Automatic region-of-interest extraction in low depth-of-field images

PhD ThesisAutomatic extraction of focused regions from images with low depth-of-field (DOF) is a problem without an efficient solution yet. The capability of extracting focused regions can help to bridge the semantic gap by integrating image regions which are meaningfully relevant and generally do not exhibit uniform visual characteristics. There exist two main difficulties for extracting focused regions from low DOF images using high-frequency based techniques: computational complexity and performance. A novel unsupervised segmentation approach based on ensemble clustering is proposed to extract the focused regions from low DOF images in two stages. The first stage is to cluster image blocks in a joint contrast-energy feature space into three constituent groups. To achieve this, we make use of a normal mixture-based model along with standard expectation-maximization (EM) algorithm at two consecutive levels of block size. To avoid the common problem of local optima experienced in many models, an ensemble EM clustering algorithm is proposed. As a result, relevant blocks, i.e., block-based region-of-interest (ROI), closely conforming to image objects are extracted. In stage two, two different approaches have been developed to extract pixel-based ROI. In the first approach, a binary saliency map is constructed from the relevant blocks at the pixel level, which is based on difference of Gaussian (DOG) and binarization methods. Then, a set of morphological operations is employed to create the pixel-based ROI from the map. Experimental results demonstrate that the proposed approach achieves an average segmentation performance of 91.3% and is computationally 3 times faster than the best existing approach. In the second approach, a minimal graph cut is constructed by using the max-flow method and also by using object/background seeds provided by the ensemble clustering algorithm. Experimental results demonstrate an average segmentation performance of 91.7% and approximately 50% reduction of the average computational time by the proposed colour based approach compared with existing unsupervised approaches

Solving Inverse Problems with Piecewise Linear Estimators: From Gaussian Mixture Models to Structured Sparsity

A general framework for solving image inverse problems is introduced in this paper. The approach is based on Gaussian mixture models, estimated via a computationally efficient MAP-EM algorithm. A dual mathematical interpretation of the proposed framework with structured sparse estimation is described, which shows that the resulting piecewise linear estimate stabilizes the estimation when compared to traditional sparse inverse problem techniques. This interpretation also suggests an effective dictionary motivated initialization for the MAP-EM algorithm. We demonstrate that in a number of image inverse problems, including inpainting, zooming, and deblurring, the same algorithm produces either equal, often significantly better, or very small margin worse results than the best published ones, at a lower computational cost.Comment: 30 page

An attention model and its application in man-made scene interpretation

The ultimate aim of research into computer vision is designing a system which interprets its surrounding environment in a similar way the human can do effortlessly. However, the state of technology is far from achieving such a goal. In this thesis different components of a computer vision system that are designed for the task of interpreting man-made scenes, in particular images of buildings, are described. The flow of information in the proposed system is bottom-up i.e., the image is first segmented into its meaningful components and subsequently the regions are labelled using a contextual classifier. Starting from simple observations concerning the human vision system and the gestalt laws of human perception, like the law of “good (simple) shape” and “perceptual grouping”, a blob detector is developed, that identifies components in a 2D image. These components are convex regions of interest, with interest being defined as significant gradient magnitude content. An eye tracking experiment is conducted, which shows that the regions identified by the blob detector, correlate significantly with the regions which drive the attention of viewers. Having identified these blobs, it is postulated that a blob represents an object, linguistically identified with its own semantic name. In other words, a blob may contain a window a door or a chimney in a building. These regions are used to identify and segment higher order structures in a building, like facade, window array and also environmental regions like sky and ground. Because of inconsistency in the unary features of buildings, a contextual learning algorithm is used to classify the segmented regions. A model which learns spatial and topological relationships between different objects from a set of hand-labelled data, is used. This model utilises this information in a MRF to achieve consistent labellings of new scenes

Computerized Analysis of Magnetic Resonance Images to Study Cerebral Anatomy in Developing Neonates

The study of cerebral anatomy in developing neonates is of great importance for the understanding of brain development during the early period of life. This dissertation therefore focuses on three challenges in the modelling of cerebral anatomy in neonates during brain development. The methods that have been developed all use Magnetic Resonance Images (MRI) as source data. To facilitate study of vascular development in the neonatal period, a set of image analysis algorithms are developed to automatically extract and model cerebral vessel trees. The whole process consists of cerebral vessel tracking from automatically placed seed points, vessel tree generation, and vasculature registration and matching. These algorithms have been tested on clinical Time-of- Flight (TOF) MR angiographic datasets. To facilitate study of the neonatal cortex a complete cerebral cortex segmentation and reconstruction pipeline has been developed. Segmentation of the neonatal cortex is not effectively done by existing algorithms designed for the adult brain because the contrast between grey and white matter is reversed. This causes pixels containing tissue mixtures to be incorrectly labelled by conventional methods. The neonatal cortical segmentation method that has been developed is based on a novel expectation-maximization (EM) method with explicit correction for mislabelled partial volume voxels. Based on the resulting cortical segmentation, an implicit surface evolution technique is adopted for the reconstruction of the cortex in neonates. The performance of the method is investigated by performing a detailed landmark study. To facilitate study of cortical development, a cortical surface registration algorithm for aligning the cortical surface is developed. The method first inflates extracted cortical surfaces and then performs a non-rigid surface registration using free-form deformations (FFDs) to remove residual alignment. Validation experiments using data labelled by an expert observer demonstrate that the method can capture local changes and follow the growth of specific sulcus

Using multiple classifiers for predicting the risk of endovascular aortic aneurysm repair re-intervention through hybrid feature selection.

Feature selection is essential in medical area; however, its process becomes complicated with the presence of censoring which is the unique character of survival analysis. Most survival feature selection methods are based on Cox's proportional hazard model, though machine learning classifiers are preferred. They are less employed in survival analysis due to censoring which prevents them from directly being used to survival data. Among the few work that employed machine learning classifiers, partial logistic artificial neural network with auto-relevance determination is a well-known method that deals with censoring and perform feature selection for survival data. However, it depends on data replication to handle censoring which leads to unbalanced and biased prediction results especially in highly censored data. Other methods cannot deal with high censoring. Therefore, in this article, a new hybrid feature selection method is proposed which presents a solution to high level censoring. It combines support vector machine, neural network, and K-nearest neighbor classifiers using simple majority voting and a new weighted majority voting method based on survival metric to construct a multiple classifier system. The new hybrid feature selection process uses multiple classifier system as a wrapper method and merges it with iterated feature ranking filter method to further reduce features. Two endovascular aortic repair datasets containing 91% censored patients collected from two centers were used to construct a multicenter study to evaluate the performance of the proposed approach. The results showed the proposed technique outperformed individual classifiers and variable selection methods based on Cox's model such as Akaike and Bayesian information criterions and least absolute shrinkage and selector operator in p values of the log-rank test, sensitivity, and concordance index. This indicates that the proposed classifier is more powerful in correctly predicting the risk of re-intervention enabling doctor in selecting patients' future follow-up plan