Communication and energy delivery architectures for personal medical devices

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p. 219-232).Advances in sensor technologies and integrated electronics are revolutionizing how humans access and receive healthcare. However, many envisioned wearable or implantable systems are not deployable in practice due to high energy consumption and anatomically-limited size constraints, necessitating large form-factors for external devices, or eventual surgical re-implantation procedures for in-vivo applications. Since communication and energy-management sub-systems often dominate the power budgets of personal biomedical devices, this thesis explores alternative usecases, system architectures, and circuit solutions to reduce their energy burden. For wearable applications, a system-on-chip is designed that both communicates and delivers power over an eTextiles network. The transmitter and receiver front-ends are at least an order of magnitude more efficient than conventional body-area networks. For implantable applications, two separate systems are proposed that avoid reimplantation requirements. The first system extracts energy from the endocochlear potential, an electrochemical gradient found naturally within the inner-ear of mammals, in order to power a wireless sensor. Since extractable energy levels are limited, novel sensing, communication, and energy management solutions are proposed that leverage duty-cycling to achieve enabling power consumptions that are at least an order of magnitude lower than previous work. Clinical measurements show the first system demonstrated to sustain itself with a mammalian-generated electrochemical potential operating as the only source of energy into the system. The second system leverages the essentially unlimited number of re-charge cycles offered by ultracapacitors. To ease patient usability, a rapid wireless capacitor charging architecture is proposed that employs a multi-tapped secondary inductive coil to provide charging times that are significantly faster than conventional approaches.by Patrick Philip Mercier.Ph.D

Verification and Performance Analysis of Time Base Coded Data Protocol

The recent improvements in implantable medical devices combined with advanced wireless sensor networks are set to revolutionize the health-care industry by providing real-time, low-cost health monitoring for the patients. A new-field called Implantable Wireless Body Sensor Networks (IWBSN) has become a hot research topic because of its energy constraints and complex design. The main components of IWBSN are the base-station and implantable sensor nodes. The most important challenge is designing the sensor nodes which has to stay inside the body for long time. A novel protocol called ``Time-Based Coded Data" (TBCD) was formed in an attempt to reduce the energy consumption in the sensor nodes. While validating TBCD protocol clock drift and wireless body channel were not considered. Clock drift causes the sensor nodes to go out of synchronisation in an inconsiderable period of time. The human tissues provides a high path loss to the wireless channel. This thesis proposes an error compensation method for both delay and clock drift. This helps the base-station and sensor nodes to stay synchronised for a longer period of time. The thesis also proposes a verification framework work which focusses on providing realistic situations to validate ultra low power IWBSNs. This framework enables to prove the functionality of TBCD protocol with delay and drift calculation and enables to find the optimum transmit power, sensitivity of the transceiver for TBCD protocol to work efficiently for an optimal distance between sensor nodes and the base-station. In addition, it has been proved that the life time of the battery of sensor nodes using TBCD protocol is greater when compared to the state-of-art protocols

Architecture for ultra-low power multi-channel transmitters for Body Area Networks using RF resonators

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2011.Cataloged from PDF version of thesis.Includes bibliographical references (p. 99-103).Body Area Networks (BANs) are gaining prominence for their use in medical and sports monitoring. This thesis develops the specifications of a ultra-low power 2.4GHz transmitter for use in a Body Area Networks, taking advantage of the asymmetric energy constraints on the sensor node and the basestation. The specifications include low transmit output powers, around -10dBm, low startup time, simple modulation schemes of OOK, FSK and BPSK and high datarates of 1Mbps. An architecture that is suited for the unique requirements of transmitters in these BANs is developed. RF Resonators, and in particular Film Bulk Acoustic Wave Resonators (FBARs) are explored as carrier frequency generators since they provide stable frequencies without the need for PLLs. The frequency of oscillation is directly modulated to generate FSK. Since these oscillators have low tuning range, the architecture uses multiple resonators to define the center frequencies of the multiple channels. A scalable scheme that uses a resonant buffer is developed to multiplex the oscillators' outputs to the Power Amplifier (PA). The buffer is also capable of generating BPSK signals. Finally a PA optimized for efficiently delivering the low output powers required in BANs is developed. A tunable matching network in the PA also enables pulse-shaping for spectrally efficient modulation. A prototype transmitter supporting 3 FBAR-oscillator channels in the 2.4GHz ISM band was designed in a 65nm CMOS process. It operates from a 0.7V supply for the RF portion and 1V for the digital section. The transmitter achieves 1Mbps FSK, up to 10Mbps for OOK and BPSK without pulse shaping and 1Mbps for OOK and BPSK with pulse shaping. The power amplifier has an efficiency of up to 43% and outputs between -15dBm and -7.5dBm onto a 50Q antenna. Overall, the transmitter achieves an efficiency of upto 26% and energy per bit of 483pJ/bit at 1Mbps.by Arun Paidimarri.S.M

A low power, reconfigurable fabric body area network for healthcare applications

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p. 105-110).Body Area Networks (BANs) are gaining prominence for their capability to revolutionize medical monitoring, diagnosis and treatment. This thesis describes a BAN that uses conductive fabrics (e-textiles) worn by the user to act as a power distribution and data communication network to sensors on the user's body. The network is controlled by a central hub in the form of a Base Station, which can either be a standalone device or can be embedded inside one of the user's portable electronic devices like a cellphone. Specifications for a Physical (PHY) layer and a Medium Access Control (MAC) layer have been developed that make use of the asymmetric energy budgets between the base station and sensor nodes in the network. The PHY layer has been designed to be suitable for the unique needs of such a BAN, namely easy reconfigurability, fault-tolerance and efficient energy and data transfer at low power levels. This is achieved by a mechanism for dividing the network into groups of sensors. The co-designed MAC layer is capable of supporting a wide variety of sensors with different data rate and network access requirements, ranging from EEG monitors to temperature sensors. Circuits have been designed at both ends of the network to transmit, receive and store power and data in appropriate frequency bands. Digital circuits have been designed to implement the MAC protocols. The base station and sensor nodes have been implemented in standard 180nm 1P6M CMOS process, and occupy an area 4.8mm2 and 3.6mm2 respectively. The base station has a minimum power consumption of 2.86mW, which includes the power transmitter, modulation and demodulation circuitry. The sensor nodes can recover up to 33.6paW power to supply to the biomedical signal acquisition circuitry with peak transfer efficiency of 1.2%.by Nachiket Venkappayya Desai.S.M

Ultra-Low-Power Sensors and Receivers for IoT Applications

The combination of ultra-low power analog front-ends and CMOS-compatible transducers enable new applications, such as environmental monitors, household appliances, health trackers, etc. that are seamlessly integrated into our daily lives. Furthermore, wireless connectivity allows many of these sensors to operate both independently and collectively. These techniques collectively fulfil the recent surge of internet-of-things (IoT) applications that have the potential to fundamentally change daily life for millions of people.In this dissertation, the circuit and system design of wireless receivers and sensors is presented that explores the challenges of implementing long lifespan, high accuracy, and large coverage range IoT sensor networks. The first is a wake-up receiver (WuRX), which continuously monitors the RF environment to wake up a higher-power radio upon detection of a predetermined RF signature. This work both improves sensitivity and reduces power over prior art through a multi-faceted design featuring an impedance transformation network with large passive voltage gain, an active envelope detector with high input impedance to facilitate large passive voltage gain, a low-power precision comparator, and a low-leakage digital baseband correlator.Although pushing the prior WuRX performance boundary by orders of magnitude, the first work shows moderate sensitivity, inferior temperature robustness, and large area with external lumped components. Thus, the second work shows a miniaturized WuRX that is temperature-compensated, yet still consumes only nano-watt power and millimeter area while operating at 9 GHz. To further reduce the area, a global common-mode feedback is utilized across the envelope detector and baseband amplifier that eliminates the need for off-chip ac-coupling components. Multiple temperature-compensation techniques are proposed to maintain constant bandwidth of the signal path and constant clock frequency. Both WuRXs operate at 0.4 V supply, consume near-zero power and achieve ~-70 dBm sensitivity.Lastly, the first reported CMOS 2-in-1 relative humidity and temperature sensor is presented. A unified analog front-end interfaces on-chip transducers and converts the inputs into a frequency vis a high-linearity frequency-locked loop. An incomplete-settling switched-capacitor-based Wheatstone bridge is proposed to sense the inputs in a power-efficient fashion

Energy aware network coding in wireless networks

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2012.Cataloged from PDF version of thesis.Includes bibliographical references (p. 97-104).Energy is one of the most important considerations in designing reliable low-power wireless communication networks. We focus on the problem of energy aware network coding. In particular, we investigate practical energy efficient network code design for wireless body area networks (WBAN). We first consider converge-cast in a star-shaped topology, in which a central base station (BS), or hub, manages and communicates directly with a set of nodes. We then consider a wireless-relay channel, in which a relay node assists in the transmission of data from a source to a destination. This wireless relay channel can be seen as a simplified extended star network, where nodes have relay capabilities. The objective is to investigate the use of network coding in these scenarios, with the goal of achieving reliability under low-energy and lower-power constraints. More specifically, in a star network, we propose a simple network layer protocol, study the mean energy to complete uploads of given packets from the nodes to the BS using a Markov chain model, and show through numerical examples that when reception energy is taken into account, the incorporation of network coding offers reductions in energy use. The amount of achievable gains depends on the number of nodes in the network, the degree of asymmetry in channel conditions experienced by different nodes, and the relative difference between transmitting and receiving power at the nodes. We also demonstrate the compatibility of the proposed scheme with the IEEE 802.15.6 WBAN standard by describing ways of incorporating network coding into systems compliant to the standard. For a wireless relay channel, we explore the strategic use of network coding according to both throughput and energy metrics. In the relay channel, a single source communicates to a single sink through the aid of a half-duplex relay. The fluid flow model is used to describe the case where both the source and the relay are coding, and Markov chain models are proposed to describe packet evolution if only the source or only the relay is coding. Although we do not attempt to explicitly categorize the optimal network coding strategies in the relay channel under different system parameters, we provide a framework for deciding whether and where to code, taking into account of throughput maximization and energy depletion constraints.by Xiaomeng Shi.Ph.D

Ultra-low-power circuits and systems for wearable and implantable medical devices

Thesis (Ph. D.)--Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (pages 219-231).Advances in circuits, sensors, and energy storage elements have opened up many new possibilities in the health industry. In the area of wearable devices, the miniaturization of electronics has spurred the rapid development of wearable vital signs, activity, and fitness monitors. Maximizing the time between battery recharge places stringent requirements on power consumption by the device. For implantable devices, the situation is exacerbated by the fact that energy storage capacity is limited by volume constraints, and frequent battery replacement via surgery is undesirable. In this case, the design of energy-efficient circuits and systems becomes even more crucial. This thesis explores the design of energy-efficient circuits and systems for two medical applications. The first half of the thesis focuses on the design and implementation of an ultra-low-power, mixed-signal front-end for a wearable ECG monitor in a 0.18pm CMOS process. A mixed-signal architecture together with analog circuit optimizations enable ultra-low-voltage operation at 0.6V which provides power savings through voltage scaling, and ensures compatibility with state-of-the-art DSPs. The fully-integrated front-end consumes just 2.9[mu]W, which is two orders of magnitude lower than commercially available parts. The second half of this thesis focuses on ultra-low-power system design and energy-efficient neural stimulation for a proof-of-concept fully-implantable cochlear implant. First, implantable acoustic sensing is demonstrated by sensing the motion of a human cadaveric middle ear with a piezoelectric sensor. Second, alternate energy-efficient electrical stimulation waveforms are investigated to reduce neural stimulation power when compared to the conventional rectangular waveform. The energy-optimal waveform is analyzed using a computational nerve fiber model, and validated with in-vivo ECAP recordings in the auditory nerve of two cats and with psychophysical tests in two human cochlear implant users. Preliminary human subject testing shows that charge and energy savings of 20-30% and 15-35% respectively are possible with alternative waveforms. A system-on-chip comprising the sensor interface, reconfigurable sound processor, and arbitrary-waveform neural stimulator is implemented in a 0.18[mu]m high-voltage CMOS process to demonstrate the feasibility of this system. The sensor interface and sound processor consume just 12[mu]W of power, representing just 2% of the overall system power which is dominated by stimulation. As a result, the energy savings from using alternative stimulation waveforms transfer directly to the system.by Marcus Yip.Ph.D

A 110μW [110 mu W] 10Mb/s eTextiles transceiver for body area networks with remote battery power

A transceiver for communicating over an electronic textiles medium is implemented for body area networks. A supply-rail-coupled differential signaling scheme permits time-sharing of the eTextiles medium between communication and remote powering circuits. Fabricated in 0.18 μm [mu m] CMOS and operating at 0.9 V, the chip consumes 110 μW [mu W] at a data rate of 10 Mb/s over a 1 m fabric link.Semiconductor Research Corporation. Center for Circuits and Systems Solutions (Contract 2003-CT-888