517 research outputs found

    Development and application of a platform for harmonisation and integration of metabolomics data

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    Integrating diverse metabolomics data for molecular epidemiology analyses provides both opportuni- ties and challenges in the field of human health research. Combining patient cohorts may improve power and sensitivity of analyses but is challenging due to significant technical and analytical vari- ability. Additionally, current systems for the storage and analysis of metabolomics data suffer from scalability, query-ability, and integration issues that limit their adoption for molecular epidemiological research. Here, a novel platform for integrative metabolomics is developed, which addresses issues of storage, harmonisation, querying, scaling, and analysis of large-scale metabolomics data. Its use is demonstrated through an investigation of molecular trends of ageing in an integrated four-cohort dataset where the advantages and disadvantages of combining balanced and unbalanced cohorts are explored, and robust metabolite trends are successfully identified and shown to be concordant with previous studies.Open Acces

    Machine Learning Algorithm for the Scansion of Old Saxon Poetry

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    Several scholars designed tools to perform the automatic scansion of poetry in many languages, but none of these tools deal with Old Saxon or Old English. This project aims to be a first attempt to create a tool for these languages. We implemented a Bidirectional Long Short-Term Memory (BiLSTM) model to perform the automatic scansion of Old Saxon and Old English poems. Since this model uses supervised learning, we manually annotated the Heliand manuscript, and we used the resulting corpus as labeled dataset to train the model. The evaluation of the performance of the algorithm reached a 97% for the accuracy and a 99% of weighted average for precision, recall and F1 Score. In addition, we tested the model with some verses from the Old Saxon Genesis and some from The Battle of Brunanburh, and we observed that the model predicted almost all Old Saxon metrical patterns correctly misclassified the majority of the Old English input verses

    Envisioning Transitions. Bodies, buildings, and boundaries

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    “Transition” is the dynamic process of changing state, going beyond, crossing over, and passing from one point to the next. The signification of the word is close to that of evolution, modification, mutation, and transformation, all of which are confined into a strictly restricted timeframe. Etymologically, “transitions” can be nothing else than temporary: they appear silently, burst, violently establish, and gradually disappear into reality. In their blinding momentariness, “transitions” bear with them the positive undertone of change and renewal, along with the hopefulness of that which is unknown.  If the term “transition” recurs regularly in the contemporary vocabulary of architecture and design cultures, this repetition reveals a period characterized by overlapping and sequential changes. The word is without a doubt overused, but not without reason. Indeed, we find ourselves in an unusually extended period of consecutive “transitions”, overwhelmingly undefined in temporality and ambitions. As we are witnessing societies go through stark demographic, political, economic, and cultural changes, the intersecting problematics (e.g., ecological, digital, pandemic, etc.) form a rather complex topography of change, negatively charged by the instability of dilated time and the uncertainty of undefined destination. The word is employed with the confidence of a natural process, as if it were a storm, and while we affirm our existence in “transition”, we nod our troubled times away. Whether positively or negatively perceived, “transitions” form bridges between histories. Yet, what does it actually mean to be in “transition”? Can we define it as an autonomous and productive period whose importance could go beyond a starting and an ending date? How are “transitions” impacting and being impacted by human spaces, the built environment, and design cultures? What are some concrete, practical case studies that demonstrate how “transitions” could affect architecture and design cultures while emphasizing the role that these disciplines play in transitional processes? It is within this backdrop that we put forward the theme of “transition”—in all its simplicity and complexity

    The web-based simulation and information service for multi-hazard impact chains. Design document.

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    The overall objective of the PARATUS project and the platform is the co-development of a web-based simulation and information service for first and second responders and other stakeholders to evaluate the impact chains of multi-hazard events with particular emphasis on cross-border and cascading impacts. This deliverable provides a first impression of the platform and its components. A central theme in the PARATUS project is the co-development of the tools with stakeholders. The central stakeholders within the four applications case studies are therefore full project partners. They will be directly involved in the development of the platform. We foresee that the PARATUS Platform will have two major blocks: an information service that provides static information (or regularly updated information) and simulation service, which is a dynamic component where stakeholders can interactively work with the tools in the platform. The PARATUS will further make sure that documentation (e.g., software accompanying documentation) is also publicly available via the project website1 and other trusted repositories. The deliverable 4.1 was submitted to the European Commission on 31/07/2023 and is waiting for approval by the Research Executive Agency. Therefore, this current version may not represent the final version of the deliverable

    Integration of heterogeneous data sources and automated reasoning in healthcare and domotic IoT systems

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    In recent years, IoT technology has radically transformed many crucial industrial and service sectors such as healthcare. The multi-facets heterogeneity of the devices and the collected information provides important opportunities to develop innovative systems and services. However, the ubiquitous presence of data silos and the poor semantic interoperability in the IoT landscape constitute a significant obstacle in the pursuit of this goal. Moreover, achieving actionable knowledge from the collected data requires IoT information sources to be analysed using appropriate artificial intelligence techniques such as automated reasoning. In this thesis work, Semantic Web technologies have been investigated as an approach to address both the data integration and reasoning aspect in modern IoT systems. In particular, the contributions presented in this thesis are the following: (1) the IoT Fitness Ontology, an OWL ontology that has been developed in order to overcome the issue of data silos and enable semantic interoperability in the IoT fitness domain; (2) a Linked Open Data web portal for collecting and sharing IoT health datasets with the research community; (3) a novel methodology for embedding knowledge in rule-defined IoT smart home scenarios; and (4) a knowledge-based IoT home automation system that supports a seamless integration of heterogeneous devices and data sources

    On Making in the Digital Humanities

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    On Making in the Digital Humanities fills a gap in our understanding of digital humanities projects and craft by exploring the processes of making as much as the products that arise from it. The volume draws focus to the interwoven layers of human and technological textures that constitute digital humanities scholarship. To do this, it assembles a group of well-known, experienced and emerging scholars in the digital humanities to reflect on various forms of making (we privilege here the creative and applied side of the digital humanities). The volume honours the work of John Bradley, as it is totemic of a practice of making that is deeply informed by critical perspectives. A special chapter also honours the profound contributions that this volume’s co-editor, Stéfan Sinclair, made to the creative, applied and intellectual praxis of making and the digital humanities. Stéfan Sinclair passed away on 6 August 2020. The chapters gathered here are individually important, but together provide a very human view on what it is to do the digital humanities, in the past, present and future. This book will accordingly be of interest to researchers, teachers and students of the digital humanities; creative humanities, including maker spaces and culture; information studies; the history of computing and technology; and the history of science and the humanities

    LIPIcs, Volume 277, GIScience 2023, Complete Volume

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    LIPIcs, Volume 277, GIScience 2023, Complete Volum

    A Modern Approach to Visualise Structured and Unstructured Space Missions' Data

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    In this paper the Visualisation and Data Analysis (ViDA) project, currently being developed at the German Space Operations Center (GSOC), is presented. ViDA is a modern, interactive, web-based frontend tool designed to efficiently explore various types of data generated by space missions. It is more than just a telemetry display tool and, as such, includes features from business intelligence, data science and AI tools, while being focused on the multi-spacecraft operations use case. The paper describes how the big data challenges (volume, variety, variability, complexity, value) in the context of spacecraft operations have been addressed and how the adopted solutions have been integrated into ViDA. It also highlights the importance of contextual knowledge as crucial point for the design and implementation of ViDA. The techniques used for creating appropriate visual representations of the data and their relations are described. Such visualisations are specifically designed to deliver interpretable results to the users, thus helping them to quickly extract knowledge from them during their analytical process. Finally, the integration of ViDA into the ground system and its connections to the other tools in the telemetry/telecommand chain are discussed
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