Portinari: A Data Exploration Tool to Personalize Cervical Cancer Screening

Socio-technical systems play an important role in public health screening programs to prevent cancer. Cervical cancer incidence has significantly decreased in countries that developed systems for organized screening engaging medical practitioners, laboratories and patients. The system automatically identifies individuals at risk of developing the disease and invites them for a screening exam or a follow-up exam conducted by medical professionals. A triage algorithm in the system aims to reduce unnecessary screening exams for individuals at low-risk while detecting and treating individuals at high-risk. Despite the general success of screening, the triage algorithm is a one-size-fits all approach that is not personalized to a patient. This can easily be observed in historical data from screening exams. Often patients rely on personal factors to determine that they are either at high risk or not at risk at all and take action at their own discretion. Can exploring patient trajectories help hypothesize personal factors leading to their decisions? We present Portinari, a data exploration tool to query and visualize future trajectories of patients who have undergone a specific sequence of screening exams. The web-based tool contains (a) a visual query interface (b) a backend graph database of events in patients' lives (c) trajectory visualization using sankey diagrams. We use Portinari to explore diverse trajectories of patients following the Norwegian triage algorithm. The trajectories demonstrated variable degrees of adherence to the triage algorithm and allowed epidemiologists to hypothesize about the possible causes.Comment: Conference paper published at ICSE 2017 Buenos Aires, at the Software Engineering in Society Track. 10 pages, 5 figure

TEMPOS: A Platform for Developing Temporal Applications on Top of Object DBMS

This paper presents TEMPOS: a set of models and languages supporting the manipulation of temporal data on top of object DBMS. The proposed models exploit object-oriented technology to meet some important, yet traditionally neglected design criteria related to legacy code migration and representation independence. Two complementary ways for accessing temporal data are offered: a query language and a visual browser. The query language, namely TempOQL, is an extension of OQL supporting the manipulation of histories regardless of their representations, through fully composable functional operators. The visual browser offers operators that facilitate several time-related interactive navigation tasks, such as studying a snapshot of a collection of objects at a given instant, or detecting and examining changes within temporal attributes and relationships. TEMPOS models and languages have been formalized both at the syntactical and the semantical level and have been implemented on top of an object DBMS. The suitability of the proposals with regard to applications' requirements has been validated through concrete case studies

State-of-the-art on evolution and reactivity

This report starts by, in Chapter 1, outlining aspects of querying and updating resources on the Web and on the Semantic Web, including the development of query and update languages to be carried out within the Rewerse project. From this outline, it becomes clear that several existing research areas and topics are of interest for this work in Rewerse. In the remainder of this report we further present state of the art surveys in a selection of such areas and topics. More precisely: in Chapter 2 we give an overview of logics for reasoning about state change and updates; Chapter 3 is devoted to briefly describing existing update languages for the Web, and also for updating logic programs; in Chapter 4 event-condition-action rules, both in the context of active database systems and in the context of semistructured data, are surveyed; in Chapter 5 we give an overview of some relevant rule-based agents frameworks

The construction and interrogation of actor based simulation histories

Large socio-technical systems are complex to comprehend in their entirety because information exchanges between system compo- nents lend an emergent nature to the overall system behaviour. Although Individual system component behaviour may be known at the outset, such components may exhibit uncertainty and further exacerbate issues of a priori prediction of the overall system behaviour. Multi-agent sys- tems and the use of simulation is a possible recourse in such situations however, simulation results need to be correctly interpreted so as to nudge the overall system behaviour towards a desired objective. We pro- pose a solution wherein the system is modelled as a set of actors ex- changing messages, a simulation engine producing execution trace for an actor as its history, and a querying mechanism to identify patterns that may span across individual actor histories to ascertain property of the overall system. The proposed solution is evaluated using a representative sample from real life

The representation and management of evolving features in geospatial databases

Geographic features change over time, this change being the result of some kind of event or occurrence. It has been a research challenge to represent this data in a manner that reflects human perception. Most database systems used in geographic information systems (GIS) are relational, and change is either captured by exhaustively storing all versions of data, or updates replace previous versions. This stems from the inherent diffculty of modelling geographic objects in relational tables. This diffculty is compounded when the necessary time dimension is introduced to model how those objects evolve. There is little doubt that the object-oriented (OO) paradigm holds signi cant advantages over the relational model when it comes to modelling real-world entities and spatial data, and it is argued that this contention is particularly true when it comes to spatio-temporal data. This thesis describes an object-oriented approach to the design of a conceptual model for representing spatio-temporal geographic data, called the Feature Evolution Model (FEM), based on states and events. The model was used to implement a spatio-temporal database management system in Oracle Spatial, and an interface prototype is described that was used to evaluate the system by enabling querying and visualisation

State-of-the-art on evolution and reactivity

This report starts by, in Chapter 1, outlining aspects of querying and updating resources on the Web and on the Semantic Web, including the development of query and update languages to be carried out within the Rewerse project. From this outline, it becomes clear that several existing research areas and topics are of interest for this work in Rewerse. In the remainder of this report we further present state of the art surveys in a selection of such areas and topics. More precisely: in Chapter 2 we give an overview of logics for reasoning about state change and updates; Chapter 3 is devoted to briefly describing existing update languages for the Web, and also for updating logic programs; in Chapter 4 event-condition-action rules, both in the context of active database systems and in the context of semistructured data, are surveyed; in Chapter 5 we give an overview of some relevant rule-based agents frameworks