fixed time window is avoided and temporal context
is integrated to better emulate the visual criteria of experts. When evaluated
on the MASS dataset, our detectors outperform the state of the art in both
sleep spindle and K-complex detection with a mean F1-score of at least 80.9%
and 82.6%, respectively. Although the CWT-domain model obtained a similar
performance than its time-domain counterpart, the former allows in principle a
more interpretable input representation due to the use of a spectrogram. The
proposed approach is event-agnostic and can be used directly to detect other
types of sleep events.Comment: 8 pages, 5 figures. In proceedings of the 2020 International Joint
Conference on Neural Networks (IJCNN 2020
Detection of REM Sleep Behaviour Disorder by Automated Polysomnography Analysis
Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is
an early predictor of Parkinson's disease. This study proposes a
fully-automated framework for RBD detection consisting of automated sleep
staging followed by RBD identification. Analysis was assessed using a limited
polysomnography montage from 53 participants with RBD and 53 age-matched
healthy controls. Sleep stage classification was achieved using a Random Forest
(RF) classifier and 156 features extracted from electroencephalogram (EEG),
electrooculogram (EOG) and electromyogram (EMG) channels. For RBD detection, a
RF classifier was trained combining established techniques to quantify muscle
atonia with additional features that incorporate sleep architecture and the EMG
fractal exponent. Automated multi-state sleep staging achieved a 0.62 Cohen's
Kappa score. RBD detection accuracy improved by 10% to 96% (compared to
individual established metrics) when using manually annotated sleep staging.
Accuracy remained high (92%) when using automated sleep staging. This study
outperforms established metrics and demonstrates that incorporating sleep
architecture and sleep stage transitions can benefit RBD detection. This study
also achieved automated sleep staging with a level of accuracy comparable to
manual annotation. This study validates a tractable, fully-automated, and
sensitive pipeline for RBD identification that could be translated to wearable
take-home technology.Comment: 20 pages, 3 figure
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