10,676 research outputs found

    Innovative in silico approaches to address avian flu using grid technology

    Get PDF
    The recent years have seen the emergence of diseases which have spread very quickly all around the world either through human travels like SARS or animal migration like avian flu. Among the biggest challenges raised by infectious emerging diseases, one is related to the constant mutation of the viruses which turns them into continuously moving targets for drug and vaccine discovery. Another challenge is related to the early detection and surveillance of the diseases as new cases can appear just anywhere due to the globalization of exchanges and the circulation of people and animals around the earth, as recently demonstrated by the avian flu epidemics. For 3 years now, a collaboration of teams in Europe and Asia has been exploring some innovative in silico approaches to better tackle avian flu taking advantage of the very large computing resources available on international grid infrastructures. Grids were used to study the impact of mutations on the effectiveness of existing drugs against H5N1 and to find potentially new leads active on mutated strains. Grids allow also the integration of distributed data in a completely secured way. The paper presents how we are currently exploring how to integrate the existing data sources towards a global surveillance network for molecular epidemiology.Comment: 7 pages, submitted to Infectious Disorders - Drug Target

    Soft-Defined Heterogeneous Vehicular Network: Architecture and Challenges

    Full text link
    Heterogeneous Vehicular NETworks (HetVNETs) can meet various quality-of-service (QoS) requirements for intelligent transport system (ITS) services by integrating different access networks coherently. However, the current network architecture for HetVNET cannot efficiently deal with the increasing demands of rapidly changing network landscape. Thanks to the centralization and flexibility of the cloud radio access network (Cloud-RAN), soft-defined networking (SDN) can conveniently be applied to support the dynamic nature of future HetVNET functions and various applications while reducing the operating costs. In this paper, we first propose the multi-layer Cloud RAN architecture for implementing the new network, where the multi-domain resources can be exploited as needed for vehicle users. Then, the high-level design of soft-defined HetVNET is presented in detail. Finally, we briefly discuss key challenges and solutions for this new network, corroborating its feasibility in the emerging fifth-generation (5G) era

    Architectures for smart end-user services in the power grid

    Get PDF
    Abstract-The increase of distributed renewable electricity generators, such as solar cells and wind turbines, requires a new energy management system. These distributed generators introduce bidirectional energy flows in the low-voltage power grid, requiring novel coordination mechanisms to balance local supply and demand. Closed solutions exist for energy management on the level of individual homes. However, no service architectures have been defined that allow the growing number of end-users to interact with the other power consumers and generators and to get involved in more rational energy consumption patterns using intuitive applications. We therefore present a common service architecture that allows houses with renewable energy generation and smart energy devices to plug into a distributed energy management system, integrated with the public power grid. Next to the technical details, we focus on the usability aspects of the end-user applications in order to contribute to high service adoption and optimal user involvement. The presented architecture facilitates end-users to reduce net energy consumption, enables power grid providers to better balance supply and demand, and allows new actors to join with new services. We present a novel simulator that allows to evaluate both the power grid and data communication aspects, and illustrate a 22% reduction of the peak load by deploying a central coordinator inside the home gateway of an end-user

    ERIGrid Holistic Test Description for Validating Cyber-Physical Energy Systems

    Get PDF
    Smart energy solutions aim to modify and optimise the operation of existing energy infrastructure. Such cyber-physical technology must be mature before deployment to the actual infrastructure, and competitive solutions will have to be compliant to standards still under development. Achieving this technology readiness and harmonisation requires reproducible experiments and appropriately realistic testing environments. Such testbeds for multi-domain cyber-physical experiments are complex in and of themselves. This work addresses a method for the scoping and design of experiments where both testbed and solution each require detailed expertise. This empirical work first revisited present test description approaches, developed a newdescription method for cyber-physical energy systems testing, and matured it by means of user involvement. The new Holistic Test Description (HTD) method facilitates the conception, deconstruction and reproduction of complex experimental designs in the domains of cyber-physical energy systems. This work develops the background and motivation, offers a guideline and examples to the proposed approach, and summarises experience from three years of its application.This work received funding in the European Community’s Horizon 2020 Program (H2020/2014–2020) under project “ERIGrid” (Grant Agreement No. 654113)

    Laboratory coupling approach

    Get PDF
    This chapter deals with the coupling of smart grid laboratories for joint experiments. Therefore, various possibilities are outlined and a reference implementation is introduced. Finally, the vision of a distributed, virtual research infrastructure is presented

    Service Orientation and the Smart Grid state and trends

    Get PDF
    The energy market is undergoing major changes, the most notable of which is the transition from a hierarchical closed system toward a more open one highly based on a “smart” information-rich infrastructure. This transition calls for new information and communication technologies infrastructures and standards to support it. In this paper, we review the current state of affairs and the actual technologies with respect to such transition. Additionally, we highlight the contact points between the needs of the future grid and the advantages brought by service-oriented architectures.
    • 

    corecore