Feasibility of automated 3-dimensional magnetic resonance imaging pancreas segmentation.

PurposeWith the advent of MR guided radiotherapy, internal organ motion can be imaged simultaneously during treatment. In this study, we evaluate the feasibility of pancreas MRI segmentation using state-of-the-art segmentation methods.Methods and materialT2 weighted HASTE and T1 weighted VIBE images were acquired on 3 patients and 2 healthy volunteers for a total of 12 imaging volumes. A novel dictionary learning (DL) method was used to segment the pancreas and compared to t mean-shift merging (MSM), distance regularized level set (DRLS), graph cuts (GC) and the segmentation results were compared to manual contours using Dice's index (DI), Hausdorff distance and shift of the-center-of-the-organ (SHIFT).ResultsAll VIBE images were successfully segmented by at least one of the auto-segmentation method with DI >0.83 and SHIFT ≤2 mm using the best automated segmentation method. The automated segmentation error of HASTE images was significantly greater. DL is statistically superior to the other methods in Dice's overlapping index. For the Hausdorff distance and SHIFT measurement, DRLS and DL performed slightly superior to the GC method, and substantially superior to MSM. DL required least human supervision and was faster to compute.ConclusionOur study demonstrated potential feasibility of automated segmentation of the pancreas on MRI images with minimal human supervision at the beginning of imaging acquisition. The achieved accuracy is promising for organ localization

Self-correction of 3D reconstruction from multi-view stereo images

We present a self-correction approach to improving the 3D reconstruction of a multi-view 3D photogrammetry system. The self-correction approach has been able to repair the reconstructed 3D surface damaged by depth discontinuities. Due to self-occlusion, multi-view range images have to be acquired and integrated into a watertight nonredundant mesh model in order to cover the extended surface of an imaged object. The integrated surface often suffers from “dent” artifacts produced by depth discontinuities in the multi-view range images. In this paper we propose a novel approach to correcting the 3D integrated surface such that the dent artifacts can be repaired automatically. We show examples of 3D reconstruction to demonstrate the improvement that can be achieved by the self-correction approach. This self-correction approach can be extended to integrate range images obtained from alternative range capture devices

3D Object Reconstruction from Hand-Object Interactions

Recent advances have enabled 3d object reconstruction approaches using a single off-the-shelf RGB-D camera. Although these approaches are successful for a wide range of object classes, they rely on stable and distinctive geometric or texture features. Many objects like mechanical parts, toys, household or decorative articles, however, are textureless and characterized by minimalistic shapes that are simple and symmetric. Existing in-hand scanning systems and 3d reconstruction techniques fail for such symmetric objects in the absence of highly distinctive features. In this work, we show that extracting 3d hand motion for in-hand scanning effectively facilitates the reconstruction of even featureless and highly symmetric objects and we present an approach that fuses the rich additional information of hands into a 3d reconstruction pipeline, significantly contributing to the state-of-the-art of in-hand scanning.Comment: International Conference on Computer Vision (ICCV) 2015, http://files.is.tue.mpg.de/dtzionas/In-Hand-Scannin

Three-dimensional quantification and visualization of vascular networks in engineered tissues

Three-dimensional textural and volumetric image analysis holds great potential in understanding the image data produced by multi-photon microscopy. In this thesis, a tool that provides quantitative textural and morphometric analyzes of vasculature in engineered tissues, alongside with a fast three-dimensional volume rendering is proposed. The investigated 3D artificial tissues consist of Human Umbilical Vein Endothelial Cells (HUVEC) embedded in collagen exposed to two regimes of ultrasound standing wave fields under different pressure conditions. Textural features were evaluated over the extracted connected region in our samples using the normalized Gray Level Co-occurrence Matrix (GLCM) combined with Gray-Level Run Length Matrix (GLRLM) analysis. To minimize the error resulting from any possible volumetric rotation and to provide a comprehensive textural analysis, an averaged version of nine GLCM and GLRLM orientations is used. To evaluate volumetric features, parameters such as volume run length and percentage volume were utilized. The z-projection versions of the samples were used to estimate the tortuosity of the vessels, as well as, to measure the length and the angle of the branches. We utilized a three-dimensional volume rendering technique named MATVTK (derived from MATLAB and VTK) and runs under MATLAB that shows a great improvement on the processing time to reconstruct our volumes compared to MATLAB built-in functions. Results show that our analysis is able to differentiate among the exposed samples, due to morphological changes induced by the ultrasound standing wave fields. Furthermore, we demonstrate that providing more textural parameters than what is currently being reported in the literature, enhances the quantitative understanding of the heterogeneity of artificial tissues

Multi-touch 3D Exploratory Analysis of Ocean Flow Models

Modern ocean flow simulations are generating increasingly complex, multi-layer 3D ocean flow models. However, most researchers are still using traditional 2D visualizations to visualize these models one slice at a time. Properly designed 3D visualization tools can be highly effective for revealing the complex, dynamic flow patterns and structures present in these models. However, the transition from visualizing ocean flow patterns in 2D to 3D presents many challenges, including occlusion and depth ambiguity. Further complications arise from the interaction methods required to navigate, explore, and interact with these 3D datasets. We present a system that employs a combination of stereoscopic rendering, to best reveal and illustrate 3D structures and patterns, and multi-touch interaction, to allow for natural and efficient navigation and manipulation within the 3D environment. Exploratory visual analysis is facilitated through the use of a highly-interactive toolset which leverages a smart particle system. Multi-touch gestures allow users to quickly position dye emitting tools within the 3D model. Finally, we illustrate the potential applications of our system through examples of real world significance