A variational approach to the registration of tensor-valued images

We present a variational framework for the registration of tensor valued images. It is based on an energy functional with four terms: a data term based on a diffusion tensor constancy constraint, a compatibility term encoding the physical model linking domain deformations and tensor reorientation, and smoothness terms for deformation and tensor reorientation. Although the tensor deformation model employed here is designed with regard to diffusion tensor MRI data, the separation of data and compatibility term allows to adapt the model easily to different tensor deformation models. We minimise the energy functional with respect to both transformation fields by a multiscale gradient descent. Experiments demonstrate the viability and potential of this approach in the registration of tensor-valued images

A variational approach to the registration of tensor-valued images

We present a variational framework for the registration of tensor valued images. It is based on an energy functional with four terms: a data term based on a diffusion tensor constancy constraint, a compatibility term encoding the physical model linking domain deformations and tensor reorientation, and smoothness terms for deformation and tensor reorientation. Although the tensor deformation model employed here is designed with regard to diffusion tensor MRI data, the separation of data and compatibility term allows to adapt the model easily to different tensor deformation models. We minimise the energy functional with respect to both transformation fields by a multiscale gradient descent. Experiments demonstrate the viability and potential of this approach in the registration of tensor-valued images

Indirect Image Registration with Large Diffeomorphic Deformations

The paper adapts the large deformation diffeomorphic metric mapping framework for image registration to the indirect setting where a template is registered against a target that is given through indirect noisy observations. The registration uses diffeomorphisms that transform the template through a (group) action. These diffeomorphisms are generated by solving a flow equation that is defined by a velocity field with certain regularity. The theoretical analysis includes a proof that indirect image registration has solutions (existence) that are stable and that converge as the data error tends so zero, so it becomes a well-defined regularization method. The paper concludes with examples of indirect image registration in 2D tomography with very sparse and/or highly noisy data.Comment: 43 pages, 4 figures, 1 table; revise

Diffeomorphic Metric Mapping and Probabilistic Atlas Generation of Hybrid Diffusion Imaging based on BFOR Signal Basis

We propose a large deformation diffeomorphic metric mapping algorithm to align multiple b-value diffusion weighted imaging (mDWI) data, specifically acquired via hybrid diffusion imaging (HYDI), denoted as LDDMM-HYDI. We then propose a Bayesian model for estimating the white matter atlas from HYDIs. We adopt the work given in Hosseinbor et al. (2012) and represent the q-space diffusion signal with the Bessel Fourier orientation reconstruction (BFOR) signal basis. The BFOR framework provides the representation of mDWI in the q-space and thus reduces memory requirement. In addition, since the BFOR signal basis is orthonormal, the L2 norm that quantifies the differences in the q-space signals of any two mDWI datasets can be easily computed as the sum of the squared differences in the BFOR expansion coefficients. In this work, we show that the reorientation of the $q$-space signal due to spatial transformation can be easily defined on the BFOR signal basis. We incorporate the BFOR signal basis into the LDDMM framework and derive the gradient descent algorithm for LDDMM-HYDI with explicit orientation optimization. Additionally, we extend the previous Bayesian atlas estimation framework for scalar-valued images to HYDIs and derive the expectation-maximization algorithm for solving the HYDI atlas estimation problem. Using real HYDI datasets, we show the Bayesian model generates the white matter atlas with anatomical details. Moreover, we show that it is important to consider the variation of mDWI reorientation due to a small change in diffeomorphic transformation in the LDDMM-HYDI optimization and to incorporate the full information of HYDI for aligning mDWI

Estimation of vector fields in unconstrained and inequality constrained variational problems for segmentation and registration

Vector fields arise in many problems of computer vision, particularly in non-rigid registration. In this paper, we develop coupled partial differential equations (PDEs) to estimate vector fields that define the deformation between objects, and the contour or surface that defines the segmentation of the objects as well.We also explore the utility of inequality constraints applied to variational problems in vision such as estimation of deformation fields in non-rigid registration and tracking. To solve inequality constrained vector field estimation problems, we apply tools from the Kuhn-Tucker theorem in optimization theory. Our technique differs from recently popular joint segmentation and registration algorithms, particularly in its coupled set of PDEs derived from the same set of energy terms for registration and segmentation. We present both the theory and results that demonstrate our approach